Search Cheap Flights to
Santa Cruz Island

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Santa Cruz Island

Fall in love at first flight with your vacation to Santa Cruz Island by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz Island on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz Island, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz Island

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz Island with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the GPS airport.

What is the cheapest month to fly to Santa Cruz Island?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz Island are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz Island?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Santa Cruz Island.

What airport is best to fly into Santa Cruz Island?

When you’re planning your trip to Santa Cruz Island, convenience is the name of the game. Luckily, Santa Cruz Island Seymour Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz Island must-do list.

How much are flights to Santa Cruz Island?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz Island on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz Island?

The trick to saving a stack of cash on your flight to Santa Cruz Island? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Santa Cruz Island Flight Information
Destination airport
Santa Cruz Island
Destination airport IATA code
GPS

Last Minute Hotel Deals in Santa Cruz Island

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free WiFi, 3 hot tubs, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Las ...
9/10 Wonderful! (437 reviews)
"Room was clean but basic. Nice pool and breakfast"

Reviewed on Sep 15, 2026

Hotel Fiesta
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada Puerto Ayora Galapagos
Book a stay at this luxury hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a full-service spa. Popular attractions Playa de los Alemanes and Malecon ...
Finch Bay Galapagos Hotel
Maidith Galapagos Inn

Maidith Galapagos Inn

3 out of 5
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the breakfast and the helpful ...
10/10 Exceptional! (161 reviews)
"Staff are super helpful and friendly, location is good, breakfast is varied and tasty, beds are comfortable. Only downside is the lights are bright white in the rooms."

Reviewed on Sep 15, 2026

Maidith Galapagos Inn
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
Book a stay at this family-friendly hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our ...
8.8/10 Excellent! (229 reviews)
"Muy lejos del centro"

Reviewed on Sep 12, 2026

Hotel el descanso del Guia
El Barranco Galapagos

El Barranco Galapagos

2.5 out of 5
Los colonos Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and room service. Popular attractions Malecon and Gus Angermeyer Ferry Terminal are located ...
9.8/10 Exceptional! (94 reviews)
"Not a normal hotel experience. There was a dedicated house cleaner. The staff was extremely helpful. The grounds were beautiful with plenty of places to have fun hanging out around the property. It was very private but so close to the most popular tour departures. Short 3 minute walk."

Reviewed on Sep 11, 2026

El Barranco Galapagos
Hotel Cucuve

Hotel Cucuve

4 out of 5
Charles Binford 083 y Ave Charles Darwin Puerto Ayora
Stay at this B&B in Puerto Ayora. Enjoy free breakfast, free WiFi, and an airport shuttle (surcharge). Our guests praise the breakfast and the helpful staff ...
9.8/10 Exceptional! (303 reviews)
"Everything was up to expectations, great stay!"

Reviewed on Aug 29, 2026

Hotel Cucuve
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

4 out of 5
Ave. Charles Darwin S/n Y Piquero Puerto Ayora Galapagos
Book a stay at this business-friendly hotel in Puerto Ayora. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in ...
Blu Galapagos Sustainable Waterfront Lodge
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Punta Estrada Puerto Ayora Galapagos
Stay at this hotel in Puerto Ayora. Enjoy free breakfast, free WiFi, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Playa ...
9.4/10 Exceptional! (145 reviews)
"We had such an amazing stay at Hotel Angermeyer, I can't wait to go back. Everything was perfect - the staff was wonderful (thank you David and Maria for being so welcoming throughout our stay!). The restaurant was delicious with amazing sea views including sharks and seals, and we wound up eating ..."

Reviewed on Sep 14, 2026

Angermeyer Waterfront Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.