Search Cheap Flights to
Murphysboro

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Cheap Flights to Murphysboro

Fall in love at first flight with your vacation to Murphysboro by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Murphysboro on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Murphysboro, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Murphysboro

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Murphysboro with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MDH airport.

What is the cheapest month to fly to Murphysboro?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Murphysboro are in , but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Murphysboro?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find  to choose from for your flight to Murphysboro.

What airport is best to fly into Murphysboro?

When you’re planning your trip to Murphysboro, convenience is the name of the game. Luckily, Murphysboro Williamson County Regional Airport is nearby so you can deplane and get going on checking off everything on your Murphysboro must-do list.

How much are flights to Murphysboro?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Murphysboro on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as , you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Murphysboro?

The trick to saving a stack of cash on your flight to Murphysboro? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as  right now, why wait?

Murphysboro Flight Information
Destination airport
Murphysboro
Destination airport IATA code
MDH

Last Minute Hotel Deals in Murphysboro

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 out of 5
120 MUDDY MONSTER ROAD, Murphysboro, IL
Book a stay at this business-friendly hotel in Murphysboro. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (457 reviews)
"Hotel looked recently new. Rooms were clean and staff was really nice. Will stay there again."

Reviewed on Aug 2, 2025

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Super 8 by Wyndham Marion

Super 8 by Wyndham Marion

2 out of 5
2601 Vernell Rd, Marion, IL
Book a stay at this business-friendly motel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.6/10 Good! (1,004 reviews)
Humid basement room 101
"The room was very humid, AC did not seem to work well."

Reviewed on Aug 5, 2025

Super 8 by Wyndham Marion
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St, Marion, IL
Stay at this 3-star business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,006 reviews)
"You can’t go wron"

Reviewed on Aug 4, 2025

Drury Inn & Suites Marion
Best Western Marion Hotel

Best Western Marion Hotel

2.5 out of 5
400 Comfort Dr, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,008 reviews)
"Clean room - nice accessible shower - firm but comfortable bed - decent breakfast options."

Reviewed on Aug 5, 2025

Best Western Marion Hotel
Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

3 out of 5
2300 Reed Station Parkway, Carbondale, IL
Stay at this 3-star business-friendly hotel in Carbondale. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff in ...
8.6/10 Excellent! (585 reviews)
"Very clean room and spacious. Staff are very friendly."

Reviewed on Jul 28, 2025

Holiday Inn Carbondale-Conference Center by IHG
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 out of 5
2608 W Main St, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,034 reviews)
"Just stayed 1 night Very good 👍"

Reviewed on Jul 28, 2025

Baymont by Wyndham Marion
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

2 out of 5
1180 E Main St, Carbondale, IL
Book a stay at this business-friendly motel in Carbondale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,006 reviews)
"The staff was excellent. Very accommodating. Great price for a clean and comfortable stay. I stayed there 4 nights on a property / business trip. I was always happy returning to the room after a hard work day. Lowes is right behind the hotel. Not really close enough to walk, but the shortest drive. ..."

Reviewed on Aug 5, 2025

Super 8 by Wyndham Carbondale
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 out of 5
2609 Blue Heron Drive, Marion, IL
Book a stay at this business-friendly hotel in Marion. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (900 reviews)
"Uncomfortable beds, no bathroom fan, VERY noisy between guests above us a never ending fireworks on july 26th. Staff was wonderful. Breakfast so so."

Reviewed on Jul 27, 2025

Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.