Search Cheap Flights toMayesville
Search 400 airlines and 321,000 hotels worldwide.
Stop Planning & Start Exploring
FREE 24 hour cancellation on most flights
Mayesville Flights as Low as $289
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Cheap Flights to Mayesville
Fall in love at first flight with your vacation to Mayesville by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Mayesville on Hotwire, and you’ll be up, up, and on a getaway in no time.
Because once the wheels are down in Mayesville, the good times start rolling. So buckle up, you’re in for a fun ride.
Frequently Asked Questions About flights to Mayesville
Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Mayesville with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.
So all you have to worry about is where you’re headed after the FLO airport.
What is the cheapest month to fly to Mayesville?
Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Mayesville are in July, but when you book your flight on Hotwire, savings are always in season.
How many airlines fly to Mayesville?
Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Mayesville.
What airport is best to fly into Mayesville?
When you’re planning your trip to Mayesville, convenience is the name of the game. Luckily, Mayesville Florence Regional Airport is nearby so you can deplane and get going on checking off everything on your Mayesville must-do list.
How much are flights to Mayesville?
Got very cheap flights on your vacation itinerary? When you book your airline tickets to Mayesville on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $289, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.
How to get cheap flights to Mayesville?
The trick to saving a stack of cash on your flight to Mayesville? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $289 right now, why wait?
Destination airport | Florence Regional |
|---|---|
Destination airport IATA code | FLO |
Roundtrip price | $288 |
Last Minute Hotel Deals in Mayesville
SureStay Hotel by Best Western Manning
clean and nice place.
Reviewed on Apr 28, 2026
Woodspring Suites Sumter Near Shaw Afb
Will definitely be back! Full size fridge, microwave and cook top. Extremely well maintained and clean!!
Reviewed on Apr 28, 2026
Hyatt Place Sumter / Downtown
Everything thing was great.
Reviewed on Apr 11, 2026
Red Roof Inn Sumter
Yes
Reviewed on Apr 26, 2026
Baymont by Wyndham Manning
Beds are terrible
Reviewed on Apr 22, 2026
Hampton Inn Manning
Room had black paper over the windows and the door had a huge gap. The room had an odor.
Reviewed on Apr 24, 2026
Quality Inn Sumter near Shaw AFB
When we got there, we cancelled the reservation. The pictures on Hotel.com are not the same as the Hotel in person. We saw the rooms. They smelled so bad. I informed the desk clerk and showed him the pictures on Hotel.com. He said a third party put those pictures online. I said to him that is not ...
Reviewed on Apr 11, 2026
Comfort Suites Sumter near Shaw AFB
This property was okay, it does need some care and upgrades
Reviewed on Apr 28, 2026
Nearby Cities
Popular Flight Routes
- Atlanta to New York
- Detroit to Las Vegas
- Dallas to Atlanta
- Dallas to Yosemite National Park
- Toronto to Edmonton
- Chicago to Tulum
- Houston to Lake Tahoe
- Chicago to Las Vegas
- Dallas to Miami
- Dallas to Lake Tahoe
- New York to Miami
- New York to Las Vegas
- Miami to Atlanta
- Minneapolis St Paul to Fort Walton Beach Destin
- Dallas to Branson
- Cleveland to Vero Beach
- Managua to Miami
- Atlanta to Boston
- Austin to Tulum
- Calgary to Vancouver