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Hotels in Lancaster

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Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
  • 7 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,357 reviews)
"It was very clean and all required furniture and device"

Reviewed on Nov 9, 2026

Buffalo Airport Hotel
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road Grand Island NY
  • 38 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (2,234 reviews)
"Decent place, felt outdated though."

Reviewed on Nov 9, 2026

Holiday Inn Express Grand Island - Niagara Falls by IHG
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
  • 7 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (3,348 reviews)
"The only plus to the entire hotel was the bed was comfortable. The bathroom was so dated and the sink was cracked and old. the shower was decrepit and old. The water pressure was non existent. We did not eat the breakfast after taking a look at it. Eggs looked powdered not real eggs. I will not go ..."

Reviewed on Nov 9, 2026

M Hotel Buffalo
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
  • 8 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff and ...
7.4/10 Good! (2,730 reviews)
"Our room was clean but no microwave and the common one was not working. Ice machine was not working on our floor, sauna that they show on their website was not working, We had a women who was staying there ask us if the carpet in our room was dirty because hers was but fortunately we had wood floors ..."

Reviewed on Nov 9, 2026

Garden Place Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
  • 7 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Sleep Inn & Suites Buffalo Airport
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
  • 15 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, a free area shuttle, and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,900 reviews)
"Nice"

Reviewed on Nov 9, 2026

Wyndham Garden Buffalo Downtown
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
  • 16 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,847 reviews)
"Clean and safe space"

Reviewed on Nov 9, 2026

Hyatt Regency Buffalo / Hotel and Conference Center
Comfort Inn & Suites Niagara Falls Blvd USA

Comfort Inn & Suites Niagara Falls Blvd USA

2.5 out of 5
6115 Niagara Falls Blvd Niagara Falls NY
  • 43 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Niagara Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Comfort Inn & Suites Niagara Falls Blvd USA
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

3 out of 5
6619 Transit Rd Buffalo NY
  • 8 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
La Quinta Inn by Wyndham Buffalo Airport
Best Western Buffalo Inn & Suites

Best Western Buffalo Inn & Suites

2.5 out of 5
50 Freeman Rd Buffalo NY
  • 9 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Best Western Buffalo Inn & Suites
Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

3 out of 5
4345 Genesee St Buffalo NY
  • 7 min drive from Lancaster Opera House
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Comfort Inn & Suites Buffalo Airport
Fairbridge Inn Express Buffalo Airport Williamsville

Fairbridge Inn Express Buffalo Airport Williamsville

2 out of 5
7200 Transit Road Buffalo NY
  • 11 min drive from Lancaster Opera House
Stay at this hotel in Buffalo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Walden Galleria Mall and Samuel’s Grande Manor are ...
4.8/10 (1,178 reviews)
"Horrible experience. The room was so disgusting we had to leave in the middle of the night and go find somewhere else to sleep. Stains on the bed, pillows, walls, ceiling, toilet and all over bathroom, curtains, and floor. Lamps and TV didn’t work. The room smelled worse than a hockey locker room. ..."

Reviewed on Nov 9, 2026

Fairbridge Inn Express Buffalo Airport Williamsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Lancaster

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $69. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Lancaster hotel deals at the last minute.

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Frequently Asked Questions About Lancaster hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Lancaster?

With over 880 hotels in Lancaster, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $69.

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Finding a cheap car rental deal in Lancaster is as easy as scoring cheap hotels in Lancaster. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.