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Southwest Illinois

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Southwest Illinois Flights as Low as $229

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Bargain Flight
Fri, Oct 30 - Tue, Nov 3
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Oct 30 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Nov 3, priced at $229 found 1 day ago
Frontier Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$242 Roundtrip, found 8 hours ago
$242
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $242 found 8 hours ago
American Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$252 Roundtrip, found 8 hours ago
$252
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $252 found 8 hours ago
Delta
Fri, Oct 30 - Tue, Nov 3
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$255 Roundtrip, found 1 day ago
$255
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 30 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Nov 3, priced at $255 found 1 day ago
Frontier Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$256 Roundtrip, found 8 hours ago
$256
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $256 found 8 hours ago
Delta
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$262 Roundtrip, found 8 hours ago
$262
Roundtrip
found 8 hours ago
Select Delta flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $262 found 8 hours ago
Bargain Flight
Mon, Aug 10 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$265 Roundtrip, found 2 days ago
$265
Roundtrip
found 2 days ago
Select Bargain Flight flight, departing Mon, Aug 10 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $265 found 2 days ago
Bargain Flight
Sat, Jul 4 - Tue, Jul 28
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$267 Roundtrip, found 14 hours ago
$267
Roundtrip
found 14 hours ago
Select Bargain Flight flight, departing Sat, Jul 4 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Tue, Jul 28, priced at $267 found 14 hours ago
Frontier Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$273 Roundtrip, found 8 hours ago
$273
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $273 found 8 hours ago
American Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$277 Roundtrip, found 8 hours ago
$277
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $277 found 8 hours ago
Frontier Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$278 Roundtrip, found 8 hours ago
$278
Roundtrip
found 8 hours ago
Select Frontier Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $278 found 8 hours ago
Delta
Fri, Oct 30 - Tue, Nov 3
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Oct 30 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Nov 3, priced at $280 found 1 day ago
Frontier Airlines
Thu, Jul 30 - Sat, Aug 8
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$283 Roundtrip, found 3 days ago
$283
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Thu, Jul 30 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Sat, Aug 8, priced at $283 found 3 days ago
Alaska Airlines
Tue, Aug 11 - Thu, Aug 20
PHX
Sky Harbor Intl.
STL
Lambert-St. Louis Intl.
$533 Roundtrip, found 8 hours ago
$533
Roundtrip
found 8 hours ago
Select Alaska Airlines flight, departing Tue, Aug 11 from Sky Harbor Intl. to Lambert-St. Louis Intl., returning Thu, Aug 20, priced at $533 found 8 hours ago
American Airlines
Tue, Jun 23 - Sun, Jun 28
PHX
Sky Harbor Intl.
MWA
Veterans Airport of Southern Illinois
$651 Roundtrip, found 2 hours ago
$651
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Jun 23 from Sky Harbor Intl. to Veterans Airport of Southern Illinois, returning Sun, Jun 28, priced at $651 found 2 hours ago
American Airlines
Sun, Jul 5 - Mon, Jul 20
ORF
Norfolk Intl.
MWA
Veterans Airport of Southern Illinois
$713 Roundtrip, found 20 hours ago
$713
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Sun, Jul 5 from Norfolk Intl. to Veterans Airport of Southern Illinois, returning Mon, Jul 20, priced at $713 found 20 hours ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 13 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $229, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $229 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$67

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,717 reviews)
"I've stayed at this property probably 6-8 times and it's always a flawless stay. This last time, I was unhappy with my room due to the family next door and the noises from their children. I went downstairs and asked Kyleigh if there was another room available (30 minutes after I checked in). She ..."

Reviewed on Jun 8, 2026

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Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,016 reviews)
"Totally messed up my reservation. We reserved for two rooms only received one. My friend had to go and reserve a room for themselves. No one was willing to look into problem. Just blamed it on Hotels.com and advised I reserve direct with them next time. There will be no next time for this chain."

Reviewed on Jun 7, 2026

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Drury Inn & Suites St. Louis Fairview Heights
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,005 reviews)
"I checked into the room at 6pm and immediately noticed several large termites dead in the bathtub and a couple around the toilet, I turned on the water and washed them down. A couple hours later upon entering the bathroom there were several more of them in the tub yet again. I proceeded to order ..."

Reviewed on Jun 6, 2026

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,013 reviews)
"Great one-night stay. Room was quiet, bed was comfortable, and"free" food was good. Would recommend!"

Reviewed on Jun 8, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,013 reviews)
"Quality hotel as always. Only issue i had was since I was over the eating area i heard every chair and table movement in the morning. The bed was very comfortable and room size was adequate."

Reviewed on Jun 7, 2026

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Drury Inn & Suites Marion
The Principal Hotel

The Principal Hotel

3.5 out of 5
310 S Main St Columbia IL
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Triple Lakes Golf Course and Eckert’s Millstadt Farm ...
9.6/10 Exceptional! (287 reviews)
"Cute hotel in a former school. Looks brand new. Bed was perfect with full size pillows. Everything was very clean. A/C was turned down too low when we arrived. Room was freezing! Room had extra pilliws and blankets in the closet! It’s the little things that make a stay special"

Reviewed on Jun 8, 2026

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The Principal Hotel
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr East St. Louis IL
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,004 reviews)
"The free breakfast was gone an hour before service was over. Disappointed because that was one reason we stayed there."

Reviewed on Jun 7, 2026

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Quality Inn & Suites near St. Louis and I-255
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
5.8/10 (272 reviews)
"1. I always do the book now and pay later so I know what I’m paying for when I get to the hotel 2. I called the hotel to make sure me arriving early the next morning was ok and they said yes and for some reason they checked me in and charged my card. 3. I wasn’t made aware of that til I went to cancel ..."

Reviewed on Jun 8, 2026

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Welcome Suites
See all 776 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.