Search Deals onMayesville Vacation Packages
Mayesville Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.

Studio 6 Florence , SC
Price was $692, price is now $670 per person
$670
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this motel in Florence. Enjoy free WiFi, a 24-hour front desk, and a snack bar/deli. Popular attractions Dr. Eddie Floyd Tennis Center and CarolinaBank Field are located nearby.

The Inn at the Crossroads
Price was $1,063, price is now $981 per person
$981
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Lake City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Lynches Lake Historical Society and The Bean Market are located nearby.

TownePlace Suites by Marriott Florence
Price was $863, price is now $817 per person
$817
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Florence Veterans Park and Magnolia Mall are located nearby.

The Mantissa Hotel
Price was $979, price is now $934 per person
$934
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this hotel in Hartsville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Hartsville Museum and Center Theatre are located nearby.
We stayed for a wedding. The location is close to restaurants and local shops. Our room was spacious and the staff is friendly. We really enjoyed the rooftop bar!
Reviewed on Nov 8, 2026

Hyatt Place Florence Downtown
Price was $875, price is now $842 per person
$842
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Florence County Museum and FMU Performing Arts Center are located nearby.
Great location
Reviewed on Nov 8, 2026

Affordable Suites Florence
Price was $729, price is now $711 per person
$711
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Stay at this hotel in Florence. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Florence Veterans Park and Regal Swamp Fox are located nearby.

Staybridge Suites Florence - Civic Center by IHG
Price was $968, price is now $960 per person
$960
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Regal Swamp Fox and Florence Veterans Park are located nearby.

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Price was $888, price is now $882 per person
$882
per person
Dec 30 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Philadelphia (PHL) to Florence (FLO)
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Country Club of South Carolina and Eastern Carolina Agricultural Fairgrounds are located nearby.
Mayesville Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.



Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Tue, Jan 19 - Sat, Jan 30
DFW
Dallas-Fort Worth Intl.
FLO
Florence Regional
$321 Roundtrip, found 1 day ago
$321
Roundtrip
found 1 day ago

Tue, Jan 26 - Sat, Feb 13
MSP
Minneapolis - St. Paul Intl.
FLO
Florence Regional
$461 Roundtrip, found 23 hours ago
$461
Roundtrip
found 23 hours ago

Tue, Dec 22 - Wed, Jan 6
JFK
John F. Kennedy Intl.
FLO
Florence Regional
$486 Roundtrip, found 2 days ago
$486
Roundtrip
found 2 days ago

Thu, Dec 24 - Tue, Jan 5
LGA
LaGuardia
FLO
Florence Regional
$580 Roundtrip, found 1 day ago
$580
Roundtrip
found 1 day ago
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