Search Deals on
Isla Santay Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

Isla Santay
Guayaquil
Guayas
Ecuador
South America
Hotwire.com

Isla Santay Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Santa Lucia Suites - Barranco

3.5 out of 5

Price was $258, price is now $187 per person

$187

per person

Dec 4 - Dec 7

found 23 hours ago

Roundtrip flight included

Guayaquil (GYE) to Guayaquil (GYE)

Stay at this aparthotel in Cuenca. Enjoy free WiFi, in-room massages, and an airport shuttle (surcharge). Popular attractions Inter-American Center of Popular Arts and Río Tomebamba & Calle Larga are located nearby.

Balcony great. Bathroom needs cleaning and update.

Reviewed on Oct 16, 2026

Hotel El Conquistador

4 out of 5

Price was $365, price is now $200 per person

$200

per person

Dec 4 - Dec 7

found 23 hours ago

Roundtrip flight included

Guayaquil (GYE) to Guayaquil (GYE)

Book a stay at this business-friendly hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions Plaza Rotary Market and Calderon Park are located nearby.

Toallas viejas y manchadas

Reviewed on Sep 18, 2026

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5

Price was $2,431, price is now $1,481 per person

$1,481

per person

Dec 6 - Dec 11

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)

Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.

Hotel Boutique Santa Lucia

4 out of 5

Price was $411, price is now $263 per person

$263

per person

Dec 4 - Dec 7

found 23 hours ago

Roundtrip flight included

Guayaquil (GYE) to Guayaquil (GYE)

Book a stay at this boutique hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Calderon Park and Cúpulas Lookout are located nearby.

Great place

Reviewed on Oct 28, 2026

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5

Price was $546, price is now $386 per person

$386

per person

Dec 4 - Dec 7

found 23 hours ago

Roundtrip flight included

Guayaquil (GYE) to Guayaquil (GYE)

Book a stay at this luxury hotel in Cuenca. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Our room was unbearably hot. Imposible to sleep. Front desk’s response was that the city was unusually warm. Restaurant was very uneven, could be rated a 1 or a 5 depending on the day or meal.

Reviewed on Oct 24, 2026

Mansión Alcázar Boutique Hotel

4 out of 5

Price was $733, price is now $537 per person

$537

per person

Dec 5 - Dec 9

found 1 day ago

Roundtrip flight included

Quito (UIO) to Guayaquil (GYE)

Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Sebastian Plaza and Museum of Modern Art are located nearby.

Hospedaje Casa Aida Victoria

1 out of 5

Price was $44,766, price is now $32,954 per person

$32,954

per person

Jan 22 - Jan 29

found 1 day ago

Roundtrip non-stop flight included

New York (JFK) to Guayaquil (GYE)

Stay at this hostel in Cuenca. Enjoy free WiFi. Popular attractions Cúpulas Lookout and Convent of the Assumption are located nearby.

Oro Verde Cuenca

4.5 out of 5

Price was $348, price is now $267 per person

$267

per person

Dec 4 - Dec 7

found 23 hours ago

Roundtrip flight included

Guayaquil (GYE) to Guayaquil (GYE)

Book a stay at this luxury hotel in Cuenca. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions Museum of Modern Art and San Sebastian Plaza are located nearby.

Great place to stay and enjoy the city!

Reviewed on Oct 23, 2026