Search Deals on
Isla Santay Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

Isla Santay
Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Isla Santay Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Chat Noir Cuenca

3 out of 5

Price was $276, price is now $197 per person

$197

per person

Dec 24 - Dec 27

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hotel in Cuenca. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions Cúpulas Lookout and Calderon Park are located nearby.

Hotel El Conquistador

4 out of 5

Price was $394, price is now $214 per person

$214

per person

Dec 24 - Dec 27

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Plaza Rotary Market and Calderon Park are located nearby.

Toallas viejas y manchadas

Reviewed on Sep 18, 2026

Mansión Alcázar Boutique Hotel

4 out of 5

Price was $641, price is now $377 per person

$377

per person

Dec 12 - Dec 18

found 2 hours ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Excellent stay. Beautiful and great service 100/10

Reviewed on Nov 4, 2026

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Price was $2,332, price is now $1,408 per person

$1,408

per person

Dec 6 - Dec 11

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5

Price was $525, price is now $385 per person

$385

per person

Dec 24 - Dec 27

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this luxury hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

El calor en mi habitación era fuerte La calidad del papel higiénico y de los artículos de tocador tienen mucha oportunidad de mejora El desayuno un 7/10 Creo que estos puntos mencionados hacen que la relación precio calidad no sea la apropiada Por lo demás muy bien!

Reviewed on Nov 4, 2026

Hospedaje Casa Aida Victoria

1 out of 5

Price was $18,888, price is now $14,284 per person

$14,284

per person

Dec 24 - Dec 27

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Stay at this hostel in Cuenca. Enjoy free WiFi. Popular attractions Cúpulas Lookout and Convent of the Assumption are located nearby.

Hotel Boutique Santa Lucia

4 out of 5

Price was $1,309, price is now $1,001 per person

$1,001

per person

Jan 22 - Jan 29

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Guayaquil (GYE)

Book a stay at this boutique hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Calderon Park and Cúpulas Lookout are located nearby.

Great place

Reviewed on Oct 28, 2026

Eolia Sustainable Design Hotel

4 out of 5

Price was $1,194, price is now $920 per person

$920

per person

Dec 14 - Dec 18

found 6 hours ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)

Book a stay at this beach hotel in Manta. Enjoy free breakfast, free WiFi, and a private beach. Popular attractions Playa Santa Marianita and Umiña Tennis Club are located nearby.

Un hotei muy bonito con muy mal servicio

Reviewed on Nov 2, 2026