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Southwest Illinois

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Southwest Illinois Flights as Low as $66

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Aug 12 - Sat, Aug 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$66 Roundtrip, just found
$66
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 22, priced at $66 just found
Frontier Airlines
Tue, Jul 14 - Tue, Jul 14
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$68 Roundtrip, found 9 hours ago
$68
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Tue, Jul 14 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Jul 14, priced at $68 found 9 hours ago
Frontier Airlines
Mon, Jul 6 - Wed, Jul 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$77 Roundtrip, found 12 hours ago
$77
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Mon, Jul 6 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Jul 22, priced at $77 found 12 hours ago
Frontier Airlines
Wed, Jul 8 - Sun, Jul 26
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$79 Roundtrip, found 1 hour ago
$79
Roundtrip
found 1 hour ago
Select Frontier Airlines flight, departing Wed, Jul 8 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sun, Jul 26, priced at $79 found 1 hour ago
Frontier Airlines
Wed, Jun 24 - Wed, Jul 1
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$84 Roundtrip, just found
$84
Roundtrip
just found
Select Frontier Airlines flight, departing Wed, Jun 24 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Wed, Jul 1, priced at $84 just found
Frontier Airlines
Mon, Aug 10 - Sat, Aug 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$87 Roundtrip, found 4 hours ago
$87
Roundtrip
found 4 hours ago
Select Frontier Airlines flight, departing Mon, Aug 10 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 22, priced at $87 found 4 hours ago
Frontier Airlines
Tue, Jun 23 - Tue, Jun 23
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$90 Roundtrip, found 22 hours ago
$90
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Tue, Jun 23 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Jun 23, priced at $90 found 22 hours ago
Delta
Wed, Aug 12 - Sat, Aug 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$92 Roundtrip, just found
$92
Roundtrip
just found
Select Delta flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 22, priced at $92 just found
Frontier Airlines
Tue, Jun 23 - Mon, Jun 29
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$96 Roundtrip, found 2 days ago
$96
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Tue, Jun 23 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Mon, Jun 29, priced at $96 found 2 days ago
Delta
Wed, Aug 12 - Tue, Aug 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$97 Roundtrip, found 4 hours ago
$97
Roundtrip
found 4 hours ago
Select Delta flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $97 found 4 hours ago
Delta
Wed, Aug 12 - Sat, Aug 22
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$117 Roundtrip, just found
$117
Roundtrip
just found
Select Delta flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Sat, Aug 22, priced at $117 just found
American Airlines
Wed, Aug 12 - Tue, Aug 25
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$257 Roundtrip, found 4 hours ago
$257
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Aug 12 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Aug 25, priced at $257 found 4 hours ago
Delta
Sat, Oct 17 - Tue, Oct 20
DAL
Love Field
STL
Lambert-St. Louis Intl.
$263 Roundtrip, found 9 hours ago
$263
Roundtrip
found 9 hours ago
Select Delta flight, departing Sat, Oct 17 from Love Field to Lambert-St. Louis Intl., returning Tue, Oct 20, priced at $263 found 9 hours ago
Bargain Flight
Sat, Jun 13 - Tue, Jun 16
ATL
Hartsfield-Jackson Atlanta Intl.
STL
Lambert-St. Louis Intl.
$263 Roundtrip, found 18 hours ago
$263
Roundtrip
found 18 hours ago
Select Bargain Flight flight, departing Sat, Jun 13 from Hartsfield-Jackson Atlanta Intl. to Lambert-St. Louis Intl., returning Tue, Jun 16, priced at $263 found 18 hours ago
Delta
Sat, Sep 5 - Tue, Sep 22
EYW
Key West Intl.
STL
Lambert-St. Louis Intl.
$298 Roundtrip, found 6 hours ago
$298
Roundtrip
found 6 hours ago
Select Delta flight, departing Sat, Sep 5 from Key West Intl. to Lambert-St. Louis Intl., returning Tue, Sep 22, priced at $298 found 6 hours ago
United
Wed, Jun 10 - Thu, Jun 18
ATL
Hartsfield-Jackson Atlanta Intl.
PAH
Barkley Regional
$564 Roundtrip, found 2 days ago
$564
Roundtrip
found 2 days ago
Select United flight, departing Wed, Jun 10 from Hartsfield-Jackson Atlanta Intl. to Barkley Regional, returning Thu, Jun 18, priced at $564 found 2 days ago

Cheap Flights to Southwest Illinois

Fall in love at first flight with your vacation to Southwest Illinois by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Southwest Illinois on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Southwest Illinois, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Southwest Illinois

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Southwest Illinois with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the STL airport.

