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Little Italy Vacations

Pack those stellar shades. We have Little Italy vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Little Italy – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Little Italy vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Little Italy

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Little Italy vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Little Italy well.

Little Italy Flight + Hotel packages

Top Hotel Deals

See all 1,601 Hotels in Little Italy
La Pensione Hotel

La Pensione Hotel

606 West Date Street, San Diego
    3.0 out of 5.0
     
     

    Located in Little Italy, this hotel is within a 15-minute walk of Museum of Contemporary Art San Diego and Maritime Museum of San Diego. USS Midway Museum and ...

    Hampton Inn San Diego Downtown

    Hampton Inn San Diego Downtown

    1531 Pacific Hwy, San Diego
      2.5 out of 5.0
       
       

      This hotel is in downtown San Diego, next to a San Diego Trolley stop and within one-half mile of the Maritime Museum of San Diego and the Museum of Contemporary ...

      Homewood Suites by Hilton San Diego Downtown/Bayside

      Homewood Suites by Hilton San Diego Downtown/Bayside

      2137 Pacific Highway, San Diego
        3.5 out of 5.0
         
         

        Located in Little Italy, this hotel is within 1 mi (2 km) of Port of San Diego, Maritime Museum of San Diego, and USS Midway Museum. Balboa Park and San Diego ...

        Harborview Inn & Suites San Diego Harbor

        Harborview Inn & Suites San Diego Harbor

        550 West Grape St, San Diego
          2.0 out of 5.0
           
           

          Harborview Inn & Suites San Diego Harbor is 2 blocks from the city's Little Italy neighborhood. San Diego Zoo is a 7-minute drive away, and the hotel is a 15-minute ...

          Urban Boutique Hotel

          Urban Boutique Hotel

          1654 Columbia Street, San Diego
            3.0 out of 5.0
             
             

            Located in Little Italy, this hotel is within a 15-minute walk of Museum of Contemporary Art San Diego and Maritime Museum of San Diego. USS Midway Museum and ...

            Urban Boutique Hotel$85

            Urban Boutique Hotel$85
            Marina Inn and Suites

            Marina Inn and Suites

            1943 Pacific Hwy, San Diego
              2.0 out of 5.0
               
               

              Located in Little Italy, this motel is within 1 mi (2 km) of Port of San Diego, Maritime Museum of San Diego, and USS Midway Museum. San Diego Convention Center ...

              Porto Vista Hotel

              Porto Vista Hotel

              1835 Columbia St, San Diego
                3.5 out of 5.0
                 
                 

                Located in Little Italy, this hotel is within 1 mi (2 km) of Museum of Contemporary Art San Diego, Maritime Museum of San Diego, and Port of San Diego. USS Midway ...

                Hilton Garden Inn San Diego Downtown/Bayside, CA

                Hilton Garden Inn San Diego Downtown/Bayside, CA

                2137 Pacific Highway, San Diego
                  3.5 out of 5.0
                   
                   

                  Located in Little Italy, this hotel is within 1 mi (2 km) of Port of San Diego, Maritime Museum of San Diego, and USS Midway Museum. Balboa Park and San Diego ...

                  Pacific Inn and Suites

                  Pacific Inn and Suites

                  1655 Pacific Hwy, San Diego
                    2.0 out of 5.0
                     
                     

                    This downtown San Diego hotel is less than a half-mile from the waterfront Maritime Museum and about 1 mile from the San Diego Convention Center and Petco Park. ...

                    Found Hotel San Diego

                    Found Hotel San Diego

                    505 West Grape Street, San Diego
                      2.5 out of 5.0
                       
                       

                      Located in Little Italy, this hotel is within 1 mi (2 km) of Museum of Contemporary Art San Diego, Maritime Museum of San Diego, and USS Midway Museum. Balboa ...

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.