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Hartsville Vacations

Pack those stellar shades. We have Hartsville vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Hartsville – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Hartsville vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Hartsville

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Hartsville vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Hartsville well.

Top Hotel Deals

See all 57 Hotels in Hartsville
The Landmark Inn

The Landmark Inn

1301 South 4th Street, Hartsville
    2.5 out of 5.0
     
     

    Situated in Hartsville, this motel is 1.7 mi (2.7 km) from Hartsville Museum and 1.7 mi (2.8 km) from Coker College. Segars-McKinnon Heritage Preserve and Darlington ...

    Fairfield Inn by Marriott Hartsville

    Fairfield Inn by Marriott Hartsville

    200 S 4th St, Hartsville
      2.5 out of 5.0
       
       

      Situated in Hartsville, this hotel is within a 5-minute walk of Coker College and Hartsville Museum. Segars-McKinnon Heritage Preserve is 2.8 mi (4.5 km) ...

      Fairfield Inn by Marriott Hartsville$99

      Fairfield Inn by Marriott Hartsville$99
      Hampton Inn & Suites Hartsville

      Hampton Inn & Suites Hartsville

      203 East Carolina Ave., Hartsville
        2.5 out of 5.0
         
         

        Located in the heart of Hartsville, this hotel is within a 5-minute walk of Coker College and Hartsville Museum. Segars-McKinnon Heritage Preserve is 2.8 mi ...

        Hampton Inn & Suites Hartsville$109

        Hampton Inn & Suites Hartsville$109
        Quality Inn

        Quality Inn

        903 S 5th Street, Hartsville
          2.5 out of 5.0
           
           

          Situated in Hartsville, this hotel is 1.2 mi (2 km) from Hartsville Museum and 1.5 mi (2.4 km) from Coker College. Segars-McKinnon Heritage Preserve and Darlington ...

          Quality Inn$75

          Quality Inn$75
          Oak Manor Inn

          Oak Manor Inn

          314 EAST HOME AVE, Hartsville
            3.0 out of 5.0
             
             

            Situated in Hartsville, this bed & breakfast is within a 10-minute walk of Coker College and Hartsville Museum. Segars-McKinnon Heritage Preserve is 2.9 mi (4.6 ...

            Baymont Inn & Suites Florence by Wyndham

            Baymont Inn & Suites Florence by Wyndham

            1826 W Lucas Street, Florence
              2.0 out of 5.0
               
               

              Situated in Florence, this hotel is within 6 mi (10 km) of Mcleod Regional Medical Center, Florence Museum, and Florence Civic Center. Magnolia Mall and Darlington ...

              Baymont Inn & Suites Florence by Wyndham$52

              Baymont Inn & Suites Florence by Wyndham$52
              Red Roof Inn Florence - Civic Center

              Red Roof Inn Florence - Civic Center

              2690 David H McLeod Boulevard, Florence
                2.0 out of 5.0
                 
                 

                Situated near the airport, this hotel is within a 10-minute walk of Magnolia Mall and Florence Civic Center. Florence Museum and Mcleod Regional Medical Center ...

                Red Roof Inn Florence - Civic Center$58

                Red Roof Inn Florence - Civic Center$58
                Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327

                Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327

                2101 Florence Harllee Blvd, Florence
                  2.5 out of 5.0
                   
                   

                  Situated in Florence, this hotel is within 9 mi (15 km) of Francis Marion University, Eastern Carolina Agricultural Fairgrounds, and Florence Museum. Mcleod ...

                  Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327$119

                  Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327$119
                  Ramada by Wyndham Florence Center

                  Ramada by Wyndham Florence Center

                  1819 West Lucas Street, Florence
                     
                     

                    Situated in Florence, this hotel is within 6 mi (10 km) of Florence Museum, Mcleod Regional Medical Center, and Florence Civic Center. Magnolia Mall and Darlington ...

                    Ramada by Wyndham Florence Center$67

                    Ramada by Wyndham Florence Center$67
                    Quality Inn And Suites Civic

                    Quality Inn And Suites Civic

                    150 Dunbarton Dr, Florence
                      2.5 out of 5.0
                       
                       

                      Located in the heart of Florence, this hotel is within a 15-minute walk of Magnolia Mall and Florence Civic Center. Florence Museum and Mcleod Regional Medical ...

                      Quality Inn And Suites Civic$100

                      Quality Inn And Suites Civic$100

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.