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Santa Cruz

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Santa Cruz Flights as Low as $286

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$286 Roundtrip, found 6 hours ago
$286
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $286 found 6 hours ago
Copa
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$322 Roundtrip, found 6 hours ago
$322
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $322 found 6 hours ago
Copa
Sat, Oct 4 - Fri, Oct 17
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$334 Roundtrip, found 6 hours ago
$334
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Fri, Oct 17, priced at $334 found 6 hours ago
Copa
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$359 Roundtrip, found 6 hours ago
$359
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $359 found 6 hours ago
Copa
Sun, Oct 5 - Fri, Oct 17
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$371 Roundtrip, found 6 hours ago
$371
Roundtrip
found 6 hours ago
Select Copa flight, departing Sun, Oct 5 from Miami Intl. to Enrique Malek Intl., returning Fri, Oct 17, priced at $371 found 6 hours ago
Copa
Wed, Oct 8 - Sat, Oct 11
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$381 Roundtrip, found 3 days ago
$381
Roundtrip
found 3 days ago
Select Copa flight, departing Wed, Oct 8 from Miami Intl. to Enrique Malek Intl., returning Sat, Oct 11, priced at $381 found 3 days ago
Copa
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$386 Roundtrip, found 6 hours ago
$386
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $386 found 6 hours ago
Copa
Fri, Oct 10 - Sat, Oct 11
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$396 Roundtrip, found 6 hours ago
$396
Roundtrip
found 6 hours ago
Select Copa flight, departing Fri, Oct 10 from Miami Intl. to Enrique Malek Intl., returning Sat, Oct 11, priced at $396 found 6 hours ago
Copa
Sat, Oct 4 - Sun, Oct 19
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$399 Roundtrip, found 6 hours ago
$399
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Sun, Oct 19, priced at $399 found 6 hours ago
Copa
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$407 Roundtrip, found 6 hours ago
$407
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $407 found 6 hours ago
Copa
Sat, Oct 4 - Thu, Oct 16
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$409 Roundtrip, found 6 hours ago
$409
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Thu, Oct 16, priced at $409 found 6 hours ago
Copa
Wed, Jul 9 - Wed, Jul 23
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$417 Roundtrip, found 7 hours ago
$417
Roundtrip
found 7 hours ago
Select Copa flight, departing Wed, Jul 9 from Miami Intl. to Enrique Malek Intl., returning Wed, Jul 23, priced at $417 found 7 hours ago
Copa
Fri, Nov 28 - Thu, Dec 11
RDU
Raleigh - Durham Intl.
DAV
Enrique Malek Intl.
$587 Roundtrip, found 3 days ago
$587
Roundtrip
found 3 days ago
Select Copa flight, departing Fri, Nov 28 from Raleigh - Durham Intl. to Enrique Malek Intl., returning Thu, Dec 11, priced at $587 found 3 days ago
United
Sat, Oct 4 - Mon, Oct 13
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$695 Roundtrip, found 6 hours ago
$695
Roundtrip
found 6 hours ago
Select United flight, departing Sat, Oct 4 from Miami Intl. to Enrique Malek Intl., returning Mon, Oct 13, priced at $695 found 6 hours ago
Copa
Sat, Jul 12 - Mon, Jul 21
IAD
Washington Dulles Intl.
DAV
Enrique Malek Intl.
$763 Roundtrip, found 6 hours ago
$763
Roundtrip
found 6 hours ago
Select Copa flight, departing Sat, Jul 12 from Washington Dulles Intl. to Enrique Malek Intl., returning Mon, Jul 21, priced at $763 found 6 hours ago
United
Mon, Sep 15 - Sun, Sep 21
SHV
Shreveport Regional
DAV
Enrique Malek Intl.
$936 Roundtrip, found 1 day ago
$936
Roundtrip
found 1 day ago
Select United flight, departing Mon, Sep 15 from Shreveport Regional to Enrique Malek Intl., returning Sun, Sep 21, priced at $936 found 1 day ago

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DAV airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in October, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Enrique Malek Intl. Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $286, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $286 right now, why wait?

