Search for Cheap Deals on
Hotels in Panhandle Plains

Choose from 2355 Panhandle Plains Hotel Deals

The Cactus Cove Inn and Suites

The Cactus Cove Inn and Suites

2 out of 5
2501 E Interstate Dr Amarillo TX
  • 4 hours drive from Texas Tech University
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,502 reviews)
"We didn’t realize this was an event type of hotel. If I had children that I wanted to have run around in an enclosed safe space, maybe I would have liked it better. We were also over the bar and the live music paly d until midnight."

Reviewed on Jun 24, 2026

The Cactus Cove Inn and Suites
The Big Texan Motel

The Big Texan Motel

2.5 out of 5
7701 Interstate 40 Access Rd Amarillo TX
  • 4 hours drive from Texas Tech University
Stay at this motel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the restaurant in our reviews. Popular ...
9/10 Wonderful! (4,082 reviews)
"Run down, room smelled. Pool was dirty. Def not a well taken care of tourist trap. Thought I'd give it a chance, but def wont stay again. Not worth the price."

Reviewed on Jun 25, 2026

The Big Texan Motel
Ashmore Inn and Suites

Ashmore Inn and Suites

2.5 out of 5
4019 S Loop 289 Lubbock TX
  • 9 min drive from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.6/10 Good! (1,714 reviews)
"The room was not clean. Cigarette ashes in several places. Furniture was in bad shape. Found lodging elsewhere."

Reviewed on Jun 25, 2026

Ashmore Inn and Suites
La Quinta Inn & Suites by Wyndham Lubbock Southwest

La Quinta Inn & Suites by Wyndham Lubbock Southwest

3 out of 5
6401 62nd Street Lubbock TX
  • 11 min drive from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (2,052 reviews)
"Front office staff was super nice and friendly. The hallway doors need better vacuuming. The closet had little kids underwear. The fan in our room sounded like it was about to explode. Breakfast was very sloppy, minimal effort was put in. The coffee was good though."

Reviewed on Jun 25, 2026

La Quinta Inn & Suites by Wyndham Lubbock Southwest
Fifth Season Suites

Fifth Season Suites

2 out of 5
6801 Interstate 40 West Amarillo TX
  • 4 hours drive from Texas Tech University
Stay at this hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cadillac Ranch and Westgate Mall are located ...
7.4/10 Good! (584 reviews)
"."

Reviewed on Jun 24, 2026

Fifth Season Suites
Overton Hotel and Conference Center

Overton Hotel and Conference Center

4 out of 5
2322 Mac Davis Ln Lubbock TX
  • 13 min walk from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
9/10 Wonderful! (1,113 reviews)
"Loved it and everyone was so friendly."

Reviewed on Jun 25, 2026

Overton Hotel and Conference Center
Microtel Inn & Suites By Wyndham Amarillo West

Microtel Inn & Suites By Wyndham Amarillo West

2.5 out of 5
2302 S. Soncy Road Amarillo TX
  • 4 hours drive from Texas Tech University
Stay at this hotel in Amarillo. Enjoy free breakfast, free parking, and a 24-hour front desk. Popular attractions Cadillac Ranch and Shops At Soncy are located ...
8.6/10 Excellent! (854 reviews)
"Overall stay was okay. The shower was dirty. Also the bed had what felt like sand under the main blanket so I went ahead and just slept on top of the blanket. Front desk staff was nice."

Reviewed on Jun 25, 2026

Microtel Inn & Suites By Wyndham Amarillo West
La Quinta Inn & Suites by Wyndham Lubbock South

La Quinta Inn & Suites by Wyndham Lubbock South

3 out of 5
6504 I-27 Lubbock TX
  • 8 min drive from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,418 reviews)
"Very clean and nice hotel! Would definitely book again. Great rates"

Reviewed on Jun 24, 2026

La Quinta Inn & Suites by Wyndham Lubbock South
Cotton Court, by Valencia Hotel Collection

Cotton Court, by Valencia Hotel Collection

4 out of 5
1610 Broadway St Lubbock TX
  • 17 min walk from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
9.6/10 Exceptional! (1,200 reviews)
"Cute place. Comfortable. Great stay"

Reviewed on Jun 23, 2026

Cotton Court, by Valencia Hotel Collection
Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr

Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr

3 out of 5
5214 2nd Dr Lubbock TX
  • 6 min drive from Texas Tech University
Book a stay at this business-friendly hotel in Lubbock. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.4/10 Very Good! (1,547 reviews)
"Good. Pool, breakfast, bed."

Reviewed on Jun 25, 2026

Wingate by Wyndham Lubbock near Texas Tech Univ. Medical Ctr
Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo

3 out of 5
8540 W Interstate 40 Amarillo TX
  • 4 hours drive from Texas Tech University
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Drury Inn & Suites Amarillo
Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG

2.5 out of 5
8330 W Amarillo Blvd Amarillo TX
  • 4 hours drive from Texas Tech University
Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (2,224 reviews)
"Hard to get to"

Reviewed on Jun 25, 2026

Holiday Inn Express & Suites Amarillo West by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Panhandle Plains

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Panhandle Plains hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Panhandle Plains.

Choosing the right hotel in Texas has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Panhandle Plains’s 2,355 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Panhandle Plains hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Panhandle Plains. No matter your reason for visiting Panhandle Plains, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Panhandle Plains hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Panhandle Plains for as low as $69.

How many hotels are there in Panhandle Plains?

With over 2,355 hotels in Panhandle Plains, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

How to find cheap car rentals in Panhandle Plains?

Finding a cheap car rental deal in Panhandle Plains is as easy as scoring cheap hotels in Panhandle Plains. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.