What is the cheapest month to fly to Southwest Illinois?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Southwest Illinois are in August, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Southwest Illinois?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Southwest Illinois.

What airport is best to fly into Southwest Illinois?

When you’re planning your trip to Southwest Illinois, convenience is the name of the game. Luckily, Southwest Illinois Veterans Airport of Southern Illinois Airport is nearby so you can deplane and get going on checking off everything on your Southwest Illinois must-do list.

How much are flights to Southwest Illinois?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Southwest Illinois on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $66, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Southwest Illinois?

The trick to saving a stack of cash on your flight to Southwest Illinois? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $66 right now, why wait?

Southwest Illinois Flight Information
Destination airport
Lambert-St. Louis Intl.
Destination airport IATA code
STL
Roundtrip price
$66

Last Minute Hotel Deals in Southwest Illinois

Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,007 reviews)
"Solid stay, no frills but no disappointment either"

Reviewed on Jun 4, 2026

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Drury Inn & Suites Marion
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Book a stay at this business-friendly hotel in Fairview Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,015 reviews)
"Our only complaint was the cleanliness of the pool and hot tub area. There were towels everywhere on the floor and there was a heavy thick white foam in the hot tub. Other than that the rooms are ok, bathrooms a little small but it's ok. Beds were comfortable and clean. Breakfast was good."

Reviewed on Jun 6, 2026

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Drury Inn & Suites St. Louis Fairview Heights
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Book a stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,712 reviews)
"Great hotel to stay in. Right off the interstate. Wonderful happy hour and breakfast. Would definitely stay again."

Reviewed on Jun 6, 2026

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Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,005 reviews)
"I checked into the room at 6pm and immediately noticed several large termites dead in the bathtub and a couple around the toilet, I turned on the water and washed them down. A couple hours later upon entering the bathroom there were several more of them in the tub yet again. I proceeded to order ..."

Reviewed on Jun 6, 2026

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Super 8 by Wyndham O'Fallon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

3 out of 5
1118 Central Park Drive O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,008 reviews)
"Great place. Our 2nd stay here. Staff are kind. Breakfast was good and the pool is cool."

Reviewed on Jun 6, 2026

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Drury Inn & Suites St. Louis O'Fallon, IL
The Principal Hotel

The Principal Hotel

3.5 out of 5
310 S Main St Columbia IL
Stay at this hotel in Columbia. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Triple Lakes Golf Course and Eckert’s Millstadt Farm ...
9.6/10 Exceptional! (282 reviews)
"Hotel was very clean and rooms were spacious.. staff was also very friendly. Only thing is I wished they had a pool."

Reviewed on Jun 6, 2026

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The Principal Hotel
Welcome Suites

Welcome Suites

2 out of 5
148 Regency Park O'Fallon IL
Book a stay at this business-friendly hotel in O'Fallon. Enjoy free WiFi, free parking, and a fitness center. Popular attractions O'Fallon Family Sports Park ...
5.8/10 (270 reviews)
"There was fighting in the halls and loud neighbors. My fridge didn't work all my food spoiled. They couldn't give me a remote that worked with the TV had to buy my own and program it. They kicked me out because I had my emotional support cats with me. Mind you I was suppose to be there 19 days and ..."

Reviewed on Jun 3, 2026

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Welcome Suites
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 out of 5
777 Walkers Bluff Way Carterville IL
Book a stay at this luxury resort in Carterville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (465 reviews)
"The pool and jacuzzi are amazing. The rooms are clean and very nice."

Reviewed on Jun 4, 2026

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Walker's Bluff Casino Resort
See all 766 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.