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Santa Cruz Vacation Packages

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Santa Cruz
Chiriquí Province
Panama
Mexico and Central America
Hotwire.com

Santa Cruz Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,475, price is now $969 per person

$969

per person

Aug 7 - Aug 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $2,159, price is now $1,132 per person

$1,132

per person

Aug 7 - Aug 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Save 100% on your flight

Price was $1,796, price is now $1,181 per person

$1,181

per person

Aug 7 - Aug 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Casa Mallet by Wynwood House

4 out of 5

Price was $1,644, price is now $1,162 per person

$1,162

per person

Jul 8 - Jul 12

found 18 hours ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Las Clementinas

3.5 out of 5

Price was $1,574, price is now $1,126 per person

$1,126

per person

Aug 10 - Aug 16

found 1 day ago

Roundtrip flight included

Nassau (NAS) to Panama City (PTY)

Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Sofitel Legend Casco Viejo, Panama City

5 out of 5

Save 100% on your flight

Price was $2,496, price is now $1,789 per person

$1,789

per person

Aug 7 - Aug 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Boutique Apartments Panamá Coco del Mar

3.5 out of 5

Save 100% on your flight

Price was $5,045, price is now $3,652 per person

$3,652

per person

Jul 20 - Jul 27

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.

Hyatt Regency Panama City

5 out of 5

Price was $1,606, price is now $1,167 per person

$1,167

per person

Aug 7 - Aug 14

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.