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Hotels in Eastern South Dakota

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Choose from 894 Eastern South Dakota Hotel Deals

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

3 out of 5
1301 West Russell Sioux Falls SD
  • 10 min walk from Denny Sanford Premier Center
Book a stay at this family-friendly hotel in Sioux Falls. Enjoy free WiFi, free parking, and 3 indoor pools. Our guests praise the pool and the helpful staff ...
7.6/10 Good! (1,464 reviews)
Pool was packed so didnt even go. Pool area and hallways smelled of pot. Supper was too expensive and waitress kept forgetting things. Hallways were loud from people shouting in their rooms. Pretty sure we will stay somewhere else next time its a couples stay.

Reviewed on Dec 26, 2025

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr
Comfort Inn & Suites at Sanford Sports Complex

Comfort Inn & Suites at Sanford Sports Complex

2.5 out of 5
3900 N HERCULES AVE Sioux Falls SD
  • 5 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (902 reviews)
Perfect stay. This is what clean, quiet and convenient looks like at an affordable price.

Reviewed on Dec 21, 2025

Comfort Inn & Suites at Sanford Sports Complex
AeroStay Hotel

AeroStay Hotel

2.5 out of 5
2821 N Jaycee Lane Sioux Falls SD
  • 5 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (1,040 reviews)
Friendly staff. Easy & quick check-in. We even were allowed to check in a little early.

Reviewed on Dec 25, 2025

AeroStay Hotel
Days Inn by Wyndham Sioux Falls Empire

Days Inn by Wyndham Sioux Falls Empire

2 out of 5
3401 Gateway Blvd Sioux Falls SD
  • 9 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,067 reviews)
Front desk staff made check in/out easy. Staff are friendly and courteous. The room was comfortable and clean.

Reviewed on Dec 27, 2025

Days Inn by Wyndham Sioux Falls Empire
Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3 out of 5
2320 South Louise Avenue Sioux Falls SD
  • 7 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
9.4/10 Exceptional! (1,000 reviews)
Good stay, clean room , quiet, good service

Reviewed on Dec 14, 2025

Clubhouse Hotel Suites Sioux Falls
La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

3 out of 5
4521 W. 41st Street Sioux Falls SD
  • 9 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,549 reviews)
nice

Reviewed on Dec 23, 2025

La Quinta Inn & Suites by Wyndham Sioux Falls
Hotel On Phillips

Hotel On Phillips

2.5 out of 5
100 N Phillips Ave Sioux Falls SD
  • 5 min drive from Denny Sanford Premier Center
Stay at this hotel in Sioux Falls. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful staff in our reviews. ...
9.4/10 Exceptional! (1,306 reviews)
Clean and spacious room.

Reviewed on Dec 28, 2025

Hotel On Phillips
Baymont by Wyndham Sioux Falls

Baymont by Wyndham Sioux Falls

2.5 out of 5
3200 South Meadow Avenue Sioux Falls SD
  • 9 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
8/10 Very Good! (1,812 reviews)
Room is clean. I do wish they’d get rid of the carpet though.

Reviewed on Dec 28, 2025

Baymont by Wyndham Sioux Falls
The Center Inn

The Center Inn

2.5 out of 5
900 E 20th St Sioux Falls SD
  • 7 min drive from Denny Sanford Premier Center
Stay at this hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (703 reviews)
Room was perfect! Staff was very helpful and informitive!

Reviewed on Dec 22, 2025

The Center Inn
Holiday Inn Sioux Falls-City Centre by IHG

Holiday Inn Sioux Falls-City Centre by IHG

3 out of 5
100 W 8th St Sioux Falls SD
  • 4 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8.4/10 Very Good! (999 reviews)
This was a Great Hotel! Clean, Nice Hot Tube, Staff was Super Nice!

Reviewed on Dec 22, 2025

Holiday Inn Sioux Falls-City Centre by IHG
Canopy By Hilton Sioux Falls Downtown

Canopy By Hilton Sioux Falls Downtown

4 out of 5
120 E. 4th Place Sioux Falls SD
  • 4 min drive from Denny Sanford Premier Center
Stay at this hotel in Sioux Falls. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Denny Sanford Premier Center and Falls Park ...
9.2/10 Wonderful! (159 reviews)
A very nice room in a new modern area

Reviewed on Dec 19, 2025

Canopy By Hilton Sioux Falls Downtown
Hampton Inn Sioux Falls

Hampton Inn Sioux Falls

2.5 out of 5
2417 S Carolyn Ave Sioux Falls SD
  • 7 min drive from Denny Sanford Premier Center
Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,009 reviews)
The front desk staff was awesome. We had a birthday party for a special needs child and the staff was so he!!

Reviewed on Dec 22, 2025

Hampton Inn Sioux Falls
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Eastern South Dakota

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Frequently Asked Questions About Eastern South Dakota hotels

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How many hotels are there in Eastern South Dakota?

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