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Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
  • 8 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7.6/10 Good! (575 reviews)
Staff is very polite and accommodating

Reviewed on Apr 28, 2026

Motel 6 West Columbia, SC - Airport
Quality Inn Columbia Airport

Quality Inn Columbia Airport

2.5 out of 5
2516 Augusta Rd West Columbia SC
  • 4 min drive from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
6.6/10 (1,001 reviews)
Yummy breakfast Clean and spacious room

Reviewed on Apr 30, 2026

Quality Inn Columbia Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Staff was very nice clean room kids wanted to swim poop was open but not they were told they can sit outside in pool area just hit get in other than that very nice clean place to stay I

Reviewed on Apr 22, 2026

Hilton Garden Inn Columbia Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,000 reviews)
The pictures online are not the same as when you are actually there. The rooms are out dated. The bed sheets had yellow stain and cigarette burns. The pillows were flat. The shower curtain was fabric and bottom of it was yellow. The continental breakfast was almost non exsisting. There was a mini ...

Reviewed on Apr 27, 2026

Clarion Inn Columbia Airport
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
  • 9 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.2/10 Very Good! (1,000 reviews)
Room was clean, breakfast was great, parking was easy and safe

Reviewed on Apr 27, 2026

Hampton Inn Columbia-I-26 Airport
Sleep Inn Columbia Airport

Sleep Inn Columbia Airport

2.5 out of 5
2208 A Edmund Hwy West Columbia SC
  • 9 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (865 reviews)
Stay was ok

Reviewed on Apr 27, 2026

Sleep Inn Columbia Airport
Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce

2.5 out of 5
3020 Charleston Hwy West Columbia SC
  • 14 min drive from Lexington Medical Center
Book a stay at this family-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (457 reviews)
Everything was good. I did have to wait a minute to check in. Other guests had not received their deposit back and was trying to get attendent to assist. I have not received my credit either for the $40 deposit to date.

Reviewed on Apr 29, 2026

Quality Inn West Columbia - Cayce
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

3 out of 5
122 Mathias Rd West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (376 reviews)
Breakfast was cold. The coffee was cold as well. 2nd morning was a little better

Reviewed on Apr 28, 2026

Residence Inn Columbia West/Lexington
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 15 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,032 reviews)
Yes

Reviewed on May 1, 2026

Hilton Garden Inn Columbia/Harbison
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,053 reviews)
Overall stay was good. Front desk and staff were nice folks. Hotel is outdated but kept well. Breakfast is fair but appreciated given the affordability of the stay. The only thing that was dissapointed was the toilet not flushing well.. Otherwise, this hotel is decent.

Reviewed on Apr 27, 2026

Sleep Inn Columbia
Courtyard by Marriott Columbia Downtown at USC

Courtyard by Marriott Columbia Downtown at USC

3 out of 5
630 Assembly St Columbia SC
  • 12 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,002 reviews)
We had no room service

Reviewed on Apr 26, 2026

Courtyard by Marriott Columbia Downtown at USC
Graduate by Hilton Columbia SC

Graduate by Hilton Columbia SC

4 out of 5
1619 Pendleton Street Columbia SC
  • 13 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.4/10 Exceptional! (1,002 reviews)
Always nice to stay at The Graduate in any college town I visit.

Reviewed on Apr 30, 2026

Graduate by Hilton Columbia SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in West Columbia

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $62. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great West Columbia hotel deals at the last minute.

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Frequently Asked Questions About West Columbia hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in West Columbia?

With over 1,099 hotels in West Columbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $62.

How to find cheap car rentals in West Columbia?

Finding a cheap car rental deal in West Columbia is as easy as scoring cheap hotels in West Columbia. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.