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Hotels in South Indianapolis

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Baymont by Wyndham Indianapolis South

Baymont by Wyndham Indianapolis South

2.5 out of 5
4402 E Creek View Rd Indianapolis IN
  • 8 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Baymont by Wyndham Indianapolis South
La Quinta Inn & Suites by Wyndham Indianapolis South

La Quinta Inn & Suites by Wyndham Indianapolis South

3 out of 5
5120 Victory Drive Indianapolis IN
  • 4 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the ...
7.8/10 Good! (1,001 reviews)
"This motel is right next to the Interstate. It is very very buy! Lots of semi & car noise all day & all night!! The staff was very nice & efficient."

Reviewed on May 19, 2026

La Quinta Inn & Suites by Wyndham Indianapolis South
Omni Severin Hotel

Omni Severin Hotel

4 out of 5
40 West Jackson Place Indianapolis IN
  • 9 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful ...
9.4/10 Exceptional! (1,004 reviews)
"The room was comfortable but the beds are made with all top sheets and the comforter and sheets are tucked in so tight and short that you literally have to dismantle the bed to sleep in it which is a petty thing but worth pointing out. On another note the staff is exceptionally helpful and friendly. ..."

Reviewed on May 21, 2026

Omni Severin Hotel
The Fontana Hotel

The Fontana Hotel

2.5 out of 5
7304 E 21st St Indianapolis IN
  • 16 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (991 reviews)
"Hotel was clean and quiet."

Reviewed on May 20, 2026

The Fontana Hotel
Ironworks Hotel Indy

Ironworks Hotel Indy

4 out of 5
2721 E 86th Street Indianapolis IN
  • 34 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, free parking, and 4 restaurants. Our guests praise the helpful staff and the clean ...
9.8/10 Exceptional! (1,904 reviews)
"Excellent hotel"

Reviewed on May 20, 2026

Ironworks Hotel Indy
Courtyard by Marriott Indianapolis Downtown

Courtyard by Marriott Indianapolis Downtown

3 out of 5
601 West Washington Street Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9.2/10 Wonderful! (1,134 reviews)
"The only problem I had was, I chose a room with two beds and when I got there, they only gave us one bed and it was very inconvenient. They had no other room.."

Reviewed on May 19, 2026

Courtyard by Marriott Indianapolis Downtown
Best Western Plus Indianapolis North at Pyramids

Best Western Plus Indianapolis North at Pyramids

3 out of 5
9320 N Michigan Rd Indianapolis IN
  • 36 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the ...
8.2/10 Very Good! (1,026 reviews)
"Okay for a night wouldn't stay longer than that. Breakfast better than terrible, but just okay."

Reviewed on May 20, 2026

Best Western Plus Indianapolis North at Pyramids
Sonesta Select Indianapolis Carmel

Sonesta Select Indianapolis Carmel

3 out of 5
37 W 103rd Street Indianapolis IN
  • 38 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the clean rooms in ...
7.8/10 Good! (1,231 reviews)
"Great hotel awesome staff. Kids loved being in the pool. Nice courtyard, had a balcony view. Loved it and we will be back!"

Reviewed on May 21, 2026

Sonesta Select Indianapolis Carmel
Bottleworks Hotel

Bottleworks Hotel

4.5 out of 5
850 Massachusetts Avenue Indianapolis IN
  • 12 min drive from University of Indianapolis
Book a stay at this luxury hotel in Indianapolis. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Bottleworks Hotel
Sheraton Indianapolis City Centre Hotel

Sheraton Indianapolis City Centre Hotel

4 out of 5
31 W Ohio St Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.4/10 Very Good! (1,000 reviews)
"Clean room, pool was quite nice, views spectacular"

Reviewed on May 20, 2026

Sheraton Indianapolis City Centre Hotel
Marriott Indianapolis Downtown

Marriott Indianapolis Downtown

4 out of 5
350 W Maryland St Indianapolis IN
  • 10 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy 2 bars/lounges, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful ...
9.2/10 Wonderful! (1,029 reviews)
"The breakfast was fabulous and much appreciated. Thank you"

Reviewed on May 20, 2026

Marriott Indianapolis Downtown
Courtyard by Marriott Indianapolis at the Capitol

Courtyard by Marriott Indianapolis at the Capitol

3 out of 5
320 N Senate Ave Indianapolis IN
  • 11 min drive from University of Indianapolis
Book a stay at this business-friendly hotel in Indianapolis. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (922 reviews)
"The room was clean and great for our weekend trip. It was comfortable. My children had a great time. Very accommodating when needing extra pillows and blankets. Friendly staff. Great experience."

Reviewed on May 20, 2026

Courtyard by Marriott Indianapolis at the Capitol
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in South Indianapolis

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in South Indianapolis.

Choosing the right hotel in Indiana has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of South Indianapolis’s 2,648 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $94. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great South Indianapolis hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in South Indianapolis. No matter your reason for visiting South Indianapolis, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About South Indianapolis hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can unlock great deals on your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in South Indianapolis for as low as $94.

How many hotels are there in South Indianapolis?

With over 2,648 hotels in South Indianapolis, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $94.

How to find cheap car rentals in South Indianapolis?

Finding a cheap car rental deal in South Indianapolis is as easy as scoring cheap hotels in South Indianapolis. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.