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Mission Valley Vacation Packages

Mission Valley Flight + Hotel packages

Fairmont Grand Del Mar
The Sofia Hotel
Kings Inn San Diego
The Westin San Diego Downtown
Carte Hotel San Diego Downtown, Curio Collection by Hilton
Kasa San Diego East Village
Best Western San Diego/Miramar Hotel
Blue Sea Beach Hotel

3-4 Night Vacations in Mission Valley

Fairmont Grand Del Mar
The Westin San Diego Downtown
The Sofia Hotel
Rancho Bernardo Inn

5-7 Night Vacations in Mission Valley

The Sofia Hotel
Kings Inn San Diego
InterContinental San Diego, an IHG Hotel
The Atwood

Cheap Hotel Deals in Mission Valley

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

3 out of 5
543 Hotel Circle S, San Diego, CA, 92108
The price is $101 per night from May 30 to May 31
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the helpful staff and the ...
Days Inn by Wyndham San Diego Hotel Circle
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South, San Diego, CA, 92108
The price is $179 per night from Jun 26 to Jun 27
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, a full-service spa, and breakfast. Our guests praise the helpful staff and the clean rooms in our ...
Legacy Resort Hotel & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South, San Diego, CA, 92108
The price is $103 per night from May 30 to May 31
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 spa tubs. Our guests praise the restaurant and the helpful staff ...
Best Western Seven Seas

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Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA, 92108
The price is $129 per night from May 31 to Jun 1
Stay at this 3.5-star golf hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. Popular ...
Handlery Hotel
Kings Inn San Diego

Kings Inn San Diego

2.5 out of 5
1333 Hotel Cir S, San Diego, CA, 92108
The price is $119 per night from May 30 to May 31
Stay at this hotel in San Diego. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the breakfast and the restaurant in our reviews. Popular ...
Kings Inn San Diego
DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle

4 out of 5
1515 Hotel Cir S, San Diego, CA, 92108
The price is $150 per night from May 30 to May 31
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
DoubleTree by Hilton San Diego - Hotel Circle
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA, 92108
The price is $156 per night from May 30 to May 31
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 24-hour room service, and a 24-hour fitness center. Our guests praise the bar and ...
Hilton San Diego Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA, 92108
The price is $125 per night from Jun 6 to Jun 7
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast, and 24-hour room service. Our guests praise the helpful staff and the clean ...
Sheraton Mission Valley San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Find cheap hotels in Mission Valley

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Mission Valley hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Mission Valley.

Choosing the right hotel in California has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Mission Valley’s 101 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $101. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Mission Valley hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Mission Valley. No matter your reason for visiting Mission Valley, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Mission Valley hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Mission Valley for as low as $101.

How many hotels are there in Mission Valley?

With over 101 hotels in Mission Valley, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $101.

How to find cheap car rentals in Mission Valley?

Finding a cheap car rental deal in San Diego is as easy as scoring cheap hotels in Mission Valley. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Mission Valley now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Mission Valley right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.