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Hotels in Semmes

Choose from 463 Semmes Hotel Deals

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
  • 31 min drive from Semmes Health Center
Stay at this hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (896 reviews)
We stay here once a month for date night and love it!

Reviewed on Nov 28, 2025

The Admiral, Downtown Historic District
Hampton Inn & Suites Mobile I-65@ Airport Blvd

Hampton Inn & Suites Mobile I-65@ Airport Blvd

3 out of 5
1028 W I-65 Service Rd S Mobile AL
  • 24 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,001 reviews)
Room was great and Kim at the front desk was very personable. The shower was a little finicky but am guessing it was the operator. The hand held came apart while trying to make it work correctly. The breakfast was delicious and the lady making sure everything was fine did a great job. Like that there ...

Reviewed on Nov 28, 2025

Hampton Inn & Suites Mobile I-65@ Airport Blvd
Holiday Inn Mobile-Dwtn/Hist. District by IHG

Holiday Inn Mobile-Dwtn/Hist. District by IHG

3 out of 5
301 Government St Mobile AL
  • 31 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,009 reviews)
Didn’t eat

Reviewed on Nov 25, 2025

Holiday Inn Mobile-Dwtn/Hist. District by IHG
Stay Express Inn & Suites - Mobile AL

Stay Express Inn & Suites - Mobile AL

2.5 out of 5
5170 Motel Ct Mobile AL
  • 34 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Westgate Plaza and Boykin Park ...
7.6/10 Good! (203 reviews)
The room was spacious and clean. There were some areas (e.g., hallway corners) that could have done better with cleaning but I was satisfied with the stay overall.

Reviewed on Nov 25, 2025

Stay Express Inn & Suites - Mobile AL
Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

2.5 out of 5
12000 Cypress Way Spanish Fort AL
  • 48 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,015 reviews)
Great service and clean comfy room

Reviewed on Nov 28, 2025

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
The Battle House Renaissance Mobile Hotel & Spa

The Battle House Renaissance Mobile Hotel & Spa

4 out of 5
26 N Royal St Mobile AL
  • 31 min drive from Semmes Health Center
Book a stay at this luxury hotel in Mobile. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,000 reviews)
Fantastic stay—very clean property that is easy walking to many downtown sites and locations.

Reviewed on Nov 27, 2025

The Battle House Renaissance Mobile Hotel & Spa
Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

3 out of 5
13000 Cypress Way Spanish Fort AL
  • 48 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.8/10 Excellent! (1,005 reviews)
Yes

Reviewed on Nov 28, 2025

Courtyard by Marriott Mobile Daphne/Eastern Shore
Hilton Garden Inn Mobile East Bay / Daphne

Hilton Garden Inn Mobile East Bay / Daphne

3 out of 5
29546 N Main St Daphne AL
  • 49 min drive from Semmes Health Center
Stay at this hotel in Daphne. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,005 reviews)
Short and sweet

Reviewed on Nov 29, 2025

Hilton Garden Inn Mobile East Bay / Daphne
Malaga Inn

Malaga Inn

2.5 out of 5
359 Church Street Mobile AL
  • 31 min drive from Semmes Health Center
Stay at this hotel in Mobile. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.6/10 Excellent! (1,000 reviews)
Great experience.

Reviewed on Nov 26, 2025

Malaga Inn
Tru by Hilton Mobile

Tru by Hilton Mobile

2.5 out of 5
1492 Satchel Paige Drive Mobile AL
  • 28 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (812 reviews)
Positives: exceptional staff (kind, considerate, and helpful), wonderful lobby…neat, clean, variety of snacks and food items to purchase, creative, free coffee all day, and welcoming, comfortable bed, great shower, clean room with several shelves for belongings (loved!), easy to get to elevator and ...

Reviewed on Nov 27, 2025

Tru by Hilton Mobile
La Quinta Inn & Suites by Wyndham Mobile

La Quinta Inn & Suites by Wyndham Mobile

3 out of 5
3650 Airport Blvd Mobile AL
  • 23 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,000 reviews)
Great room and Wonderful staff.

Reviewed on Dec 2, 2025

La Quinta Inn & Suites by Wyndham Mobile
Microtel Inn & Suites by Wyndham Saraland/North Mobile

Microtel Inn & Suites by Wyndham Saraland/North Mobile

2 out of 5
1124 Shelton Beach Rd Saraland AL
  • 22 min drive from Semmes Health Center
Book a stay at this business-friendly hotel in Saraland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,004 reviews)
Very nice staff! Great value! Clean room!

Reviewed on Nov 26, 2025

Microtel Inn & Suites by Wyndham Saraland/North Mobile
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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