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Carlisle

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Carlisle Flights as Low as $192

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Mon, May 25 - Mon, Jun 1
DEN
Denver Intl.
DSM
Des Moines Intl.
$192 Roundtrip, found 5 hours ago
$192
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Mon, May 25 from Denver Intl. to Des Moines Intl., returning Mon, Jun 1, priced at $192 found 5 hours ago
Bargain Flight
Fri, Apr 3 - Mon, Apr 20
DTW
Detroit Metropolitan Wayne County
DSM
Des Moines Intl.
$212 Roundtrip, found 1 day ago
$212
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Fri, Apr 3 from Detroit Metropolitan Wayne County to Des Moines Intl., returning Mon, Apr 20, priced at $212 found 1 day ago
Frontier Airlines
Fri, Apr 3 - Mon, Apr 20
AUS
Austin-Bergstrom Intl.
DSM
Des Moines Intl.
$221 Roundtrip, found 9 hours ago
$221
Roundtrip
found 9 hours ago
Select Frontier Airlines flight, departing Fri, Apr 3 from Austin-Bergstrom Intl. to Des Moines Intl., returning Mon, Apr 20, priced at $221 found 9 hours ago
Frontier Airlines
Fri, Apr 17 - Mon, Apr 20
DFW
Dallas-Fort Worth Intl.
DSM
Des Moines Intl.
$232 Roundtrip, found 13 hours ago
$232
Roundtrip
found 13 hours ago
Select Frontier Airlines flight, departing Fri, Apr 17 from Dallas-Fort Worth Intl. to Des Moines Intl., returning Mon, Apr 20, priced at $232 found 13 hours ago
Frontier Airlines
Fri, Apr 17 - Mon, Apr 20
IAH
George Bush Intercontinental
DSM
Des Moines Intl.
$232 Roundtrip, found 1 day ago
$232
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Apr 17 from George Bush Intercontinental to Des Moines Intl., returning Mon, Apr 20, priced at $232 found 1 day ago
Frontier Airlines
Tue, Mar 17 - Fri, Mar 20
MCO
Orlando Intl.
DSM
Des Moines Intl.
$240 Roundtrip, found 3 days ago
$240
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Tue, Mar 17 from Orlando Intl. to Des Moines Intl., returning Fri, Mar 20, priced at $240 found 3 days ago
Frontier Airlines
Fri, Apr 3 - Mon, Apr 13
PHX
Sky Harbor Intl.
DSM
Des Moines Intl.
$253 Roundtrip, found 5 days ago
$253
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Fri, Apr 3 from Sky Harbor Intl. to Des Moines Intl., returning Mon, Apr 13, priced at $253 found 5 days ago
Bargain Flight
Wed, May 27 - Sat, May 30
CLT
Charlotte-Douglas Intl.
DSM
Des Moines Intl.
$256 Roundtrip, found 1 day ago
$256
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Wed, May 27 from Charlotte-Douglas Intl. to Des Moines Intl., returning Sat, May 30, priced at $256 found 1 day ago
Bargain Flight
Tue, Mar 31 - Tue, Apr 7
MEM
Memphis Intl.
DSM
Des Moines Intl.
$256 Roundtrip, found 1 day ago
$256
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Tue, Mar 31 from Memphis Intl. to Des Moines Intl., returning Tue, Apr 7, priced at $256 found 1 day ago
Frontier Airlines
Wed, Mar 25 - Mon, Apr 6
LAX
Los Angeles Intl.
DSM
Des Moines Intl.
$260 Roundtrip, found 3 hours ago
$260
Roundtrip
found 3 hours ago
Select Frontier Airlines flight, departing Wed, Mar 25 from Los Angeles Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $260 found 3 hours ago
Bargain Flight
Sat, May 2 - Sat, May 9
CLD
McClellan-Palomar
DSM
Des Moines Intl.
$290 Roundtrip, found 4 days ago
$290
Roundtrip
found 4 days ago
Select Bargain Flight flight, departing Sat, May 2 from McClellan-Palomar to Des Moines Intl., returning Sat, May 9, priced at $290 found 4 days ago
American Airlines
Tue, Jul 28 - Sat, Aug 8
EWR
Newark Liberty Intl. Airport
DSM
Des Moines Intl.
$327 Roundtrip, found 14 hours ago
$327
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Tue, Jul 28 from Newark Liberty Intl. Airport to Des Moines Intl., returning Sat, Aug 8, priced at $327 found 14 hours ago
United
Wed, Jun 24 - Tue, Jul 7
GUC
Gunnison-Crested Butte Regional
DSM
Des Moines Intl.
$361 Roundtrip, found 19 hours ago
$361
Roundtrip
found 19 hours ago
Select United flight, departing Wed, Jun 24 from Gunnison-Crested Butte Regional to Des Moines Intl., returning Tue, Jul 7, priced at $361 found 19 hours ago
Bargain Flight
Sat, Aug 15 - Tue, Aug 18
BWI
Baltimore Washington Intl. Thurgood Marshall
DSM
Des Moines Intl.
$366 Roundtrip, found 20 hours ago
$366
Roundtrip
found 20 hours ago
Select Bargain Flight flight, departing Sat, Aug 15 from Baltimore Washington Intl. Thurgood Marshall to Des Moines Intl., returning Tue, Aug 18, priced at $366 found 20 hours ago
Bargain Flight
Thu, Apr 2 - Mon, Apr 6
ATL
Hartsfield-Jackson Atlanta Intl.
DSM
Des Moines Intl.
$395 Roundtrip, found 1 day ago
$395
Roundtrip
found 1 day ago
Select Bargain Flight flight, departing Thu, Apr 2 from Hartsfield-Jackson Atlanta Intl. to Des Moines Intl., returning Mon, Apr 6, priced at $395 found 1 day ago
Delta
Tue, Jun 16 - Tue, Jun 23
JFK
John F. Kennedy Intl.
DSM
Des Moines Intl.
$395 Roundtrip, found 1 day ago
$395
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 16 from John F. Kennedy Intl. to Des Moines Intl., returning Tue, Jun 23, priced at $395 found 1 day ago