Santa Cruz Flight Information
Destination airport
Enrique Malek Intl.
Destination airport IATA code
DAV
Roundtrip price
$285

Last Minute Hotel Deals in Santa Cruz

Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
3 out of 5
Volcan, Via Cerro Punta, Volcan, Chiriqui
Stay at this 3-star family-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida ...
8/10 Very Good! (220 reviews)
Una noche en Bambito
"Escoger el Hotel Bambito para nuestra estadía en Volcán fue lo mejor. Un hotel con una hermosa infraestructura, sus jardines espectaculares, su piscina y jacuzzi. Todo su personal de lo más amable y siempre dispuestos a ayudar, en especial el sr. Melvin quien nos atendió en el bar y nos regaló una ..."

Reviewed on Mar 28, 2025

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Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Hotel Dos Rios
Hotel Dos Rios
3 out of 5
43, Nueva California, Nueva California
Stay at this 3-star hotel in Nueva California. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida Lagunas ...
8.4/10 Very Good! (68 reviews)
"The landscaping is beautiful and the food was excellent. Great strawberry margaritas too. Saff friendly and helpful. Very cool.setting."

Reviewed on May 4, 2025

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Hotel Dos Rios
Casa Grande Bambito Resort
Casa Grande Bambito Resort
4 out of 5
Calle El Manantial, Paso Ancho, Chiriqui
Stay at this 4-star family-friendly hotel in Paso Ancho. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Barriles and Área Silvestre ...
"We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ..."

Reviewed on Jan 15, 2025

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Casa Grande Bambito Resort
Linda Vista Cabins
Linda Vista Cabins
3 out of 5
Calle 35 sur oeste, Urb. Linda Vista, Alto Boquete, Chiriqui
Stay at this 3-star cabin in Alto Boquete. Enjoy free WiFi, free parking, and a garden. Popular attractions Schumann's Park and Boquete Library are located ...
9/10 Wonderful! (17 reviews)
"Excellent accueil, maison très agréable, parfait pour relaxer, vue magnifique, proche de tout en voiture, e cellente adresse"

Reviewed on Mar 15, 2025

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Linda Vista Cabins
Los Quetzales Ecolodge & Spa
Los Quetzales Ecolodge & Spa
3 out of 5
Guadalupe, Cerro Punta, Chiriqui
Stay at this 3-star spa lodge in Cerro Punta. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Finca Dracula Orchid Sanctuary and The ...
8.6/10 Excellent! (28 reviews)
Relajante en todos los sentidos.
"Los quetzales siempre será muy recomendado de mi parte, sobre todo para las personas que buscan desconectarse de todo el bullicio y estrés de la ciudad. El clima lo máximo, el servicio del personal excelente, la habitación cómoda, la verdad 1000% recomendados."

Reviewed on Mar 5, 2025

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Los Quetzales Ecolodge & Spa
Hotel Finca Lerida
Hotel Finca Lerida
3 out of 5
Alto Quiel, Los Naranjos, Chiriqui
Stay at this 3-star hotel in Los Naranjos. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Finca Lérida Coffee Estate and Los Ladrillos ...
8.6/10 Excellent! (178 reviews)
"Nice amenities and staff, however is expensive for academic groups. The should offer better deals."

Reviewed on Jun 9, 2025

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Hotel Finca Lerida
Luxury Canyon Suites
Luxury Canyon Suites
2 out of 5
La Tranca, Alto Boquete, Provincia de Chiriquí
Stay at this hotel in Alto Boquete. Enjoy free WiFi, daily housekeeping, and meeting facilities. Popular attractions Boquete Community Market and Schumann's ...
7/10 Good! (2 reviews)
"New place, still developing"

Reviewed on Mar 4, 2025

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Luxury Canyon Suites
Los Brezos Boutique Hotel
Los Brezos Boutique Hotel
3.5 out of 5
Calle Tercera Norte, Volcan, Chiriquí
Stay at this 3.5-star business-friendly hotel in Volcan. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Barriles and Área Silvestre Protegida ...
9.4/10 Exceptional! (21 reviews)
"Hotel was extremely clean and attractive, with a nice restaurant. The only downside was construction across the street, which made it somewhat noisy, although it will stop as soon as the building is finished."

Reviewed on Feb 22, 2025

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Los Brezos Boutique Hotel
See all 43 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.