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Mission Valley Vacation Packages

Mission Valley Flight + Hotel packages

DoubleTree by Hilton San Diego - Hotel Circle
Sheraton San Diego Hotel and Marina
Morgan Run Club & Resort
InterContinental San Diego, an IHG Hotel
Hilton San Diego Bayfront
The Sofia Hotel
The Dana on Mission Bay
Andaz San Diego - a concept by Hyatt

3-4 Night Vacations in Mission Valley

Town and Country San Diego
Sheraton San Diego Hotel and Marina
The Inn At Rancho Santa Fe, a Tribute Portfolio Hotel
InterContinental San Diego, an IHG Hotel

5-7 Night Vacations in Mission Valley

DoubleTree by Hilton San Diego - Hotel Circle
Sheraton San Diego Hotel and Marina
Andaz San Diego - a concept by Hyatt
Hilton La Jolla Torrey Pines

Cheap Hotel Deals in Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA
The price is $149 per night from Feb 5 to Feb 6
Located in Mission Valley, this spa hotel is within 3 mi (5 km) of Hotel Circle, Balboa Park, and Old Town San Diego State Park. University of San Diego and ...
Legacy Resort Hotel & Spa
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4 out of 5
7450 Hazard Center Dr, San Diego, CA
The price is $97 per night from Feb 6 to Feb 7
Located in Mission Valley, this hotel is within 1 mi (2 km) of Riverwalk Golf Club and Fashion Valley Mall. University of San Diego and Balboa Park are also ...
DoubleTree by Hilton Hotel San Diego - Mission Valley
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area

3 out of 5
4200 Taylor St, San Diego, CA
The price is $127 per night from Feb 6 to Feb 7
Located in Old Town San Diego, this hotel is within a 10-minute walk of Old Town San Diego State Park and Heritage Park. University of San Diego and SeaWorld ...
Hilton Garden Inn San Diego Old Town/SeaWorld Area

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Kings Inn San Diego - Seaworld - Zoo

Kings Inn San Diego - Seaworld - Zoo

2.5 out of 5
1333 Hotel Cir S, San Diego, CA
The price is $83 per night from Jan 30 to Jan 31
Located in Mission Valley, this hotel is within 2 mi (3 km) of Riverwalk Golf Club, Fashion Valley Mall, and Old Town San Diego State Park. University of San ...
Kings Inn San Diego - Seaworld - Zoo
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South, San Diego, CA
The price is $80 per night from Jan 30 to Jan 31
Located in Mission Valley, this hotel is within 2 mi (3 km) of Hotel Circle, Balboa Park, and Fashion Valley Mall. Old Town San Diego State Park and University ...
Best Western Seven Seas
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA
The price is $84 per night from Feb 7 to Feb 8
Located in Mission Valley, this hotel is within 2 mi (3 km) of Hotel Circle, Balboa Park, and Fashion Valley Mall. Old Town San Diego State Park and University ...
Days Inn by Wyndham San Diego Hotel Circle
Riverleaf Inn Mission Valley

Riverleaf Inn Mission Valley

2.5 out of 5
2484 Hotel Circle Place, San Diego, CA
The price is $65 per night from Feb 21 to Feb 22
Located in Mission Valley, this motel is within 2 mi (3 km) of Hotel Circle, Mission Bay, and Old Town San Diego State Park. University of San Diego and Fashion ...
Riverleaf Inn Mission Valley
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

4 out of 5
8757 Rio San Diego Dr, San Diego, CA
The price is $139 per night from Jan 30 to Jan 31
Located in Mission Valley, this hotel is 0.8 mi (1.3 km) from Mission Valley Mall and within 3 mi (5 km) of Hotel Circle and Balboa Park. Fashion Valley Mall ...
San Diego Marriott Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Find cheap hotels in Mission Valley

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mission Valley hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mission Valley.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mission Valley’s 101 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $65. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Mission Valley hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mission Valley. No matter your reason for visiting Mission Valley, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mission Valley hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mission Valley for as low as $65.

How many hotels are there in Mission Valley?

With over 101 hotels in Mission Valley, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $65.

How to find cheap car rentals in Mission Valley?

Finding a cheap car rental deal in San Diego is as easy as scoring cheap hotels in Mission Valley. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Mission Valley now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Mission Valley right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.