Cheap Flights from Des Moines (DSM) to Knoxville (TYS)

Des Moines (DSM) to Knoxville (TYS)

What?! A trip to Knoxville! Well, looks like you'll need a flight from Des Moines pretty soon. Well, unless you'd rather hoof it. And although we agree walking is great exercise, you probably want to get there before the end of the year. Good thing you found us. We can get you an awesome deal on your flight from DSM to TYS.

How do you get the best deal on a ticket from Des Moines to Knoxville?

Hotwire has been doing this for years, so we know a couple ways to snag the best rate on your flight to Knoxville. You can pocket that extra cash for more than just getting from point A to point B with a few simple tips and tricks.

Which days of the week are cheapest to fly?

It pays to be a weekday warrior. Those middle children of the work week, Tuesday and Wednesday, typically have the best rates. Next in line are Thursday and, surprisingly, Saturday. Most people like to fly back from their trip on Sunday so you can save by leaving a day earlier.

Can staying the weekend get me a cheaper ticket?

If you stay through the weekend, generally that return ticket to DSM can be cheaper since you'll be leaving earlier in the week. All those business travelers have less elastic schedules, so that means more savings for you. Good thing to tell your boss if you have a business trip -- wink-wink.

What are shoulder seasons?

Off-peak and shoulder seasons are when most vacationers aren't traveling to certain locations. So when it is chilly, most people head to warmer climates like the Caribbean, Mexico, Hawaii, etc., just like the birds (they had it figured out). But during the summer months, you'll find that Europe gets busy. You may not get the ideal weather, but you'll typically get better prices and avoid the mobs of tourist.

Is that the lowest price?

There are a lot of other people that are longing for a superb deal on a flight from Des Moines to Knoxville. You could miss your opportunity to dial in the time and the flight you wanted.

What is the Hotwire Hot Rate?

The Hotwire Hot Rate is what makes us one of the best bargains out there. You'll get one of our best rates on your flight from Des Moines (DSM) to Knoxville (TYS). You won't know the time and airline until after you book, but with a little risk you can get huge savings.

Book today

Use our guide before you book your upcoming flight from Des Moines to Knoxville. You may have enough coin back in your hand to add something that makes this vacation extra exciting ... or you can pocket the savings and put it toward your next trip out of Des Moines.

^Savings based on all package bookings with Flight + Hotel made on Hotwire.com from January 1, 2018 to December 31, 2018 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.