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Motel 6 West Columbia, SC - Airport

Motel 6 West Columbia, SC - Airport

2 out of 5
650 Cherokee Lane West Columbia SC
  • 8 min drive from Lexington Medical Center
Book a stay at this business-friendly motel in West Columbia. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...
7.6/10 Good! (537 reviews)
It was very nice and clean

Reviewed on Mar 26, 2026

Motel 6 West Columbia, SC - Airport
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

2.5 out of 5
1094 Chris Dr West Columbia SC
  • 9 min walk from Lexington Medical Center
Stay at this hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
Good breakfast, comfortable room, pleasant staff

Reviewed on Apr 1, 2026

Hampton Inn Columbia-I-26 Airport
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

2.5 out of 5
500 Chris Dr West Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,000 reviews)
Ironing board but no iron. I’m not sure if iron is available by checking it out. Conditioner was half used when we got there.

Reviewed on Mar 29, 2026

Clarion Inn Columbia Airport
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

3 out of 5
110 McSwain Drive West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,000 reviews)
Was very clean and quiet. Only complaint is the cost of food on site is high and the smoke alarm went off in morning. Elevators made me nervous and location isn't as good as i expected

Reviewed on Mar 29, 2026

Hilton Garden Inn Columbia Airport
Sleep Inn Columbia Airport

Sleep Inn Columbia Airport

2.5 out of 5
2208 A Edmund Hwy West Columbia SC
  • 9 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
7.8/10 Good! (854 reviews)
Good

Reviewed on Apr 2, 2026

Sleep Inn Columbia Airport
Quality Inn West Columbia - Cayce

Quality Inn West Columbia - Cayce

2.5 out of 5
3020 Charleston Hwy West Columbia SC
  • 14 min drive from Lexington Medical Center
Book a stay at this family-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7/10 Good! (444 reviews)
Breakfast was good. Staff were very nice. Easy parking.

Reviewed on Apr 2, 2026

Quality Inn West Columbia - Cayce
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

3 out of 5
122 Mathias Rd West Columbia SC
  • 6 min walk from Lexington Medical Center
Book a stay at this business-friendly hotel in West Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
Residence Inn Columbia West/Lexington
Hilton Garden Inn Columbia/Harbison

Hilton Garden Inn Columbia/Harbison

3 out of 5
434 Columbiana Dr Columbia SC
  • 15 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (2,000 reviews)
very disappointed, check in was supposed to be at 3pm and when we arrived at 4pm there was a line of people waiting on rooms and they told me they had no ETA of when my room would be read and to come back in a few hours and they would call me. They never called and I went back at 7pm and checked ...

Reviewed on Apr 3, 2026

Hilton Garden Inn Columbia/Harbison
Sleep Inn Columbia

Sleep Inn Columbia

2.5 out of 5
1901 Rockland Rd Columbia SC
  • 4 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,033 reviews)
Everything was good except for the terrible breakfast.

Reviewed on Mar 31, 2026

Sleep Inn Columbia
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

3 out of 5
7333 Garners Ferry Rd Columbia SC
  • 24 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Millwood Plantation Ruins and ...
7.8/10 Good! (1,001 reviews)
We enjoyed our stay.

Reviewed on Apr 3, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Wyndham Garden Columbia/Ft. Jackson

Wyndham Garden Columbia/Ft. Jackson

2.5 out of 5
1539 Horseshoe Dr Columbia SC
  • 27 min drive from Lexington Medical Center
Book a stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.8/10 Good! (1,406 reviews)
Room was newly remodeled. Very clean. The bathroom door needed to be wiped down. The breakfast was good. The coffee, Seattle’s Best, was very good. Great value!

Reviewed on Apr 3, 2026

Wyndham Garden Columbia/Ft. Jackson
Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC

2.5 out of 5
220 E Exchange Blvd Columbia SC
  • 24 min drive from Lexington Medical Center
Book a stay at this spa hotel in Columbia. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
7.8/10 Good! (1,083 reviews)
The air conditioning didn’t work, room was very dated and not very clean breakfast was ok

Reviewed on Apr 2, 2026

Country Inn & Suites by Radisson, Columbia, SC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in West Columbia

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great West Columbia hotel deals at the last minute.

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Frequently Asked Questions About West Columbia hotels

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How many hotels are there in West Columbia?

With over 1,089 hotels in West Columbia, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

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