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Santa Cruz Island Vacation Packages

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Santa Cruz Island
Galápagos
Ecuador
South America
Hotwire.com

Santa Cruz Island Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel el descanso del Guia

3.5 out of 5

Price was $636, price is now $508 per person

$508

per person

Aug 21 - Aug 25

found 18 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions Tortuga Bay Beach and Las Ninfas Lagoon are located nearby.

Todo 10/10

Reviewed on Jun 29, 2026

Galapagos Native

3 out of 5

Price was $777, price is now $532 per person

$532

per person

Aug 21 - Aug 25

found 18 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this spa guesthouse in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Tortuga Bay Beach and Fishing Piers are located nearby.

Angermeyer Waterfront Inn

3.5 out of 5

Price was $1,183, price is now $885 per person

$885

per person

Aug 22 - Aug 25

found 1 hour ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Tortuga Bay Beach and Playa de los Alemanes are located nearby.

Nicest place I’ve ever stayed. Staff greeted you with drinks, cold towel, and ac. Beautiful on water. Also next door had best pina colada I’ve ever had !

Reviewed on Jun 29, 2026

Natura Gardens Galápagos Hotel

3 out of 5

Price was $817, price is now $614 per person

$614

per person

Aug 21 - Aug 25

found 6 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this hotel in Bella Vista. Enjoy free breakfast, onsite spa services, and daily housekeeping. Popular attractions Tortuga Bay Beach and Charles Darwin Research Station are located nearby.

La Casa de Marita

3 out of 5

Price was $960, price is now $725 per person

$725

per person

Aug 22 - Aug 25

found 18 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this beach hotel in Puerto Villamil. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Concha de Perla Nature Park and Posada de Flamengos are located nearby.

The staff was very friendly and helpful. I would definitely recommend it and would return.

Reviewed on May 12, 2026

Ikala Galapagos Hotel

4 out of 5

Price was $988, price is now $761 per person

$761

per person

Aug 21 - Aug 25

found 18 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Tortuga Bay Beach and Malecon are located nearby.

Breakfast was fantastic. Staff was friendly and helpful in recommending things to do and setting up transportation for us. Beds were comfortable.

Reviewed on Jun 29, 2026

Galapagos Sea Star

2 out of 5

Save 100% on your flight

Price was $3,955, price is now $3,109 per person

$3,109

per person

Aug 21 - Aug 25

found 6 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this cruise ship in Puerto Ayora. Enjoy free breakfast, WiFi (surcharge), and daily housekeeping. Popular attractions Tortuga Bay Beach and Fishing Piers are located nearby.

Grand Hotel Leon Marino Galapagos

3 out of 5

Price was $697, price is now $553 per person

$553

per person

Aug 21 - Aug 25

found 18 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

Stay at this hotel in Puerto Ayora. Enjoy free breakfast, daily housekeeping, and laundry facilities. Popular attractions Tortuga Bay Beach and Fishing Piers are located nearby.

Las camas muy cómodas tamaño okay, buen A/C es un hotel sencillo y la ubicación excelente sino molesta la música de los restaurantes por la noche. Ya necesita mantenimiento. El Desayuno es muy limitado y sino llegas tempranito ya no alcanzas nada :( necesitan ponerle un poco de ganas y variedad porque no se antoja. Creo que sería mejor publicarlo como continental no buffet.

Reviewed on Jul 6, 2026