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La Mesa

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La Mesa Flights as Low as $56

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Tue, Jul 21 - Wed, Aug 5
SFO
San Francisco Intl.
SAN
San Diego Intl.
$56 Roundtrip, found 6 days ago
$56
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Tue, Jul 21 from San Francisco Intl. to San Diego Intl., returning Wed, Aug 5, priced at $56 found 6 days ago
Frontier Airlines
Sat, Jul 4 - Tue, Jul 14
SFO
San Francisco Intl.
SAN
San Diego Intl.
$58 Roundtrip, found 2 hours ago
$58
Roundtrip
found 2 hours ago
Select Frontier Airlines flight, departing Sat, Jul 4 from San Francisco Intl. to San Diego Intl., returning Tue, Jul 14, priced at $58 found 2 hours ago
Frontier Airlines
Tue, Jun 16 - Wed, Jun 24
SFO
San Francisco Intl.
SAN
San Diego Intl.
$77 Roundtrip, found 5 hours ago
$77
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Tue, Jun 16 from San Francisco Intl. to San Diego Intl., returning Wed, Jun 24, priced at $77 found 5 hours ago
Alaska Airlines
Tue, Jun 16 - Tue, Jun 16
SFO
San Francisco Intl.
SAN
San Diego Intl.
$137 Roundtrip, found 5 hours ago
$137
Roundtrip
found 5 hours ago
Select Alaska Airlines flight, departing Tue, Jun 16 from San Francisco Intl. to San Diego Intl., returning Tue, Jun 16, priced at $137 found 5 hours ago
United
Sat, Jul 4 - Tue, Jul 14
SFO
San Francisco Intl.
SAN
San Diego Intl.
$140 Roundtrip, found 2 hours ago
$140
Roundtrip
found 2 hours ago
Select United flight, departing Sat, Jul 4 from San Francisco Intl. to San Diego Intl., returning Tue, Jul 14, priced at $140 found 2 hours ago
Delta
Tue, Jun 16 - Tue, Jun 16
SFO
San Francisco Intl.
SAN
San Diego Intl.
$157 Roundtrip, found 5 hours ago
$157
Roundtrip
found 5 hours ago
Select Delta flight, departing Tue, Jun 16 from San Francisco Intl. to San Diego Intl., returning Tue, Jun 16, priced at $157 found 5 hours ago
Frontier Airlines
Tue, Oct 13 - Tue, Oct 27
IAH
George Bush Intercontinental
SAN
San Diego Intl.
$230 Roundtrip, found 22 hours ago
$230
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Tue, Oct 13 from George Bush Intercontinental to San Diego Intl., returning Tue, Oct 27, priced at $230 found 22 hours ago
American Airlines
Tue, Jun 16 - Tue, Jun 16
SFO
San Francisco Intl.
SAN
San Diego Intl.
$242 Roundtrip, found 5 hours ago
$242
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Tue, Jun 16 from San Francisco Intl. to San Diego Intl., returning Tue, Jun 16, priced at $242 found 5 hours ago
Bargain Flight
Tue, Oct 27 - Tue, Nov 3
TPA
Tampa Intl.
SAN
San Diego Intl.
$270 Roundtrip, found 7 hours ago
$270
Roundtrip
found 7 hours ago
Select Bargain Flight flight, departing Tue, Oct 27 from Tampa Intl. to San Diego Intl., returning Tue, Nov 3, priced at $270 found 7 hours ago
United
Tue, Jun 2 - Wed, Jun 17
SFO
San Francisco Intl.
CLD
McClellan-Palomar
$270 Roundtrip, found 19 hours ago
$270
Roundtrip
found 19 hours ago
Select United flight, departing Tue, Jun 2 from San Francisco Intl. to McClellan-Palomar, returning Wed, Jun 17, priced at $270 found 19 hours ago
Delta
Tue, Jul 21 - Wed, Aug 5
TUL
Tulsa Intl.
SAN
San Diego Intl.
$319 Roundtrip, found 14 hours ago
$319
Roundtrip
found 14 hours ago
Select Delta flight, departing Tue, Jul 21 from Tulsa Intl. to San Diego Intl., returning Wed, Aug 5, priced at $319 found 14 hours ago
American Airlines
Tue, Oct 13 - Tue, Oct 27
IAH
George Bush Intercontinental
CLD
McClellan-Palomar
$329 Roundtrip, found 22 hours ago
$329
Roundtrip
found 22 hours ago
Select American Airlines flight, departing Tue, Oct 13 from George Bush Intercontinental to McClellan-Palomar, returning Tue, Oct 27, priced at $329 found 22 hours ago
United
Fri, Jul 17 - Mon, Jul 20
TUL
Tulsa Intl.
CLD
McClellan-Palomar
$419 Roundtrip, found 14 hours ago
$419
Roundtrip
found 14 hours ago
Select United flight, departing Fri, Jul 17 from Tulsa Intl. to McClellan-Palomar, returning Mon, Jul 20, priced at $419 found 14 hours ago
United
Tue, May 26 - Tue, Jun 9
TPA
Tampa Intl.
CLD
McClellan-Palomar
$449 Roundtrip, found 7 hours ago
$449
Roundtrip
found 7 hours ago
Select United flight, departing Tue, May 26 from Tampa Intl. to McClellan-Palomar, returning Tue, Jun 9, priced at $449 found 7 hours ago
Sun Country Airlines
Thu, Oct 22 - Sun, Nov 1
TPA
Tampa Intl.
SAN
San Diego Intl.
$453 Roundtrip, found 11 hours ago
$453
Roundtrip
found 11 hours ago
Select Sun Country Airlines flight, departing Thu, Oct 22 from Tampa Intl. to San Diego Intl., returning Sun, Nov 1, priced at $453 found 11 hours ago
JetBlue Airways
Fri, Jul 24 - Tue, Aug 4
TPA
Tampa Intl.
SAN
San Diego Intl.
$485 Roundtrip, found 1 hour ago
$485
Roundtrip
found 1 hour ago
Select JetBlue Airways flight, departing Fri, Jul 24 from Tampa Intl. to San Diego Intl., returning Tue, Aug 4, priced at $485 found 1 hour ago

