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Southwest Illinois

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Southwest Illinois Flights as Low as $101

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Thu, Aug 6 - Tue, Aug 18
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$101 Roundtrip, found 2 days ago
$101
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Aug 6 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 18, priced at $101 found 2 days ago
Frontier Airlines
Wed, Aug 5 - Mon, Aug 10
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$150 Roundtrip, found 4 hours ago
$150
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Wed, Aug 5 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Aug 10, priced at $150 found 4 hours ago
Frontier Airlines
Tue, Aug 4 - Mon, Aug 10
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$154 Roundtrip, found 4 hours ago
$154
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Tue, Aug 4 from Denver Intl. to Lambert-St. Louis Intl., returning Mon, Aug 10, priced at $154 found 4 hours ago
Frontier Airlines
Wed, Aug 5 - Wed, Aug 12
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$157 Roundtrip, found 4 hours ago
$157
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Wed, Aug 5 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $157 found 4 hours ago
Frontier Airlines
Tue, Aug 4 - Wed, Aug 12
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$161 Roundtrip, found 4 hours ago
$161
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Tue, Aug 4 from Denver Intl. to Lambert-St. Louis Intl., returning Wed, Aug 12, priced at $161 found 4 hours ago
Frontier Airlines
Tue, Jul 14 - Thu, Jul 16
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$162 Roundtrip, found 2 days ago
$162
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Tue, Jul 14 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Thu, Jul 16, priced at $162 found 2 days ago
Frontier Airlines
Sun, Aug 9 - Tue, Aug 11
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$165 Roundtrip, found 5 days ago
$165
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Sun, Aug 9 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $165 found 5 days ago
Frontier Airlines
Tue, Aug 4 - Tue, Aug 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$166 Roundtrip, found 4 hours ago
$166
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Tue, Aug 4 from Denver Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $166 found 4 hours ago
Frontier Airlines
Sat, Jun 20 - Wed, Jun 24
DFW
Dallas-Fort Worth Intl.
STL
Lambert-St. Louis Intl.
$167 Roundtrip, found 3 days ago
$167
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Jun 20 from Dallas-Fort Worth Intl. to Lambert-St. Louis Intl., returning Wed, Jun 24, priced at $167 found 3 days ago
Delta
Sat, Oct 17 - Tue, Oct 20
DAL
Love Field
STL
Lambert-St. Louis Intl.
$209 Roundtrip, found 1 hour ago
$209
Roundtrip
found 1 hour ago
Select Delta flight, departing Sat, Oct 17 from Love Field to Lambert-St. Louis Intl., returning Tue, Oct 20, priced at $209 found 1 hour ago
Delta
Sat, Oct 31 - Tue, Nov 3
ORF
Norfolk Intl.
STL
Lambert-St. Louis Intl.
$225 Roundtrip, found 21 hours ago
$225
Roundtrip
found 21 hours ago
Select Delta flight, departing Sat, Oct 31 from Norfolk Intl. to Lambert-St. Louis Intl., returning Tue, Nov 3, priced at $225 found 21 hours ago
United
Tue, Aug 4 - Tue, Aug 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$226 Roundtrip, found 4 hours ago
$226
Roundtrip
found 4 hours ago
Select United flight, departing Tue, Aug 4 from Denver Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $226 found 4 hours ago
American Airlines
Tue, Aug 4 - Tue, Aug 11
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$246 Roundtrip, found 4 hours ago
$246
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Tue, Aug 4 from Denver Intl. to Lambert-St. Louis Intl., returning Tue, Aug 11, priced at $246 found 4 hours ago
United
Thu, Sep 3 - Sun, Sep 13
DFW
Dallas-Fort Worth Intl.
PAH
Barkley Regional
$298 Roundtrip, found 5 days ago
$298
Roundtrip
found 5 days ago
Select United flight, departing Thu, Sep 3 from Dallas-Fort Worth Intl. to Barkley Regional, returning Sun, Sep 13, priced at $298 found 5 days ago
American Airlines
Wed, Jul 8 - Wed, Jul 22
ORF
Norfolk Intl.
MWA
Veterans Airport of Southern Illinois
$624 Roundtrip, found 16 hours ago
$624
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Wed, Jul 8 from Norfolk Intl. to Veterans Airport of Southern Illinois, returning Wed, Jul 22, priced at $624 found 16 hours ago
Alaska Airlines
Sun, Jul 26 - Fri, Jul 31
DEN
Denver Intl.
STL
Lambert-St. Louis Intl.
$878 Roundtrip, found 2 days ago
$878
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Sun, Jul 26 from Denver Intl. to Lambert-St. Louis Intl., returning Fri, Jul 31, priced at $878 found 2 days ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $101, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $101 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$100

Last Minute Hotel Deals in Southwest Illinois

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,722 reviews)
"Everything was clean and well kept. Room was really comfortable. Breakfast was great."

Reviewed on Jun 10, 2026

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Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,017 reviews)
"It was a simple stay, I didn’t spend much time at the hotel but they were quick with no issues. I might have left my white button up in the closet. But overall everything was fine."

Reviewed on Jun 9, 2026

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Drury Inn & Suites St. Louis Fairview Heights
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,004 reviews)
"I checked into the room at 6pm and immediately noticed several large termites dead in the bathtub and a couple around the toilet, I turned on the water and washed them down. A couple hours later upon entering the bathroom there were several more of them in the tub yet again. I proceeded to order ..."

Reviewed on Jun 6, 2026

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,001 reviews)
"Great one-night stay. Room was quiet, bed was comfortable, and"free" food was good. Would recommend!"

Reviewed on Jun 8, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,013 reviews)
"Quality hotel as always. Only issue i had was since I was over the eating area i heard every chair and table movement in the morning. The bed was very comfortable and room size was adequate."

Reviewed on Jun 7, 2026

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Drury Inn & Suites Marion
The Principal Hotel

The Principal Hotel

3.5 out of 5
310 S Main St Columbia IL
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Triple Lakes Golf Course and Eckert’s Millstadt Farm ...
9.6/10 Exceptional! (288 reviews)
"Cute hotel in a former school. Looks brand new. Bed was perfect with full size pillows. Everything was very clean. A/C was turned down too low when we arrived. Room was freezing! Room had extra pilliws and blankets in the closet! It’s the little things that make a stay special"

Reviewed on Jun 8, 2026

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The Principal Hotel
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr East St. Louis IL
Book a stay at this business-friendly hotel in East St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,006 reviews)
"We booked this hotel as out of town guests visiting St. Louis. Had no idea where we were staying. #1 it's in the ghetto. Bad roads literally and physically. #2 smells like pot. People was smoking pot and cigarettes just outside the front door. #3 We were charged a $100 incidental fee which still ..."

Reviewed on Jun 9, 2026

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Quality Inn & Suites near St. Louis and I-255
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
5.8/10 (273 reviews)
"1. I always do the book now and pay later so I know what I’m paying for when I get to the hotel 2. I called the hotel to make sure me arriving early the next morning was ok and they said yes and for some reason they checked me in and charged my card. 3. I wasn’t made aware of that til I went to cancel ..."

Reviewed on Jun 8, 2026

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Welcome Suites
See all 776 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.