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Murphysboro Vacations

Pack those stellar shades. We have Murphysboro vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Murphysboro – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Murphysboro vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Murphysboro

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Murphysboro vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Murphysboro well.

Top Hotel Deals

See all 58 Hotels in Murphysboro
Americas Best Value Inn-Murphysboro/Carbondale

Americas Best Value Inn-Murphysboro/Carbondale

128 E. Walnut Street, Murphysboro
    1.5 out of 5.0
     
     

    Situated in a rural location, this motel is 1.4 mi (2.2 km) from General John A. Logan Museum and within 6 mi (10 km) of Lake Murphysboro State Park and Hickory ...

    Americas Best Value Inn-Murphysboro/Carbondale$60

    Americas Best Value Inn-Murphysboro/Carbondale$60
    Holiday Inn Carbondale-Conference Center

    Holiday Inn Carbondale-Conference Center

    2300 Reed Station Parkway, Carbondale
      3.0 out of 5.0
       
       

      Situated in Carbondale, this hotel is within 6 mi (10 km) of Railroaders Memorial, John A. Logan College, and Southern Illinois University. Hickory Ridge Public ...

      Holiday Inn Carbondale-Conference Center$118

      Holiday Inn Carbondale-Conference Center$118
      Best Western Plus Marion Hotel

      Best Western Plus Marion Hotel

      400 Comfort Dr, Marion
        2.5 out of 5.0
         
         

        Situated in Marion, this hotel is within 2 mi (3 km) of Rent One Park, Illinois Centre Mall, and Kokopelli Golf Club. Williamson County Historical Museum and ...

        Best Western Plus Marion Hotel$69

        Best Western Plus Marion Hotel$69
        Baymont Inn and Suites Marion

        Baymont Inn and Suites Marion

        2608 W Main St, Marion
          2.5 out of 5.0
           
           

          Situated in Marion, this hotel is within 2 mi (3 km) of Rent One Park, Illinois Centre Mall, and Kokopelli Golf Club. Williamson County Historical Museum and ...

          Baymont Inn and Suites Marion$72

          Baymont Inn and Suites Marion$72
          Best Western Saluki Inn

          Best Western Saluki Inn

          801 N Giant City Rd, Carbondale
            2.5 out of 5.0
             
             

            Situated in Carbondale, this hotel is 1.9 mi (3.1 km) from Railroaders Memorial and 2.9 mi (4.7 km) from Southern Illinois University. John A. Logan College ...

            Best Western Saluki Inn$110

            Best Western Saluki Inn$110
            Country Inn & Suites by Radisson, Marion, IL

            Country Inn & Suites by Radisson, Marion, IL

            1306 Halfway Road, Marion
              2.5 out of 5.0
               
               

              Situated near the airport, this hotel is within a 15-minute walk of Rent One Park and Kokopelli Golf Club. Illinois Centre Mall and Heartland Regional Medical ...

              Country Inn & Suites by Radisson, Marion, IL$80

              Country Inn & Suites by Radisson, Marion, IL$80
              Quality Inn Carbondale

              Quality Inn Carbondale

              1415 E Main St, Carbondale
                2.5 out of 5.0
                 
                 

                Located in the heart of Carbondale, this hotel is 1.9 mi (3 km) from Railroaders Memorial and 2.9 mi (4.7 km) from Southern Illinois University. John A. Logan ...

                Quality Inn Carbondale$59

                Quality Inn Carbondale$59
                Super 8 Carbondale

                Super 8 Carbondale

                1180 E Main St, Carbondale
                  2.0 out of 5.0
                   
                   

                  Situated in Carbondale, this motel is 1.2 mi (2 km) from Railroaders Memorial and 2.3 mi (3.7 km) from Southern Illinois University. Hickory Ridge Public Golf ...

                  Super 8 Carbondale$56

                  Super 8 Carbondale$56
                  Hampton Inn Marion

                  Hampton Inn Marion

                  2710 West DeYoung, Marion
                    2.5 out of 5.0
                     
                     

                    Situated in Marion, this hotel is within a 15-minute walk of Rent One Park and Illinois Centre Mall. Kokopelli Golf Club and Heartland Regional Medical Center ...

                    Hampton Inn Marion$101

                    Hampton Inn Marion$101
                    Fairfield Inn and Suites by Marriott Marion

                    Fairfield Inn and Suites by Marriott Marion

                    1400 Champion Drive, Marion
                      2.5 out of 5.0
                       
                       

                      Situated in Marion, this hotel is within 1 mi (2 km) of Rent One Park, Illinois Centre Mall, and Kokopelli Golf Club. Heartland Regional Medical Center and Williamson ...

                      Fairfield Inn and Suites by Marriott Marion$101

                      Fairfield Inn and Suites by Marriott Marion$101

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.