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Central Missouri

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Central Missouri Flights as Low as $318

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$318 Roundtrip, found 13 hours ago
$318
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $318 found 13 hours ago
United
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$318 Roundtrip, found 13 hours ago
$318
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $318 found 13 hours ago
United
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$324 Roundtrip, found 13 hours ago
$324
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $324 found 13 hours ago
United
Tue, May 12 - Tue, May 19
AUS
Austin-Bergstrom Intl.
COU
Columbia Regional
$336 Roundtrip, found 12 hours ago
$336
Roundtrip
found 12 hours ago
Select United flight, departing Tue, May 12 from Austin-Bergstrom Intl. to Columbia Regional, returning Tue, May 19, priced at $336 found 12 hours ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$341 Roundtrip, found 13 hours ago
$341
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $341 found 13 hours ago
United
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$356 Roundtrip, found 13 hours ago
$356
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $356 found 13 hours ago
United
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$361 Roundtrip, found 13 hours ago
$361
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $361 found 13 hours ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$368 Roundtrip, found 13 hours ago
$368
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $368 found 13 hours ago
United
Tue, May 12 - Tue, May 19
AUS
Austin-Bergstrom Intl.
COU
Columbia Regional
$372 Roundtrip, found 12 hours ago
$372
Roundtrip
found 12 hours ago
Select United flight, departing Tue, May 12 from Austin-Bergstrom Intl. to Columbia Regional, returning Tue, May 19, priced at $372 found 12 hours ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$384 Roundtrip, found 13 hours ago
$384
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $384 found 13 hours ago
United
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$389 Roundtrip, found 13 hours ago
$389
Roundtrip
found 13 hours ago
Select United flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $389 found 13 hours ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$391 Roundtrip, found 13 hours ago
$391
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $391 found 13 hours ago
United
Tue, May 12 - Tue, May 19
AUS
Austin-Bergstrom Intl.
COU
Columbia Regional
$397 Roundtrip, found 12 hours ago
$397
Roundtrip
found 12 hours ago
Select United flight, departing Tue, May 12 from Austin-Bergstrom Intl. to Columbia Regional, returning Tue, May 19, priced at $397 found 12 hours ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
DTW
Detroit Metropolitan Wayne County
COU
Columbia Regional
$398 Roundtrip, found 13 hours ago
$398
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Wed, Jun 3 from Detroit Metropolitan Wayne County to Columbia Regional, returning Sat, Jun 6, priced at $398 found 13 hours ago
United
Sat, May 9 - Fri, May 29
SNA
John Wayne
COU
Columbia Regional
$464 Roundtrip, found 1 day ago
$464
Roundtrip
found 1 day ago
Select United flight, departing Sat, May 9 from John Wayne to Columbia Regional, returning Fri, May 29, priced at $464 found 1 day ago
United
Fri, May 1 - Mon, May 4
CHS
Charleston Intl.
COU
Columbia Regional
$473 Roundtrip, found 13 hours ago
$473
Roundtrip
found 13 hours ago
Select United flight, departing Fri, May 1 from Charleston Intl. to Columbia Regional, returning Mon, May 4, priced at $473 found 13 hours ago

Cheap Flights to Central Missouri

Fall in love at first flight with your vacation to Central Missouri by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Central Missouri on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Central Missouri, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Central Missouri

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Central Missouri with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MKC airport.

What is the cheapest month to fly to Central Missouri?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Central Missouri are in June, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Central Missouri?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Central Missouri.

What airport is best to fly into Central Missouri?

When you’re planning your trip to Central Missouri, convenience is the name of the game. Luckily, Central Missouri Roy Otten Memorial Airfield Airport is nearby so you can deplane and get going on checking off everything on your Central Missouri must-do list.

How much are flights to Central Missouri?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Central Missouri on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $318, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Central Missouri?

The trick to saving a stack of cash on your flight to Central Missouri? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $318 right now, why wait?

