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Mission District Vacation Packages

Mission District Flight + Hotel packages

Price found within the past 48 hours. Click for updated prices.
The Mosser

The Mosser

3 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Stay at this 3-star hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Oracle Park and Chase Center are located nearby.
San Francisco Proper Hotel

San Francisco Proper Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 3 hours ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Stay at this 4-star hotel in San Francisco. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Oracle Park and Lombard Street are located nearby.
Hotel Majestic

Hotel Majestic

3.5 out of 5
Western Addition
per person
Jun 2 - Jun 6
found 6 hours ago
Roundtrip non-stop flight included
Boston (BOS) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Lombard Street and Pier 39 are located nearby.
The Pickwick Hotel

The Pickwick Hotel

3.5 out of 5
Downtown San Francisco
per person
Jun 12 - Jun 16
found 10 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Francisco (SFO)
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Oracle Park and Chase Center are located nearby.
1 Hotel San Francisco

1 Hotel San Francisco

5 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 2 - Jun 6
found 6 hours ago
Roundtrip non-stop flight included
Boston (BOS) to San Francisco (SFO)
Stay at this 5-star luxury hotel in San Francisco. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Oracle Park and Pier 39 are located nearby.
Homewood Suites by Hilton San Francisco Airport North

Homewood Suites by Hilton San Francisco Airport North

3 out of 5
per person
Jun 24 - Jun 28
found 11 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Francisco (SFO)
Stay at this 3-star business-friendly hotel in Brisbane. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions San Francisco Bay and Cow Palace are located nearby.
Hampton Inn San Francisco Downtown/Convention Center

Hampton Inn San Francisco Downtown/Convention Center

3 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Stay at this 3-star hotel in San Francisco. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Oracle Park and Chase Center are located nearby.
HYATT house Belmont/Redwood Shores

HYATT house Belmont/Redwood Shores

3 out of 5
per person
Jun 24 - Jun 28
found 11 hours ago
Roundtrip non-stop flight included
Philadelphia (PHL) to San Francisco (SFO)
Book a stay at this business-friendly hotel in Belmont. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Lakeshore Park Beach and Hiller Aviation Museum are located nearby.

3-4 Night Vacations in Mission District

Price found within the past 48 hours. Click for updated prices.
Hotel EPIK

Hotel EPIK

2.5 out of 5
Downtown San Francisco
per person
Jun 16 - Jun 20
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
The Andrews Hotel

The Andrews Hotel

3 out of 5
Union Square
per person
Jun 16 - Jun 20
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
per person
Jun 16 - Jun 20
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Hampton Inn San Francisco Downtown/Convention Center

Hampton Inn San Francisco Downtown/Convention Center

3 out of 5
Downtown San Francisco
per person
Jun 16 - Jun 20
found 2 days ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)

5-7 Night Vacations in Mission District

Price found within the past 48 hours. Click for updated prices.
The Mosser

The Mosser

3 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
San Francisco Proper Hotel

San Francisco Proper Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 3 hours ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Hampton Inn San Francisco Downtown/Convention Center

Hampton Inn San Francisco Downtown/Convention Center

3 out of 5
Downtown San Francisco
Save 100% on your flight
per person
Jun 3 - Jun 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
per person
Jun 3 - Jun 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to San Francisco (SFO)

Cheap Hotel Deals in Mission District

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
Hotel Riu Plaza Fisherman's Wharf
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4 out of 5
450 Powell Street, San Francisco, CA
Stay at this 4-star historic hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
Beacon Grand, A Union Square Hotel
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Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 out of 5
433 Powell St, San Francisco, CA
Stay at this 3.5-star hotel in San Francisco. Enjoy free WiFi, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and the clean ...
Chancellor Hotel on Union Square
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St, San Francisco, CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, a fitness center, and valet parking (surcharge). Our guests praise the pool and ...
Handlery Union Square Hotel
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

4 out of 5
55 Cyril Magnin St, San Francisco, CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 restaurants, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
Parc 55 San Francisco - A Hilton Hotel
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St, San Francisco, CA
Stay at this 4-star business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Club Quarters Hotel in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, May 20 - Tue, May 27
LAX
Los Angeles Intl.
SFO
San Francisco Intl.
$94 Roundtrip, found 1 day ago
$94
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Tue, May 20 from Los Angeles Intl. to San Francisco Intl., returning Tue, May 27, priced at $94 found 1 day ago
Spirit Airlines
Tue, Jun 10 - Wed, Jun 11
LAX
Los Angeles Intl.
OAK
Oakland Intl.
$119 Roundtrip, found 2 days ago
$119
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Tue, Jun 10 from Los Angeles Intl. to Oakland Intl., returning Wed, Jun 11, priced at $119 found 2 days ago
Alaska Airlines
Fri, May 9 - Tue, May 13
ORD
O'Hare Intl.
SFO
San Francisco Intl.
$181 Roundtrip, found 2 days ago
$181
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Fri, May 9 from O'Hare Intl. to San Francisco Intl., returning Tue, May 13, priced at $181 found 2 days ago
Bargain Flight
Fri, May 9 - Tue, May 13
EWR
Newark Liberty Intl. Airport
SFO
San Francisco Intl.
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, May 9 from Newark Liberty Intl. Airport to San Francisco Intl., returning Tue, May 13, priced at $197 found 1 day ago