Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Hotels in Central Missouri

See all 512 Properties in Central Missouri
Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr., Lake Ozark
    4.0 out of 5.0
     
     

    Located in Lake Ozark, this beachfront resort is connected to the convention center, 4.2 mi (6.8 km) from Bagnell Dam, and 8.2 mi (13.2 km) from Osage Beach ...

    Lodge Of Four Seasons Golf Resort, Marina & Spa$111

    Lodge Of Four Seasons Golf Resort, Marina & Spa$111
    Country Inn & Suites by Radisson, Columbia, MO

    Country Inn & Suites by Radisson, Columbia, MO

    817 N Keene St, Columbia
      2.5 out of 5.0
       
       

      Situated in Columbia, this hotel is 2.7 mi (4.3 km) from Stephens College and 2.9 mi (4.7 km) from Columbia College. University of Missouri and Museum of Art ...

      Country Inn & Suites by Radisson, Columbia, MO$76

      Country Inn & Suites by Radisson, Columbia, MO$76
      Ramada by Wyndham Columbia

      Ramada by Wyndham Columbia

      901 Conley Rd, Columbia
        2.5 out of 5.0
         
         

        Situated in Columbia, this hotel is 2.4 mi (3.8 km) from Stephens College and 2.7 mi (4.3 km) from Columbia College. University of Missouri is 2.9 mi (4.6 km) ...

        Ramada by Wyndham Columbia$51

        Ramada by Wyndham Columbia$51
        Wingate by Wyndham - Columbia

        Wingate by Wyndham - Columbia

        3101 Wingate Ct, Columbia
          3.0 out of 5.0
           
           

          Situated in Columbia, this hotel is 2.6 mi (4.1 km) from Stephens College and 3.1 mi (4.9 km) from University of Missouri. Columbia College and Museum of Art ...

          Wingate by Wyndham - Columbia$94

          Wingate by Wyndham - Columbia$94
          Baymont by Wyndham Jefferson City

          Baymont by Wyndham Jefferson City

          319 W. Miller Street, Jefferson City
            3.0 out of 5.0
             
             

            Located in the heart of Jefferson City, this hotel is within a 15-minute walk of Missouri State Capitol, Cole County Historical Society, and The Missouri Governor´s ...

            Baymont by Wyndham Jefferson City$65

            Baymont by Wyndham Jefferson City$65
            La Quinta Inn & Suites Columbia

            La Quinta Inn & Suites Columbia

            2500 I 70 Dr Sw, Columbia
              2.5 out of 5.0
               
               

              Situated in Columbia, this hotel is within 1 mi (2 km) of Columbia Mall and Shelter Gardens. Museum of Anthropology and Daniel Boone Regional Library are also ...

              La Quinta Inn & Suites Columbia$55

              La Quinta Inn & Suites Columbia$55
              Days Inn by Wyndham Jefferson City

              Days Inn by Wyndham Jefferson City

              2100 Jefferson St, Jefferson City
                2.0 out of 5.0
                 
                 

                Situated in Jefferson City, this hotel is 1.2 mi (2 km) from Oak Hills Golf Center and within 3 mi (5 km) of Lincoln University of Missouri and Missouri State ...

                Days Inn by Wyndham Jefferson City$47

                Days Inn by Wyndham Jefferson City$47
                The Lodge at Port Arrowhead

                The Lodge at Port Arrowhead

                3080 Bagnell Dam Blvd, Lake Ozark
                  2.5 out of 5.0
                   
                   

                  Situated in Lake Ozark, this hotel is 2.6 mi (4.1 km) from Bagnell Dam and 3.7 mi (6 km) from Osage Beach Premium Outlets. Lake of the Ozarks and Ozarks Caverns ...

                  The Lodge at Port Arrowhead$124

                  The Lodge at Port Arrowhead$124
                  Days Inn by Wyndham Boonville

                  Days Inn by Wyndham Boonville

                  2401 Pioneer St, Boonville
                    2.0 out of 5.0
                     
                     

                    Situated in Boonville, this hotel is 2.5 mi (4 km) from Lions Park Aquatic Center and within 6 mi (10 km) of Hail Ridge Golf Course and Harley Park. Boonslick ...

                    Days Inn by Wyndham Boonville$51

                    Days Inn by Wyndham Boonville$51
                    Days Inn by Wyndham Osage Beach Lake of the Ozarks

                    Days Inn by Wyndham Osage Beach Lake of the Ozarks

                    4755 Osage Beach Parkway, Osage Beach
                      2.0 out of 5.0
                       
                       

                      Located in the heart of Osage Beach, this hotel is 0.5 mi (0.8 km) from Osage Beach Premium Outlets and 16.2 mi (26 km) from Bridal Cave.

                      Days Inn by Wyndham Osage Beach Lake of the Ozarks$76

                      Days Inn by Wyndham Osage Beach Lake of the Ozarks$76
                      Map

                      Central Missouri Hotel Guide

                      Search for hotels in Central Missouri on Hotwire. Finding hotels in Central Missouri using one of the methods below, is simple and quick:

                      • Look through our selection of featured hotels in Central Missouri and check into the different facilities they offer
                      • Use the map to find hotels in the Central Missouri areas you prefer or hotels nearest to tourist attractions you plan to visit
                      • Use the filters to see hotels in a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Central Missouri
                      • Or just enter your travel dates to view the best deals on hotels in Central Missouri - while they last.