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Santo Domingo Vacation Packages

Build your package with 2 more options

Santo Domingo Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Price was $984, price is now $667 per person
$667
per person
Jan 22 - Jan 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Save 100% on your flight
Price was $1,951, price is now $1,067 per person
$1,067
per person
Feb 12 - Feb 17
found 7 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Save 100% on your flight
Price was $2,298, price is now $1,396 per person
$1,396
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,339, price is now $867 per person
$867
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this apartment in Las Cumbres. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions El Peñón and Summit Botanical Gardens & Zoo are located nearby.
La Cuadra by Wynwood House

La Cuadra by Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,305, price is now $849 per person
$849
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and cable TV channels. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Contemporanea by Wynwood House

Casa Contemporanea by Wynwood House

4 out of 5
Save 100% on your flight
Price was $1,697, price is now $1,118 per person
$1,118
per person
Feb 13 - Feb 20
found 15 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, satellite TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa La Costa By Wynwood House

Casa La Costa By Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,019, price is now $702 per person
$702
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo

3 out of 5
Price was $1,537, price is now $1,072 per person
$1,072
per person
Feb 12 - Feb 17
found 7 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Santo Domingo Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
The Westin Panama

The Westin Panama

4 out of 5
Costa del Este
Price was $858, price is now $643 per person
$643
per person
Feb 5 - Feb 8
found 24 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $1,996, price is now $1,431 per person
$1,431
per person
Jan 2 - Jan 6
found 15 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $3,326, price is now $2,413 per person
$2,413
per person
Jan 1 - Jan 4
found 10 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
Price was $1,100, price is now $822 per person
$822
per person
Jan 4 - Jan 8
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Panama City (PTY)

Santo Domingo Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
La Cuadra by Wynwood House

La Cuadra by Wynwood House

3.5 out of 5
El Chorrillo
Save 100% on your flight
Price was $1,305, price is now $849 per person
$849
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,951, price is now $1,067 per person
$1,067
per person
Feb 12 - Feb 17
found 7 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Casa Mallet by Wynwood House

Casa Mallet by Wynwood House

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $2,298, price is now $1,396 per person
$1,396
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House

3.5 out of 5
Save 100% on your flight
Price was $1,339, price is now $867 per person
$867
per person
Feb 4 - Feb 10
found 5 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sat, Jan 10 - Wed, Feb 11
PTY
Tocumen Intl.
DAV
Enrique Malek Intl.
$101 Roundtrip, found 4 hours ago
$101
Roundtrip
found 4 hours ago
Select Copa flight, departing Sat, Jan 10 from Tocumen Intl. to Enrique Malek Intl., returning Wed, Feb 11, priced at $101 found 4 hours ago
Copa
Mon, Dec 29 - Thu, Feb 5
PTY
Tocumen Intl.
DAV
Enrique Malek Intl.
$103 Roundtrip, found 3 days ago
$103
Roundtrip
found 3 days ago
Select Copa flight, departing Mon, Dec 29 from Tocumen Intl. to Enrique Malek Intl., returning Thu, Feb 5, priced at $103 found 3 days ago
Copa
Wed, Jan 7 - Thu, Feb 12
PTY
Tocumen Intl.
DAV
Enrique Malek Intl.
$116 Roundtrip, found 2 days ago
$116
Roundtrip
found 2 days ago
Select Copa flight, departing Wed, Jan 7 from Tocumen Intl. to Enrique Malek Intl., returning Thu, Feb 12, priced at $116 found 2 days ago
Copa
Wed, Dec 31 - Wed, Dec 31
SJO
Juan Santamaría Intl.
DAV
Enrique Malek Intl.
$239 Roundtrip, found 1 day ago
$239
Roundtrip
found 1 day ago
Select Copa flight, departing Wed, Dec 31 from Juan Santamaría Intl. to Enrique Malek Intl., returning Wed, Dec 31, priced at $239 found 1 day ago