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Holiday Inn Express & Suites Sanford- Lake Mary by IHG

Holiday Inn Express & Suites Sanford- Lake Mary by IHG

4 out of 5
4750 W State Road 46 Sanford FL
  • 4 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,175 reviews)
"It was close to my family in Sandford and everything was close by. Very clean and new and had also breakfast ."

Reviewed on Jul 5, 2026

Holiday Inn Express & Suites Sanford- Lake Mary by IHG
Best Western Plus Sanford Airport/Lake Mary Hotel

Best Western Plus Sanford Airport/Lake Mary Hotel

2.5 out of 5
3401 S Orlando Dr Sanford FL
  • 11 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.4/10 Good! (1,601 reviews)
"Bathrooms need an upgrade. Very dirty with loose fixtures."

Reviewed on Jun 30, 2026

Best Western Plus Sanford Airport/Lake Mary Hotel
Comfort Inn & Suites Orlando North

Comfort Inn & Suites Orlando North

2.5 out of 5
590 Ava Ct Sanford FL
  • 28 min walk from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,305 reviews)
"Me encanto todo muy amable y servicial y las habitaciones 100 recomendado Volveria"

Reviewed on Jul 2, 2026

Comfort Inn & Suites Orlando North
Comfort Inn & Suites Orlando Sanford Airport

Comfort Inn & Suites Orlando Sanford Airport

2.5 out of 5
3043 East Lake Mary Boulevard Sanford FL
  • 17 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Sanford. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Seminole County Sports Complex ...
9.8/10 Exceptional! (114 reviews)
"We had a wonderful stay! The hotel was very clean, comfortable, and well maintained. The staff was friendly, welcoming, and always willing to help. The location was perfect, and the amenities exceeded our expectations. We truly enjoyed our time here and would definitely stay again. Highly ..."

Reviewed on Jul 5, 2026

Comfort Inn & Suites Orlando Sanford Airport
La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport

3 out of 5
7160 N Frontage Rd Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the helpful staff and ...
7.4/10 Good! (2,268 reviews)
"Breakfast was subpar; the pool needed cleaning; the airport shuttle was terrible. Waited 2 hours at the airport until they were able to find a driver. The vehicle was dirty and smelley but the driver was pleasant. The hotel itself needs serious renovations. The lobbly was impressing but that was ..."

Reviewed on Jul 5, 2026

La Quinta Inn & Suites by Wyndham Orlando Airport
Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport

2.5 out of 5
5767 T.G. Lee Blvd. Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,022 reviews)
"La estadía fue tranquila, amable, limpia la habitación, amenities necesarias, un poco húmedo el ambiente en la habitación y baño, cama cómoda, buena relación calidad precio."

Reviewed on Jul 5, 2026

Hampton Inn Orlando-International Airport
Sheraton Orlando North Hotel

Sheraton Orlando North Hotel

3.5 out of 5
600 N Lake Destiny Dr Maitland FL
  • 34 min drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Maitland. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,226 reviews)
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Reviewed on Jul 5, 2026

Sheraton Orlando North Hotel
Country Inn & Suites by Radisson, Orlando Airport, FL

Country Inn & Suites by Radisson, Orlando Airport, FL

3 out of 5
5440 Forbes Pl Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8/10 Very Good! (4,678 reviews)
"It was great"

Reviewed on Jul 5, 2026

Country Inn & Suites by Radisson, Orlando Airport, FL
Spark by Hilton Orlando near Universal

Spark by Hilton Orlando near Universal

2.5 out of 5
5635 Windhover Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,366 reviews)
"Good!!"

Reviewed on Jul 5, 2026

Spark by Hilton Orlando near Universal
Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport

3 out of 5
7500 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.4/10 Very Good! (5,943 reviews)
"It is a new building and it has good hospitality"

Reviewed on Jul 5, 2026

Ramada by Wyndham Suites Orlando Airport
DoubleTree by Hilton Orlando Airport

DoubleTree by Hilton Orlando Airport

4 out of 5
5555 Hazeltine National Drive Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Stay at this hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (2,471 reviews)
"This location is truly lovely"

Reviewed on Jul 5, 2026

DoubleTree by Hilton Orlando Airport
Sheraton Suites Orlando Airport

Sheraton Suites Orlando Airport

3.5 out of 5
7550 Augusta National Dr Orlando FL
  • 1 hour drive from Central Florida Zoo & Botanical Gardens
Book a stay at this business-friendly hotel in Orlando. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
8.6/10 Excellent! (2,099 reviews)
"great service, good food, clean and bug rooms"

Reviewed on Jul 4, 2026

Sheraton Suites Orlando Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Sanford

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Choosing the right hotel in Florida has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Sanford’s 2,421 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $83. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Sanford hotel deals at the last minute.

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Frequently Asked Questions About Sanford hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Sanford?

With over 2,421 hotels in Sanford, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $83.

How to find cheap car rentals in Sanford?

Finding a cheap car rental deal in Sanford is as easy as scoring cheap hotels in Sanford. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.