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Mayesville

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Mayesville Flights as Low as $324

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to Mayesville

Fall in love at first flight with your vacation to Mayesville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mayesville on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Mayesville, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Mayesville

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mayesville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the FLO airport.

What is the cheapest month to fly to Mayesville?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mayesville are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Mayesville?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mayesville.

What airport is best to fly into Mayesville?

When you’re planning your trip to Mayesville, convenience is the name of the game. Luckily, Mayesville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Mayesville must-do list.

How much are flights to Mayesville?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mayesville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $324, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Mayesville?

The trick to saving a stack of cash on your flight to Mayesville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $324 right now, why wait?

Mayesville Flight Information
Destination airport
Florence Regional
Destination airport IATA code
FLO
Roundtrip price
$323

Last Minute Hotel Deals in Mayesville

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning

2.5 out of 5
2816 Paxville Highway Manning SC
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,002 reviews)
Yes

Reviewed on Jan 18, 2026

SureStay Hotel by Best Western Manning
Hyatt Place Sumter / Downtown

Hyatt Place Sumter / Downtown

3 out of 5
18 N Main St Sumter SC
Book a stay at this business-friendly hotel in Sumter. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (895 reviews)
.

Reviewed on Jan 20, 2026

Hyatt Place Sumter / Downtown
Woodspring Suites Sumter Near Shaw Afb

Woodspring Suites Sumter Near Shaw Afb

2.5 out of 5
2715 Broad Street Sumter SC
Stay at this hotel in Sumter. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Sumter Mall and Palmetto Park are located nearby.
8.2/10 Very Good! (152 reviews)
The room was nice and clean the hotel had a fresh scent all through the hallways I will be returning

Reviewed on Jan 17, 2026

Woodspring Suites Sumter Near Shaw Afb
Tru by Hilton Sumter

Tru by Hilton Sumter

2.5 out of 5
2607 Broad Street Sumter SC
Stay at this hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular ...
8.8/10 Excellent! (686 reviews)
Every thing was perfect.The only issue was the bed could have been a little softer, but overall excellent.

Reviewed on Jan 18, 2026

Tru by Hilton Sumter
Hampton Inn Manning

Hampton Inn Manning

2.5 out of 5
2822 Paxville Hwy Manning SC
Book a stay at this business-friendly hotel in Manning. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,000 reviews)
Comfortable beds with xtra pillows. Breakfast was great with large variety. Pleasant staff. Easy check in and out. Only issue I saw was window coverage needs to be updated in our room.

Reviewed on Jan 20, 2026

Hampton Inn Manning
Holiday Inn Express Sumter by IHG

Holiday Inn Express Sumter by IHG

2.5 out of 5
2490 Broad St Sumter SC
Book a stay at this business-friendly hotel in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.6/10 Excellent! (709 reviews)
The floor had a big yellow stain on it and the room smelled like cat. The receptionist stated that they dont allow animals. But we later saw a person with a dog. The room should have inspected and cleaned before we arrived.

Reviewed on Jan 2, 2026

Holiday Inn Express Sumter by IHG
1912 Bed and Breakfast

1912 Bed and Breakfast

3.5 out of 5
24 Warren St Sumter SC
Book a stay at this business-friendly B&B in Sumter. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (286 reviews)
Comfortable beautiful bed and breakfast

Reviewed on Dec 30, 2025

1912 Bed and Breakfast
Best Inn of Manning

Best Inn of Manning

2.5 out of 5
2825 Paxville Hwy Manning SC
Stay at this hotel in Manning. Enjoy free WiFi, free parking, and an outdoor pool.
7.8/10 Good! (13 reviews)
No complaints

Reviewed on Jan 20, 2026

Best Inn of Manning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.