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Columbia Regional

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Columbia Regional Flights as Low as $385

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Tue, Oct 7 - Tue, Oct 21
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$385 Roundtrip, found 4 days ago
$385
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Oct 7 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 21, priced at $385 found 4 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$389 Roundtrip, just found
$389
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $389 just found
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$394 Roundtrip, just found
$394
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $394 just found
American Airlines
Sat, Oct 11 - Mon, Oct 13
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$405 Roundtrip, found 4 days ago
$405
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Mon, Oct 13, priced at $405 found 4 days ago
American Airlines
Thu, Oct 9 - Sat, Oct 18
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$413 Roundtrip, found 4 days ago
$413
Roundtrip
found 4 days ago
Select American Airlines flight, departing Thu, Oct 9 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Sat, Oct 18, priced at $413 found 4 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$419 Roundtrip, just found
$419
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $419 just found
American Airlines
Tue, Oct 7 - Sat, Oct 11
SAV
Savannah - Hilton Head Intl.
COU
Columbia Regional
$419 Roundtrip, found 15 hours ago
$419
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Oct 7 from Savannah - Hilton Head Intl. to Columbia Regional, returning Sat, Oct 11, priced at $419 found 15 hours ago
American Airlines
Tue, Oct 7 - Sat, Oct 11
SAV
Savannah - Hilton Head Intl.
COU
Columbia Regional
$425 Roundtrip, found 15 hours ago
$425
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Oct 7 from Savannah - Hilton Head Intl. to Columbia Regional, returning Sat, Oct 11, priced at $425 found 15 hours ago
United
Sat, Oct 11 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$435 Roundtrip, found 5 days ago
$435
Roundtrip
found 5 days ago
Select United flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $435 found 5 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$436 Roundtrip, just found
$436
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $436 just found
United
Tue, Oct 7 - Mon, Oct 13
SAV
Savannah - Hilton Head Intl.
COU
Columbia Regional
$437 Roundtrip, found 5 days ago
$437
Roundtrip
found 5 days ago
Select United flight, departing Tue, Oct 7 from Savannah - Hilton Head Intl. to Columbia Regional, returning Mon, Oct 13, priced at $437 found 5 days ago
American Airlines
Sat, Oct 11 - Tue, Oct 14
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$441 Roundtrip, just found
$441
Roundtrip
just found
Select American Airlines flight, departing Sat, Oct 11 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 14, priced at $441 just found
United
Mon, Oct 6 - Fri, Oct 17
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$444 Roundtrip, found 5 days ago
$444
Roundtrip
found 5 days ago
Select United flight, departing Mon, Oct 6 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Fri, Oct 17, priced at $444 found 5 days ago
United
Sat, Oct 4 - Mon, Oct 13
SAV
Savannah - Hilton Head Intl.
COU
Columbia Regional
$446 Roundtrip, found 5 days ago
$446
Roundtrip
found 5 days ago
Select United flight, departing Sat, Oct 4 from Savannah - Hilton Head Intl. to Columbia Regional, returning Mon, Oct 13, priced at $446 found 5 days ago
American Airlines
Sat, Oct 4 - Tue, Oct 7
MSY
Louis Armstrong New Orleans Intl.
COU
Columbia Regional
$450 Roundtrip, found 7 hours ago
$450
Roundtrip
found 7 hours ago
Select American Airlines flight, departing Sat, Oct 4 from Louis Armstrong New Orleans Intl. to Columbia Regional, returning Tue, Oct 7, priced at $450 found 7 hours ago
United
Tue, Oct 7 - Fri, Oct 10
SAV
Savannah - Hilton Head Intl.
COU
Columbia Regional
$454 Roundtrip, found 5 days ago
$454
Roundtrip
found 5 days ago
Select United flight, departing Tue, Oct 7 from Savannah - Hilton Head Intl. to Columbia Regional, returning Fri, Oct 10, priced at $454 found 5 days ago

Cheap Flights to Columbia Regional

Fall in love at first flight with your vacation to Columbia Regional by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Columbia Regional on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Columbia Regional, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Columbia Regional

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Columbia Regional with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the COU airport.

What is the cheapest month to fly to Columbia Regional?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Columbia Regional are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Columbia Regional?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Columbia Regional.

What airport is best to fly into Columbia Regional?

When you’re planning your trip to Columbia Regional, convenience is the name of the game. Luckily, Columbia Regional Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Columbia Regional must-do list.

How much are flights to Columbia Regional?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Columbia Regional on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $385, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Columbia Regional?

The trick to saving a stack of cash on your flight to Columbia Regional? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $385 right now, why wait?

Columbia Regional Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Airlines serving
American Airlines, United
Number of airlines serving
2
Popular airline
American Airlines

Last Minute Hotel Deals in Columbia Regional

TownePlace Suites by Marriott Columbia

TownePlace Suites by Marriott Columbia

3 out of 5
4400 Nocona Parkway, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions A. Perry Philips Park and Philips ...
9/10 Wonderful! (344 reviews)
"There are no convenience or pharmacy stores nearby. Not even a grocery store"

Reviewed on Jul 31, 2025

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TownePlace Suites by Marriott Columbia
Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

3 out of 5
3301 LeMone Industrial Blvd, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Lazer Lanes and Walters-Boone ...
8.6/10 Excellent! (623 reviews)
"The room and bathroom were very clean, spacious, and comfortable!!"

Reviewed on Aug 4, 2025

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Courtyard by Marriott Columbia Missouri
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

2.5 out of 5
1402 Cinnamon Hill Lane, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
"Fast easy check in. Great breakfast bar."

Reviewed on Aug 7, 2025

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Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
Scenic Getaway w/ Fire Pit & Grill in Columbia!

Scenic Getaway w/ Fire Pit & Grill in Columbia!

3 out of 5
Columbia
Stay at this 3-star cottage in Columbia. Enjoy free parking, balconies, and an in-room coffeemaker. Popular attractions Cooper's Landing Marina and Plowboy Bend ...
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Scenic Getaway w/ Fire Pit & Grill in Columbia!
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd, Columbia, MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,288 reviews)
Great time
"The most comfortable beds you’ll ever sleep on, and a nice hot breakfast to go along with it. The hot tub was out of order during our stay but the pool was fantastic! Love the decorations and the people were friendly. It’s like the great wolf lodge but smaller :)"

Reviewed on Aug 6, 2025

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Stoney Creek Hotel Columbia
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,139 reviews)
"Staff was attentive and friendly, room clean and well appointed. GREAT value and I would definitely recommend."

Reviewed on Aug 11, 2025

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Wingate by Wyndham - Columbia
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,231 reviews)
Perfect!
"We arrived tired and hungry and were pleasantly surprised to find a complementary taco bar and drinks! The Hotel provided everything we needed!"

Reviewed on Aug 11, 2025

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Drury Plaza Hotel Columbia East
Relaxing Townhome, 4 Mi to Mizzou University!

Relaxing Townhome, 4 Mi to Mizzou University!

3.5 out of 5
Columbia
Stay at this 3.5-star business-friendly apartment in Columbia. Enjoy free parking and air conditioning. Popular attractions Cosmo-Bethel park and Bowden Park ...
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Relaxing Townhome, 4 Mi to Mizzou University!
See all 172 properties in Columbia Regional
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.