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Hotels in Melrose

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Choose from 797 Melrose Hotel Deals

hom hotel + suites, Trademark Collection by Wyndham

hom hotel + suites, Trademark Collection by Wyndham

2.5 out of 5
3905 Sw 43rd St, Gainesville, FL
  • 22 min drive from Santa Fe Lake
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.2/10 Very Good! (1,700 reviews)
"Friendly staff"

Reviewed on Jul 22, 2025

hom hotel + suites, Trademark Collection by Wyndham
Hyatt Place Gainesville Downtown

Hyatt Place Gainesville Downtown

3 out of 5
212 SE 1ST STREET,, Gainesville, FL
  • 17 min drive from Santa Fe Lake
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,021 reviews)
"Good area, nice rooms and clean. Worked out great."

Reviewed on Jul 28, 2025

Hyatt Place Gainesville Downtown
Hotel Eleo at the University of Florida

Hotel Eleo at the University of Florida

3 out of 5
1514 Southwest 14th Street, Gainesville, FL
  • 19 min drive from Santa Fe Lake
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free WiFi, free valet parking, and breakfast (surcharge). Our guests praise the restaurant ...
9.4/10 Exceptional! (1,272 reviews)
"the housekeeping did not replace any toiletries/amenities such as makeup remover or lotion on our second day"

Reviewed on Jul 29, 2025

Hotel Eleo at the University of Florida
Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL

3 out of 5
4015 Sw 43rd St, Gainesville, FL
  • 23 min drive from Santa Fe Lake
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,446 reviews)
"Every thing was great except the indoor pool was very cold"

Reviewed on Jul 29, 2025

Country Inn & Suites by Radisson, Gainesville, FL
Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG

3.5 out of 5
5020 SW 30th Lane, Gainesville, FL
  • 21 min drive from Santa Fe Lake
Stay at this 3.5-star business-friendly hotel in Gainesville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,012 reviews)
"Excellent location, property, and staff!"

Reviewed on Jul 28, 2025

Hotel Indigo Gainesville-Celebration Pointe by IHG
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

3 out of 5
4000 Southwest 40th Blvd, Gainesville, FL
  • 22 min drive from Santa Fe Lake
Stay at this 3-star business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,277 reviews)
"We need more DRURY Inns in the USA…they are the best hotels I’ve ever stayed in & I will choose them over all others. I can’t say one bad thing about the property"

Reviewed on Jul 28, 2025

Drury Inn & Suites Gainesville
Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

2.5 out of 5
3500 Southwest 42nd St, Gainesville, FL
  • 22 min drive from Santa Fe Lake
Stay at this hotel in Gainesville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,159 reviews)
Road trip
"Older hotel, but has been updated. Clean. We had double beds, smaller than we like. One bed was OK, but not overly comfortable- the other bed broken down and one could feel the springs. Breakfast was the usual hotel breakfast with sausage, powdered eggs, yogurt, etc. Pet friendly!"

Reviewed on Jul 26, 2025

Red Roof Inn PLUS+ Gainesville
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2.5 out of 5
2603 SW 13TH STREET, Gainesville, FL
  • 20 min drive from Santa Fe Lake
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,025 reviews)
"Nice clean and welcoming hotel chain. This one stood out for its super front desk clerk on duty Edgar. Super host! The check in was a breeze!"

Reviewed on Jul 24, 2025

Comfort Suites Gainesville near University
Quality Inn Gainesville near University

Quality Inn Gainesville near University

2.5 out of 5
2435 Sw 13th Street, Gainesville, FL
  • 20 min drive from Santa Fe Lake
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,000 reviews)
"Good for 2 nights stay"

Reviewed on Jul 24, 2025

Quality Inn Gainesville near University
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

4 out of 5
3726 Sw 40th Blvd, Gainesville, FL
  • 22 min drive from Santa Fe Lake
Stay at this 4-star hotel in Gainesville. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in ...
7.6/10 Good! (1,010 reviews)
"Not my favorite hilton, but a great location."

Reviewed on Jul 26, 2025

DoubleTree by Hilton Gainesville
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area

2 out of 5
4202 SW 40th Blvd, Gainesville, FL
  • 23 min drive from Santa Fe Lake
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7/10 Good! (1,009 reviews)
"Just fine"

Reviewed on Jul 22, 2025

Super 8 by Wyndham Gainesville I-75 Hospital University Area
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 out of 5
4110 SW 40th Boulevard, Gainesville, FL
  • 23 min drive from Santa Fe Lake
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,020 reviews)
"Location and nearby amenities are great and the property itself is good. However, the elevator needs to be properly maintained and cleaned. Breakfast is wonderful and the staff is excellent, professional and friendly."

Reviewed on Jul 27, 2025

Sleep Inn & Suites University/Shands
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Melrose

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How many hotels are there in Melrose?

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Finding a cheap car rental deal in Melrose is as easy as scoring cheap hotels in Melrose. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.