Search for Cheap Deals on
Hotels in Central Missouri

Choose from 4629 Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lodge Of Four Seasons Golf Resort, Marina & Spa
4 out of 5
315 Four Seasons Dr., Lake Ozark, MO
  • 20 min drive from Lake of the Ozarks
Stay at this 4-star beach resort in Lake Ozark. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the pool and the helpful staff in ...
7.2/10 Good! (1,009 reviews)
"Views"

Reviewed on Jun 29, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa
Baymont by Wyndham Columbia, MO
Baymont by Wyndham Columbia, MO
2.5 out of 5
2500 I 70 Dr Sw, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
7.8/10 Good! (316 reviews)
Okay
"Good stay but the “hot” breakfast was cold!! Our check in ahead to save time ended up taking more time."

Reviewed on Jun 29, 2025

Baymont by Wyndham Columbia, MO
Inn at Grand Glaize
Inn at Grand Glaize
2 out of 5
5142 Osage Beach Pkwy, Osage Beach, MO
  • 24 min drive from Lake of the Ozarks
Book a stay at this golf hotel in Osage Beach. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (133 reviews)
"The hotel staff was great. The hotel is old with some updates. Still needs lots of updates out sliding door did not lock"

Reviewed on Jun 27, 2025

Inn at Grand Glaize
Margaritaville Lake Resort Lake of the Ozarks
Margaritaville Lake Resort Lake of the Ozarks
3 out of 5
494 Tan Tar A Drive, Osage Beach, MO
  • 14 min drive from Lake of the Ozarks
Stay at this 3-star spa resort in Osage Beach. Enjoy free WiFi, free parking, and 3 outdoor pools. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,002 reviews)
"It was a nice weekend away . We did come across some rude employees throughout but outside of that it was pleasant ."

Reviewed on Jun 22, 2025

Margaritaville Lake Resort Lake of the Ozarks
Wingate by Wyndham - Columbia
Wingate by Wyndham - Columbia
3 out of 5
3101 Wingate Ct, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,107 reviews)
Nice hotel
"It was a great, clean basic hotel. Breakfast was great!"

Reviewed on Jun 29, 2025

Wingate by Wyndham - Columbia
Country Inn & Suites by Radisson, Columbia, MO
Country Inn & Suites by Radisson, Columbia, MO
2.5 out of 5
817 N Keene St, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,512 reviews)
"Room was great and spacious. A great nights sleep while traveling with kids"

Reviewed on Jun 27, 2025

Country Inn & Suites by Radisson, Columbia, MO
Drury Plaza Hotel Columbia East
Drury Plaza Hotel Columbia East
3 out of 5
3100 Interstate 70 Dr. SE, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3-star business-friendly hotel in Columbia. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and ...
9.6/10 Exceptional! (1,169 reviews)
A surprise!
"We booked last minute and were completely surprised by the amenities and “extras” offered….the staff were friendly and helpful, check-in quick, the room comfortable, gym was excellent…I come through Colombia a couple of times per year and will be booking a stay here!"

Reviewed on Jun 30, 2025

Drury Plaza Hotel Columbia East
Osage Village Inn
Osage Village Inn
2.5 out of 5
4616 Osage Beach Parkway, Osage Beach, MO
  • 27 min drive from Lake of the Ozarks
Stay at this hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.8/10 (971 reviews)
"Cool stay! Great jacuzzi. Wish there was a microwave in the rooms"

Reviewed on Jun 22, 2025

Osage Village Inn
Wyndham Executive Center Columbia
Wyndham Executive Center Columbia
3.5 out of 5
2200 I-70 Drive SW, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Stay at this 3.5-star business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,004 reviews)
"Getting there was confusing because GPS led is too the entrance of the Convention Center(?) Instead of the hotel lobby. However, We absolutely LOVED the Dove products supplied in the room."

Reviewed on Jun 29, 2025

Wyndham Executive Center Columbia
Baymont by Wyndham Osage Beach
Baymont by Wyndham Osage Beach
2.5 out of 5
5887 Osage Beach Pkwy, Osage Beach, MO
  • 20 min drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Osage Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms and the property ...
6.6/10 (1,000 reviews)
"Our first room was already occupied, so we had to go back to the front desk to get another one. Front desk staff wasn't available the two times I had questions and the phone number didn't work the first day I was there. The indoor pool is good, and the new room was adequate. Could be worse, could ..."

Reviewed on Jun 22, 2025

Baymont by Wyndham Osage Beach
Stoney Creek Hotel Columbia
Stoney Creek Hotel Columbia
2.5 out of 5
2601 S Providence Rd, Columbia, MO
  • 2 hours drive from Lake of the Ozarks
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the breakfast and the pool in ...
8.6/10 Excellent! (1,263 reviews)
"This was a great place to stay. The only thing I would recommend is changing the king mattress. Everything else was great. 200 yards from Venice Beach. We are actually from Sarasota and would recommend this property to anyone. Cheers"

Reviewed on Jun 26, 2025

Stoney Creek Hotel Columbia
The Resort at Lake of the Ozarks
The Resort at Lake of the Ozarks
3 out of 5
3080 Bagnell Dam Blvd, Lake Ozark, MO
  • 29 min drive from Lake of the Ozarks
Stay at this 3-star golf resort in Lake Ozark. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the bar in our reviews. Popular ...
8/10 Very Good! (456 reviews)
"Fun place. Favorite was bands and adult pool Least favorite our room only because it was old but it was nice and clean"

Reviewed on Jun 25, 2025

The Resort at Lake of the Ozarks
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Central Missouri

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Central Missouri hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Central Missouri.

Choosing the right hotel in Missouri has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Central Missouri’s 4,629 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as . In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Central Missouri hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Central Missouri. No matter your reason for visiting Central Missouri, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Central Missouri hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Central Missouri for as low as .

How many hotels are there in Central Missouri?

With over 4,629 hotels in Central Missouri, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as .

How to find cheap car rentals in Central Missouri?

Finding a cheap car rental deal in Central Missouri is as easy as scoring cheap hotels in Central Missouri. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.