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South America Vacation Packages

South America Flight + Hotel packages

Melia Lima
The Westin Lima Hotel & Convention Center
Hyatt Centric San Isidro Lima
Tierra Viva Miraflores Mendiburu
Novotel Lima San Isidro Hotel
El Golf Hotel Boutique
BTH Hotel Lima Golf
Hotel Diamond Lima

3-4 Night Vacations in South America

Casa Republica Barranco Boutique Hotel
Hilton Lima Miraflores
Hotel Estelar Miraflores
Arawi Miraflores Prime

5-7 Night Vacations in South America

Melia Lima
The Westin Lima Hotel & Convention Center
Hyatt Centric San Isidro Lima
Tierra Viva Miraflores Mendiburu

Cheap Hotel Deals in South America

Rochester Classic

Rochester Classic

3.5 out of 5
Esmeralda 542, Buenos Aires, Capital Federal, 1007
The price is $72 per night from Jun 21 to Jun 22
Stay at this 3.5-star business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast, and room service. Our guests praise the breakfast and the WiFi in ...
Rochester Classic
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
25 De Mayo, 764, Buenos Aires, Capital Federal, BPN1002
The price is $123 per night from Jun 17 to Jun 18
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
Regal Pacific Buenos Aires
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65, Santiago, Region Metropolitana, 8320263
The price is $80 per night from Jun 4 to Jun 5
Stay at this 4-star business-friendly hotel in Santiago. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff in our reviews. ...
Almacruz Hotel y Centro de Convenciones

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Argentina Tango Hotel

Argentina Tango Hotel

3 out of 5
Suipacha 545, Buenos Aires, Capital Federal, C1008AAK
Stay at this 3-star business-friendly hotel in Buenos Aires. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Obelisco and Plaza ...
Argentina Tango Hotel
Mercure Santiago Centro

Mercure Santiago Centro

3.5 out of 5
Av. Libertador Bernardo O Higgins, 632, Centro, Santiago, Region Metropolitana, 8320000
The price is $67 per night from May 29 to May 30
Stay at this 3.5-star business-friendly hotel in Santiago. Enjoy free WiFi, breakfast, and room service. Our guests praise the breakfast and the helpful staff ...
Mercure Santiago Centro
Globales Republica

Globales Republica

3.5 out of 5
Cerrito 370, Buenos Aires, Capital Federal, 1010
Stay at this 3.5-star business-friendly hotel in Buenos Aires. Enjoy free WiFi, breakfast, and room service. Our guests praise the helpful staff in our reviews. ...
Globales Republica
Departamentos Amoblados Torre Tagle

Departamentos Amoblados Torre Tagle

3.5 out of 5
Monjitas 744, Santiago, Region Metropolitana, 8320000
Stay at this 3.5-star apartment in Santiago. Enjoy free WiFi, a flat-screen TV, and cable TV. Our guests praise the WiFi and the overall value in our reviews. ...
Departamentos Amoblados Torre Tagle
Hilton Buenos Aires

Hilton Buenos Aires

4.5 out of 5
Av Macacha Guemes 351, Buenos Aires, C1106BKG
The price is $215 per night from May 30 to May 31
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free WiFi, 3 bars/lounges, and 2 coffee shops/cafes. Our guests praise the breakfast and the helpful ...
Hilton Buenos Aires
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Spirit Airlines
Viva Air
KLM
American Airlines

Find cheap hotels in South America

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your South America hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in South America.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South America’s 88153 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $67. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% South America hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South America. No matter your reason for visiting South America, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South America hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South America for as low as $67.

How many hotels are there in South America?

With over 88153 hotels in South America, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $67.

How to find cheap car rentals in South America?

Finding a cheap car rental deal in is as easy as scoring cheap hotels in South America. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to South America now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to South America right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

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