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A modern building with colorful geometric shapes and a clear blue sky.

Ancon
Panama City
Panamá Province
Panama
Mexico and Central America
Hotwire.com

Ancon Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Casa Lefevre By Wynwood House

3.5 out of 5

Price was $989, price is now $718 per person

$718

per person

Oct 1 - Oct 5

found 10 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

If you want to explore Casco Viejo, the location does not get any better than this. The balcony faces Cathedral Plaza and is a quick walk to many galleries, restaurants and clubs. The apartment I was in had lots of charm and a great use of space. The check in and check out process was super easy. Also, the Wynwood team is always available on WhatsApp if there are any issues or if you need anything.

Reviewed on May 19, 2026

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $2,095, price is now $1,065 per person

$1,065

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Love the breakfast and the rooms were amazing

Reviewed on Jul 5, 2026

Megapolis Hotel Panamá

4.5 out of 5

Save 100% on your flight

Price was $1,676, price is now $1,005 per person

$1,005

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

The staff was very helpful the hotel was nice and clean. Wonderful hotel I would definitely recommend

Reviewed on Jul 6, 2026

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,414, price is now $915 per person

$915

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Very beautiful and convenient in every way possible.

Reviewed on Jul 6, 2026

Hotel Riu Plaza Panama

5 out of 5

Price was $1,389, price is now $967 per person

$967

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

The breakfast buffet is amazing,more variety that the cruise’s buffet

Reviewed on Jul 6, 2026

80m² Luxury Ocean View Apartment PH The Sands, Next to Hilton

2 out of 5

Save 100% on your flight

Price was $1,820, price is now $1,282 per person

$1,282

per person

Aug 10 - Aug 17

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy a fitness center, parking (surcharge), and an outdoor pool. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Decapolis Hotel Panama City

4 out of 5

Price was $1,298, price is now $932 per person

$932

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Ubicación, limpieza, y piscina con vista panaromica a la ciudad

Reviewed on Jul 6, 2026

Las Clementinas

3.5 out of 5

Price was $1,596, price is now $1,149 per person

$1,149

per person

Sep 13 - Sep 19

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

The door handle broke and we got locked in the room, then that night a high pitched alarm went off and I had to call multiple times for someone to turn it off. They did after an hour or more and then it came back on a few hours later. No offer of apology or compensation for lost sleep. The staff is wonderful. Friendly and did their best, but I would not recommend.

Reviewed on Jul 5, 2026