Search for Cheap Deals on
Hotels in San Luis

Choose from 205 San Luis Hotel Deals

Howard Johnson by Wyndham Yuma
Howard Johnson by Wyndham Yuma
2 out of 5
3181 S 4th Ave, Yuma, AZ
  • 32 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,009 reviews)
"Nothing special about the property,but was clean.The toilets need to changed to handicap toilets"

Reviewed on May 23, 2025

Howard Johnson by Wyndham Yuma
La Fuente Inn & Suites
La Fuente Inn & Suites
3 out of 5
1513 E 16th St, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9.2/10 Wonderful! (1,929 reviews)
"The place was clean and comfortable. The pool was really great. We would stay again if we were in the area"

Reviewed on May 27, 2025

La Fuente Inn & Suites
Shilo Inn Hotel & Suites - Yuma
Shilo Inn Hotel & Suites - Yuma
2.5 out of 5
1550 S Castle Dome Ave, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (1,002 reviews)
"Nice and clean nice lobby and room and bed comfortable."

Reviewed on May 17, 2025

Shilo Inn Hotel & Suites - Yuma
Motel 6 Yuma, AZ - East
Motel 6 Yuma, AZ - East
2 out of 5
1445 E 16th St, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Stay at this motel in Yuma. Enjoy free parking, a 24-hour front desk, and a snack bar/deli. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.8/10 Good! (1,006 reviews)
Good for Overnight Stay
"Clean and comfortable older hotel. No frills for an overnight stay."

Reviewed on May 25, 2025

Motel 6 Yuma, AZ - East
Wingate by Wyndham Yuma
Wingate by Wyndham Yuma
2.5 out of 5
1760 Sunridge Dr, Yuma, AZ
  • 36 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9/10 Wonderful! (1,046 reviews)
"Great staff"

Reviewed on May 23, 2025

Wingate by Wyndham Yuma
Radisson Hotel Yuma
Radisson Hotel Yuma
3.5 out of 5
1501 S Redondo Center Drive, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Stay at this 3.5-star eco-certified hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,001 reviews)
"Very friendly and hospitable staff, restaurant is excellent!!"

Reviewed on May 21, 2025

Radisson Hotel Yuma
Ramada by Wyndham Yuma
Ramada by Wyndham Yuma
3 out of 5
711 E 32nd St, Yuma, AZ
  • 32 min drive from San Luis Lakes State Park
Stay at this motel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
7.6/10 Good! (1,013 reviews)
"Front desk grls very nice, pool clean & very refreshing, room was nice. I was there 3 nights they did not cime tho to clean, giv towelss etc i had to call 2x to get towels & i cleaned room myself Was overall good stay. The overwhelming smell of the Indian restraunt thts attached in lovby was very ..."

Reviewed on May 22, 2025

Ramada by Wyndham Yuma
Best Western Yuma Mall Hotel & Suites
Best Western Yuma Mall Hotel & Suites
3 out of 5
1450 S Castle Dome Ave, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,006 reviews)
"Clean rooms and well stocked. Plus lots of fast food spots around, and some decent restaurants too."

Reviewed on May 23, 2025

Best Western Yuma Mall Hotel & Suites
La Quinta Inn & Suites By Wyndham Yuma
La Quinta Inn & Suites By Wyndham Yuma
3 out of 5
770 S Castle Dome Ave, Yuma, AZ
  • 39 min drive from San Luis Lakes State Park
Stay at this 3-star hotel in Yuma. Enjoy free breakfast, free parking, and WiFi (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (320 reviews)
"I enjoyed the cleaness of the property. Also the small concessions stand it was very helpful when traveling with children. Room service ladies very nice and helpful."

Reviewed on May 26, 2025

La Quinta Inn & Suites By Wyndham Yuma
Quality Inn & Suites Yuma
Quality Inn & Suites Yuma
2.5 out of 5
1691 S Riley Ave, Yuma, AZ
  • 36 min drive from San Luis Lakes State Park
Stay at this hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,008 reviews)
"Nice and Clean"

Reviewed on May 25, 2025

Quality Inn & Suites Yuma
Days Inn by Wyndham Yuma
Days Inn by Wyndham Yuma
2 out of 5
1671 E 16th St, Yuma, AZ
  • 37 min drive from San Luis Lakes State Park
Book a stay at this business-friendly hotel in Yuma. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.8/10 Good! (1,001 reviews)
"Only nowhere was I informed about the $50 deposit, it wasn't annoying but I wasn't informed anywhere until it was time to check in."

Reviewed on May 22, 2025

Days Inn by Wyndham Yuma
Budgetel Inn & Suites Yuma
Budgetel Inn & Suites Yuma
2.5 out of 5
1640 S Arizona Avenue, Yuma, AZ
  • 36 min drive from San Luis Lakes State Park
Stay at this hotel in Yuma. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
6.6/10 (1,001 reviews)
"Nice staff Clean rooms 🙂"

Reviewed on May 26, 2025

Budgetel Inn & Suites Yuma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in San Luis

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your San Luis hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in San Luis.

Choosing the right hotel in Arizona has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of San Luis’s 205 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $63. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great San Luis hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in San Luis. No matter your reason for visiting San Luis, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About San Luis hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in San Luis for as low as $63.

How many hotels are there in San Luis?

With over 205 hotels in San Luis, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $63.

How to find cheap car rentals in San Luis?

Finding a cheap car rental deal in San Luis is as easy as scoring cheap hotels in San Luis. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.