Search for Cheap Deals on
Hotels in Mainz City Center

Check Last Minute Mainz City Center Hotel Deals

Tonight Dec 5 - Dec 6This weekend Dec 5 - Dec 7

Choose from 1194 Mainz City Center Hotel Deals

Leonardo Hotel Mainz

Leonardo Hotel Mainz

Augustusstrasse 6 Mainz RP
  • 15 min walk from Mainz Cathedral
Stay at this hotel in Mainz. Enjoy breakfast (surcharge), 24-hour room service, and a fitness center. Our guests praise the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (841 reviews)
Staff were friendly, checking in was quick. Hotel is in good nick, and in-room temperature control.

Reviewed on Nov 22, 2025

Leonardo Hotel Mainz
Sheraton Frankfurt Airport Hotel & Conference Center

Sheraton Frankfurt Airport Hotel & Conference Center

Flughafen Terminal 1 Frankfurt HE
  • 49 min drive from Mainz Cathedral
Book a stay at this family-friendly hotel in Frankfurt. Enjoy 3 restaurants, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (2,674 reviews)
Clean room and comfortable bed. Quick distance from the city center and very short distance to the international terminal. I will come back again when in Frankfurt

Reviewed on Dec 2, 2025

Sheraton Frankfurt Airport Hotel & Conference Center
Staycity Aparthotels, Frankfurt Airport

Staycity Aparthotels, Frankfurt Airport

Amelia-Mary-Earhart-Straße 9 Frankfurt
  • 53 min drive from Mainz Cathedral
Stay at this hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the helpful staff and the clean rooms in our ...
9/10 Wonderful! (1,062 reviews)
We came from little town of SC and we don’t have this fancy hotel around. Just to improve your service it would be nice just give us an instructions how to use the key. Apparently this key has to do a lot like using the elevator and turning on the lights when you come in, in the dark room. Thank ...

Reviewed on Dec 3, 2025

Staycity Aparthotels, Frankfurt Airport
Maritim Hotel Frankfurt

Maritim Hotel Frankfurt

Theodor-Heuss-Allee 3 Frankfurt HE
  • 1 hour drive from Mainz Cathedral
Book a stay at this spa hotel in Frankfurt. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the breakfast and the helpful staff in ...
8.2/10 Very Good! (1,023 reviews)
Staffs are competent and service was great but the room was dated and could use some modernisation. Although parking is not run by the hotel, the underground parking connected to the hotel is very expensive at EUR45/night. I was told that there is a free street parking near by and provided with the ...

Reviewed on Nov 28, 2025

Maritim Hotel Frankfurt
Hyatt Place Frankfurt Airport

Hyatt Place Frankfurt Airport

De-Saint-Exupéry-Straße 4 Frankfurt HE
  • 53 min drive from Mainz Cathedral
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9.2/10 Wonderful! (2,149 reviews)
Excellent. I had a 10 hour layover in Frankfurt. Arrived at the hotel at 11 AM. Anahitta, was so helpful. She gave me an early checkin and a great room. Slept, shower and took the metro to the city center to visit the Christmas market. 1 minute walk to and from the station. Checked out and only one ...

Reviewed on Dec 1, 2025

Hyatt Place Frankfurt Airport
Hilton Garden Inn Frankfurt Airport

Hilton Garden Inn Frankfurt Airport

The Squaire Frankfurt
  • 49 min drive from Mainz Cathedral
Book a stay at this spa hotel in Frankfurt. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (2,669 reviews)
OK

Reviewed on Dec 3, 2025

Hilton Garden Inn Frankfurt Airport
Steigenberger Airport Hotel Frankfurt

Steigenberger Airport Hotel Frankfurt

Unterschweinstiege 16 Frankfurt HE
  • 52 min drive from Mainz Cathedral
Book a stay at this spa hotel in Frankfurt. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the breakfast and the restaurant in our ...
8.8/10 Excellent! (2,298 reviews)
Very big hotel. Didn't have a restroom near the lobby. The room was pretty and very clean. The staff I spoke to were very nice.

Reviewed on Dec 3, 2025

Steigenberger Airport Hotel Frankfurt
Platzhirsch Living Hotel

Platzhirsch Living Hotel

Am Südpark 15 Kelsterbach HE
  • 43 min drive from Mainz Cathedral
Stay at this hotel in Kelsterbach. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Popular attractions Deutsche Bank Park and Hoechst Castle ...
9/10 Wonderful! (753 reviews)
Very clean and quiet Thanks

Reviewed on Dec 3, 2025

Platzhirsch Living Hotel
Scandic Frankfurt Museumsufer

Scandic Frankfurt Museumsufer

Wilhelm-Leuschner-Straße 44 Frankfurt HE
  • 1 hour drive from Mainz Cathedral
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (1,094 reviews)
Excellent stay in Frankfurt! What a well appointed, spacious room in a modern hotel. The bedding was extremely comfortable and it was walkable to Romerberg and restaurants. The staff are truly efficient and so helpful. Everyone from front desk and in the restaurant were so attentive, warm and accommodating. ...

Reviewed on Nov 25, 2025

Scandic Frankfurt Museumsufer
IntercityHotel Frankfurt Hauptbahnhof Süd

IntercityHotel Frankfurt Hauptbahnhof Süd

Mannheimer Str. 21 Frankfurt HE
  • 1 hour drive from Mainz Cathedral
Book a stay at this business-friendly hotel in Frankfurt. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,518 reviews)
clean , convenient for city and train

Reviewed on Dec 2, 2025

IntercityHotel Frankfurt Hauptbahnhof Süd
IntercityHotel Frankfurt Airport

IntercityHotel Frankfurt Airport

4 out of 5
Am Luftbruckendenkmal 1 Frankfurt HE
  • 52 min drive from Mainz Cathedral
Book a stay at this spa hotel in Frankfurt. Enjoy a full-service spa, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (1,014 reviews)
Wonderful as always!

Reviewed on Nov 29, 2025

IntercityHotel Frankfurt Airport
b'mine Frankfurt Airport

b'mine Frankfurt Airport

Georg-Baumgarten-Straße Frankfurt HE
  • 52 min drive from Mainz Cathedral
Book a stay at this spa hotel in Frankfurt. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,025 reviews)
The room was very clean. Shower was amazing. Breakfast delicious. I would come back and definitely recommend it to my family and friends. Walking distance from the Airport!

Reviewed on Nov 24, 2025

b'mine Frankfurt Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Mainz City Center

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mainz City Center hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mainz City Center.

Choosing the right hotel in Rhineland-Palatinate has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mainz City Center’s 1,194 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $77. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Mainz City Center hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mainz City Center. No matter your reason for visiting Mainz City Center, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mainz City Center hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mainz City Center for as low as $77.

How many hotels are there in Mainz City Center?

With over 1,194 hotels in Mainz City Center, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $77.

How to find cheap car rentals in Mainz City Center?

Finding a cheap car rental deal in Mainz City Center is as easy as scoring cheap hotels in Mainz City Center. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.