Search Deals on
Sancti Spiritus Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

Sancti Spiritus
Castile and León
Spain
Europe
Hotwire.com

Sancti Spiritus Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Senator Barajas Hotel

4 out of 5

Price was $1,419, price is now $967 per person

$967

per person

Oct 10 - Oct 16

found 17 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Madrid (MAD)

Book a stay at this business-friendly hotel in Madrid. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Bernabéu Stadium and El Retiro Park are located nearby.

Property was conveniently located to the airport and staff was very helpful and welcoming. The restaurant was delicious

Reviewed on Jul 18, 2026

Nômade Temple Madrid

5 out of 5

Save 100% on your flight

Price was $3,080, price is now $1,945 per person

$1,945

per person

Aug 23 - Aug 29

found 1 day ago

Roundtrip flight included

Boston (BOS) to Madrid (MAD)

Book a stay at this luxury hotel in Madrid. Enjoy free WiFi, an outdoor pool, and a full-service spa. Popular attractions Gran Via and Puerta del Sol are located nearby.

The place is amazing and very cozy. Great location!!

Reviewed on Jul 15, 2026

Hotel Exe Moncloa

4 out of 5

Save 100% on your flight

Price was $2,724, price is now $1,835 per person

$1,835

per person

Oct 4 - Oct 11

found 22 hours ago

Roundtrip flight included

Miami (MIA) to Madrid (MAD)

Stay at this hotel in Madrid. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Royal Palace of Madrid and Gran Via are located nearby.

The staff was delightful, very cheery and always happy to help. The rooftop bar was very relaxing, the pool a refreshing dip in the heat of the day, and breakfast was excellent. Great value for the money.. would highly recommend.

Reviewed on Jul 13, 2026

Hostal Esparteros

1 out of 5

Price was $1,983, price is now $1,359 per person

$1,359

per person

Sep 19 - Sep 25

found 19 hours ago

Roundtrip flight included

Miami (MIA) to Madrid (MAD)

Stay at this hostel in Madrid. Enjoy free WiFi, a 24-hour front desk, and housekeeping. Popular attractions Plaza Mayor and Puerta del Sol are located nearby.

Aerotel Madrid Airport - Terminal 4

3.5 out of 5

Save 100% on your flight

Price was $2,243, price is now $1,552 per person

$1,552

per person

Oct 10 - Oct 16

found 17 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Madrid (MAD)

Stay at this hotel in Madrid. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Bernabéu Stadium and Real Madrid City are located nearby.

Hostal Bernabeu

2 out of 5

Price was $1,570, price is now $1,116 per person

$1,116

per person

Oct 4 - Oct 11

found 10 hours ago

Roundtrip non-stop flight included

New York (JFK) to Madrid (MAD)

Stay at this hostal in Madrid. Enjoy free WiFi and housekeeping. Popular attractions Bernabéu Stadium and Gran Via are located nearby.

Uma Suites O'Donnell

4 out of 5

Save 100% on your flight

Price was $2,288, price is now $1,631 per person

$1,631

per person

Sep 10 - Sep 16

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Madrid (MAD)

Stay at this apartment in Madrid. Enjoy free WiFi and climate control. Popular attractions El Retiro Park and Gran Via are located nearby.

Apartment was very clean with all what we needed inside. It is also close to a lot of restaurants and the subway line as well as the Retiro park. Very great stay!

Reviewed on Jul 12, 2026

Hotel Riu Plaza España

4 out of 5

Price was $2,114, price is now $1,530 per person

$1,530

per person

Aug 23 - Aug 29

found 1 day ago

Roundtrip flight included

Boston (BOS) to Madrid (MAD)

Book a stay at this business-friendly hotel in Madrid. Enjoy free WiFi, an outdoor pool, and 2 bars/lounges. Our guests praise the breakfast and the pool in our reviews. Popular attractions Royal Palace of Madrid and Gran Via are located nearby.

Nice place to stay.Great customer service.

Reviewed on Jul 18, 2026