Central Missouri Flight Information
Destination airport
Columbia Regional
Destination airport IATA code
COU
Roundtrip price
$328

Last Minute Hotel Deals in Central Missouri

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
Book a stay at this spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (1,007 reviews)
Older property but maintained.

Reviewed on Apr 25, 2026

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Margaritaville Lake Resort Lake of the Ozarks
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

2.5 out of 5
817 N Keene St Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,795 reviews)
Friendly staff and clean hotel

Reviewed on Apr 25, 2026

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Country Inn & Suites by Radisson, Columbia, MO
Capitol Plaza Hotel Jefferson City

Capitol Plaza Hotel Jefferson City

3.5 out of 5
Jefferson City 415 W. McCarty St Jefferson City MO
Book a stay at this business-friendly hotel in Jefferson City. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff ...
7/10 Good! (1,005 reviews)
Phhh. Hhft

Reviewed on Apr 26, 2026

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Capitol Plaza Hotel Jefferson City
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

3 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,429 reviews)
Really enjoyed my stay we’ll definitely stay again. I have stayed at several different properties. The food was great. The room was clean very quiet. The only issue I had was the young lady that was doing the alcoholic drinks in the evening. I asked her for a sangria, which was just juice with the ...

Reviewed on Apr 22, 2026

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Drury Plaza Hotel Columbia East
Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2.5 out of 5
2500 I 70 Dr Sw Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
8.4/10 Very Good! (763 reviews)
Nothing fancy but all perfectly pleasant.

Reviewed on Apr 23, 2026

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Baymont by Wyndham Columbia, MO
Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
Book a stay at this beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (1,111 reviews)
This was a great find. Staff was super friendly the only problem I had was the room and the balcony area had a lot of spider webs

Reviewed on Apr 21, 2026

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Lodge Of Four Seasons Golf Resort, Marina & Spa
Wyndham Executive Center Columbia

Wyndham Executive Center Columbia

3.5 out of 5
2200 I-70 Drive SW Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,001 reviews)
Very nice hotel but my room was not ready at check-in and I asked 3 times for someone to come make up my other bed and it was never taken care of

Reviewed on Apr 21, 2026

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Wyndham Executive Center Columbia
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

3 out of 5
3101 Wingate Ct Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,225 reviews)
A hidden gem!!! Great rooms. Safe location. Everyday, staff was working hard to keep the hotel maintained and clean. The pool and hot tub were balanced daily. Very impressed with my overall experience

Reviewed on Apr 26, 2026

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Wingate by Wyndham - Columbia
See all 4,972 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Hotels With Free Airport Shuttle

Courtyard by Marriott Columbia Missouri

Courtyard by Marriott Columbia Missouri

3 out of 5
3301 LeMone Industrial Blvd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Walters-Boone County Historic ...
8.6/10 Excellent! (687 reviews)
The advertised amenity of a 24/7 available airport shuttle is NOT honest. While staff was kind, no staff was available for trip from airport to hotel, and when I inquired about arranging a ride back, it came with a very narrow window of potential that left me feeling uncertain if I’d be able to use ...

Reviewed on Apr 6, 2026

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Courtyard by Marriott Columbia Missouri
Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

2.5 out of 5
2601 S Providence Rd Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,369 reviews)
The toilet was leaking. Other than that, it was a great stay.

Reviewed on Apr 26, 2026

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Stoney Creek Hotel Columbia
The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

4 out of 5
1111 E Broadway Columbia MO
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (1,000 reviews)
We returned to the hotel fully expecting to have a late dinner and they had inexplicably closed the kitchen early. Not only were we price gouged because it was mom’s weekend for many sororities (I paid half what I paid this trip, last month), but then to not be able to eat dinner was unacceptable. ...

Reviewed on Apr 21, 2026

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The Broadway Columbia - a DoubleTree by Hilton
See all 4,972 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.