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Isla Santay Vacation Packages

Build your package with 2 more options

Isla Santay Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Oro Verde Machala

Oro Verde Machala

4 out of 5
Price was $336, price is now $280 per person
$280
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
Book a stay at this business-friendly hotel in Machala. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Unioro Shopping Center and Centro de Arte y Cultura "Luz Victoria Rivera de Mora" are located nearby.
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Reviewed on Aug 22, 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5
Save 100% on your flight
Price was $1,842, price is now $1,254 per person
$1,254
per person
Oct 23 - Oct 27
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and onsite spa services. Popular attractions Numa Pompilio Llona Street and Santa Ana Hill are located nearby.
The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.

Reviewed on Oct 25, 2025

Hotel del Parque

Hotel del Parque

4.5 out of 5
Price was $1,632, price is now $1,214 per person
$1,214
per person
Oct 24 - Oct 29
found 22 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Book a stay at this luxury hotel in Samborondon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Histórico Guayaquil and Guayaquil Historic Park are located nearby.
Tuvimos problemas con el internet se demoraron en solucionarlo pero cuando lo solucionaron quedo bien El restaurante del desayuno hacia demasiado calor Entiendo q es al aire libre pero que valor Tuve q volver a bañarme

Reviewed on Aug 17, 2026

Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel

4 out of 5
Price was $992, price is now $763 per person
$763
per person
Oct 14 - Oct 18
found 11 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Book a stay at this spa hotel in Cuenca. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions San Francisco Plaza Market and San Sebastian Plaza are located nearby.
El hotel muy lindo y su encanto especial, lo único un poco incomodo la cama muy pequena

Reviewed on Aug 4, 2026

Hotel Ramada

Hotel Ramada

3 out of 5
Price was $759, price is now $617 per person
$617
per person
Oct 23 - Oct 27
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
Stay at this hotel in Guayaquil. Enjoy free breakfast, free WiFi, and room service. Popular attractions Chocolate Museum and Museum of Anthropology and Contemporary Art are located nearby.

Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

4 out of 5
Price was $906, price is now $739 per person
$739
per person
Oct 14 - Oct 18
found 11 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Book a stay at this boutique hotel in Cuenca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Calderon Park and Convent of the Assumption are located nearby.
El hotel es muy lindo, colonial pero con todas las comodidades. La ubicación excelente 👌

Reviewed on Aug 21, 2026

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Price was $686, price is now $577 per person
$577
per person
Oct 23 - Oct 27
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
Stay at this aparthotel in Guayaquil. Enjoy free WiFi, a fitness center, and parking (surcharge). Popular attractions Santa Ana Hill and Botanical Garden are located nearby.

Hotel Boutique Los Balcones

Hotel Boutique Los Balcones

3.5 out of 5
Price was $348, price is now $293 per person
$293
per person
Sep 24 - Sep 27
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
Book a stay at this family-friendly hotel in Cuenca. Enjoy free breakfast, a rooftop terrace, and room service. Popular attractions Civic Plaza and Plaza Rotary Market are located nearby.

Isla Santay Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel Ramada

Hotel Ramada

3 out of 5
Downtown Guayaquil
Price was $759, price is now $617 per person
$617
per person
Oct 23 - Oct 27
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5
Tarqui
Save 100% on your flight
Price was $1,842, price is now $1,254 per person
$1,254
per person
Oct 23 - Oct 27
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
Mansión Alcázar Boutique Hotel

Mansión Alcázar Boutique Hotel

4 out of 5
Downtown Cuenca
Price was $992, price is now $763 per person
$763
per person
Oct 14 - Oct 18
found 11 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

4 out of 5
Downtown Cuenca
Price was $906, price is now $739 per person
$739
per person
Oct 14 - Oct 18
found 11 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)

Isla Santay Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana
Price was $858, price is now $710 per person
$710
per person
Oct 24 - Oct 29
found 22 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Hotel del Parque

Hotel del Parque

4.5 out of 5
Price was $1,760, price is now $1,210 per person
$1,210
per person
Oct 4 - Oct 9
found 3 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5
Tarqui
Save 100% on your flight
Price was $2,241, price is now $1,610 per person
$1,610
per person
Oct 24 - Oct 29
found 22 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)
Hotel Marcelius

Hotel Marcelius

3.5 out of 5
Kennedy
Price was $851, price is now $733 per person
$733
per person
Oct 24 - Oct 29
found 22 hours ago
Roundtrip flight included
New York (NYC) to Guayaquil (GYE)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

LATAM Airlines Group
Wed, Aug 26 - Sun, Aug 30
UIO
Mariscal Sucre Intl.
GYE
Jose Joaquin de Olmedo Intl.
$180 Roundtrip, found 1 day ago
$180
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Wed, Aug 26 from Mariscal Sucre Intl. to Jose Joaquin de Olmedo Intl., returning Sun, Aug 30, priced at $180 found 1 day ago
Arajet
Mon, Jan 18 - Sat, Jan 23
MIA
Miami Intl.
GYE
Jose Joaquin de Olmedo Intl.
$323 Roundtrip, found 1 day ago
$323
Roundtrip
found 1 day ago
Select Arajet flight, departing Mon, Jan 18 from Miami Intl. to Jose Joaquin de Olmedo Intl., returning Sat, Jan 23, priced at $323 found 1 day ago
Copa
Fri, Oct 23 - Fri, Nov 6
MCO
Orlando Intl.
GYE
Jose Joaquin de Olmedo Intl.
$416 Roundtrip, found 1 day ago
$416
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 23 from Orlando Intl. to Jose Joaquin de Olmedo Intl., returning Fri, Nov 6, priced at $416 found 1 day ago
American Airlines
Mon, Oct 26 - Tue, Nov 3
JFK
John F. Kennedy Intl.
GYE
Jose Joaquin de Olmedo Intl.
$456 Roundtrip, found 1 day ago
$456
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Oct 26 from John F. Kennedy Intl. to Jose Joaquin de Olmedo Intl., returning Tue, Nov 3, priced at $456 found 1 day ago