Cheap Flights to La Mesa

Fall in love at first flight with your vacation to La Mesa by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to La Mesa on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in La Mesa, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to La Mesa

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to La Mesa with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SAN airport.

What is the cheapest month to fly to La Mesa?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to La Mesa are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to La Mesa?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to La Mesa.

What airport is best to fly into La Mesa?

When you’re planning your trip to La Mesa, convenience is the name of the game. Luckily, La Mesa Gillespie Field Airport is nearby so you can deplane and get going on checking off everything on your La Mesa must-do list.

How much are flights to La Mesa?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to La Mesa on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $56, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to La Mesa?

The trick to saving a stack of cash on your flight to La Mesa? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $56 right now, why wait?

La Mesa Flight Information
Destination airport
San Diego Intl.
Destination airport IATA code
SAN
Roundtrip price
$56

Last Minute Hotel Deals in La Mesa

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
Book a stay at this historic hotel in San Diego. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (2,055 reviews)
"It was an older hotel and it showed in places, but the staff were super friendly and the location was great."

Reviewed on May 17, 2026

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The Sofia Hotel
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,592 reviews)
"Great Family atmosphere. The food at both restaurants was excellent. Great spot to enjoy and if you have little ones great place to go to sea world and other locations in san diego. Very much recommend!"

Reviewed on May 18, 2026

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Paradise Point Resort & Spa
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
9/10 Wonderful! (2,837 reviews)
"Amazing property. A must visit for San Diego"

Reviewed on May 18, 2026

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Manchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (3,682 reviews)
"The front desk clerk neglected to inform us about the $150 per night incidental charges. It was a shock after we saw the charge getting to our room. There was an adult massager for sale with the mini bar that created an awkward situation with our young children! The room was very nice and the location ..."

Reviewed on May 18, 2026

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Hard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (1,587 reviews)
"The hotel in general wasn't bad, the staff was friendly, quick check in and out was easy and fast. Room was cozy. Bed was comfortable. Just a few blocks from Little Italy. I only have 2 complaints 1.) One out of the two elevators were working so the wait for the elevator was ridiculously long and ..."

Reviewed on May 18, 2026

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The DEXTRO Little Italy, BW Premier Collection
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,166 reviews)
"The property was clean. The room was clean with a nice view of the bay."

Reviewed on May 18, 2026

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Wyndham San Diego Bayside
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,509 reviews)
"Here’s a cleaner and more professional version of your review while still keeping your honest experience and concerns clear: The hotel is average overall, but considering how expensive hotels in San Diego County can be, I do think this is an affordable option for the price. I found the property to ..."

Reviewed on May 17, 2026

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Best Western Seven Seas
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,536 reviews)
"gym not clean"

Reviewed on May 18, 2026

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Handlery Hotel
See all 8,375 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.