Cheap Flights to Carlisle

Fall in love at first flight with your vacation to Carlisle by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Carlisle on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Carlisle, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Carlisle

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Carlisle with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the DSM airport.

What is the cheapest month to fly to Carlisle?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Carlisle are in May, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Carlisle?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 10 to choose from for your flight to Carlisle.

What airport is best to fly into Carlisle?

When you’re planning your trip to Carlisle, convenience is the name of the game. Luckily, Carlisle Des Moines Intl. Airport is nearby so you can deplane and get going on checking off everything on your Carlisle must-do list.

How much are flights to Carlisle?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Carlisle on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $192, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Carlisle?

The trick to saving a stack of cash on your flight to Carlisle? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $192 right now, why wait?

Carlisle Flight Information
Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Roundtrip price
$191

Last Minute Hotel Deals in Carlisle

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,093 reviews)
Toilet wouldn’t flush, shower wouldn’t drain, valet was incredibly slow, front desk wasn’t very nice. The best part of the stay was the coffee shop and their employees.

Reviewed on Mar 15, 2026

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Hotel Fort Des Moines, Curio Collection by Hilton
Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (1,234 reviews)
Clean and staff is always pleasant. Good breakfast

Reviewed on Mar 16, 2026

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Wildwood Lodge
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,004 reviews)
Great staff. We arrived during a blizzard and they were so accommodating and friendly. We were allowed a later checkout the next day to allow the roads to clear.

Reviewed on Mar 16, 2026

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Home2 Suites by Hilton Des Moines at Drake University
Des Lux Hotel

Des Lux Hotel

3.5 out of 5
800 Locust St Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
9.8/10 Exceptional! (1,042 reviews)
This hotel is top notch. We enjoyed our stay. Everything was clean, the decor is so fun, and the staff was very accommodating. The breakfast buffet offered a wide variety, and was easy to access each morning. The only complaint was the parking was across the street in a garage that was not owned ...

Reviewed on Mar 16, 2026

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Des Lux Hotel
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

3 out of 5
295 South 64th st West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,005 reviews)
.

Reviewed on Mar 15, 2026

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Hyatt Place West Des Moines Jordan Creek
Holiday Inn Downtown - Mercy Area by IHG

Holiday Inn Downtown - Mercy Area by IHG

3 out of 5
1050 6th Ave Des Moines IA
Stay at this hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (1,001 reviews)
Clean room, bar was stocked well, air conditioning wouldn't work quite right it was hot in our room.

Reviewed on Mar 12, 2026

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Holiday Inn Downtown - Mercy Area by IHG
Sonesta Simply Suites Des Moines

Sonesta Simply Suites Des Moines

2.5 out of 5
7625 Office Plaza Dr N West Des Moines IA
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,005 reviews)
The best hotel i have stayed in in the last 2 years. Very clean and spacious. Loved the kitchenette with a full size refrigerator. The water pressure and hot water in the shower were better than I have at home.

Reviewed on Mar 15, 2026

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Sonesta Simply Suites Des Moines
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,754 reviews)
The room didn't really have a closet to hang clothes. And the breakfast buffet did not have any meat which was very disappointing.

Reviewed on Mar 15, 2026

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Days Inn & Suites by Wyndham Des Moines Airport
See all 858 properties in Carlisle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.