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Semmes

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Semmes Flights as Low as $249

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

United
Thu, Jul 9 - Thu, Jul 30
IAH
George Bush Intercontinental
MOB
Mobile Regional
$249 Roundtrip, found 2 hours ago
$249
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Jul 9 from George Bush Intercontinental to Mobile Regional, returning Thu, Jul 30, priced at $249 found 2 hours ago
United
Mon, Jul 27 - Tue, Aug 11
IAH
George Bush Intercontinental
MOB
Mobile Regional
$255 Roundtrip, found 2 hours ago
$255
Roundtrip
found 2 hours ago
Select United flight, departing Mon, Jul 27 from George Bush Intercontinental to Mobile Regional, returning Tue, Aug 11, priced at $255 found 2 hours ago
United
Thu, Jul 9 - Thu, Jul 30
IAH
George Bush Intercontinental
MOB
Mobile Regional
$264 Roundtrip, found 2 hours ago
$264
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Jul 9 from George Bush Intercontinental to Mobile Regional, returning Thu, Jul 30, priced at $264 found 2 hours ago
United
Tue, Sep 22 - Sat, Sep 26
IAD
Washington Dulles Intl.
MOB
Mobile Regional
$269 Roundtrip, found 2 hours ago
$269
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Sep 22 from Washington Dulles Intl. to Mobile Regional, returning Sat, Sep 26, priced at $269 found 2 hours ago
United
Mon, Jul 27 - Tue, Aug 11
IAH
George Bush Intercontinental
MOB
Mobile Regional
$270 Roundtrip, found 2 hours ago
$270
Roundtrip
found 2 hours ago
Select United flight, departing Mon, Jul 27 from George Bush Intercontinental to Mobile Regional, returning Tue, Aug 11, priced at $270 found 2 hours ago
American Airlines
Wed, Jul 8 - Thu, Jul 30
IAH
George Bush Intercontinental
MOB
Mobile Regional
$275 Roundtrip, found 2 hours ago
$275
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Jul 8 from George Bush Intercontinental to Mobile Regional, returning Thu, Jul 30, priced at $275 found 2 hours ago
Delta
Mon, Jul 27 - Tue, Aug 11
IAH
George Bush Intercontinental
MOB
Mobile Regional
$275 Roundtrip, found 2 hours ago
$275
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Jul 27 from George Bush Intercontinental to Mobile Regional, returning Tue, Aug 11, priced at $275 found 2 hours ago
United
Thu, Jul 9 - Thu, Jul 30
IAH
George Bush Intercontinental
MOB
Mobile Regional
$279 Roundtrip, found 2 hours ago
$279
Roundtrip
found 2 hours ago
Select United flight, departing Thu, Jul 9 from George Bush Intercontinental to Mobile Regional, returning Thu, Jul 30, priced at $279 found 2 hours ago
American Airlines
Tue, Aug 4 - Tue, Aug 11
MCI
Kansas City Intl.
MOB
Mobile Regional
$283 Roundtrip, found 2 hours ago
$283
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Tue, Aug 4 from Kansas City Intl. to Mobile Regional, returning Tue, Aug 11, priced at $283 found 2 hours ago
Delta
Wed, Aug 5 - Mon, Aug 10
DCA
Ronald Reagan Washington National
MOB
Mobile Regional
$289 Roundtrip, found 2 hours ago
$289
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Aug 5 from Ronald Reagan Washington National to Mobile Regional, returning Mon, Aug 10, priced at $289 found 2 hours ago
United
Sat, Oct 17 - Tue, Oct 20
MSP
Minneapolis - St. Paul Intl.
MOB
Mobile Regional
$291 Roundtrip, found 5 days ago
$291
Roundtrip
found 5 days ago
Select United flight, departing Sat, Oct 17 from Minneapolis - St. Paul Intl. to Mobile Regional, returning Tue, Oct 20, priced at $291 found 5 days ago
Delta
Wed, Aug 5 - Wed, Aug 26
BWI
Baltimore Washington Intl. Thurgood Marshall
MOB
Mobile Regional
$291 Roundtrip, found 2 hours ago
$291
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Aug 5 from Baltimore Washington Intl. Thurgood Marshall to Mobile Regional, returning Wed, Aug 26, priced at $291 found 2 hours ago
American Airlines
Wed, Jul 29 - Thu, Aug 6
LAX
Los Angeles Intl.
MOB
Mobile Regional
$349 Roundtrip, found 2 hours ago
$349
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Wed, Jul 29 from Los Angeles Intl. to Mobile Regional, returning Thu, Aug 6, priced at $349 found 2 hours ago
Delta
Tue, Jul 28 - Sat, Aug 1
ALB
Albany Intl.
MOB
Mobile Regional
$375 Roundtrip, found 2 hours ago
$375
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Jul 28 from Albany Intl. to Mobile Regional, returning Sat, Aug 1, priced at $375 found 2 hours ago
Delta
Fri, Jul 3 - Tue, Jul 7
ATL
Hartsfield-Jackson Atlanta Intl.
MOB
Mobile Regional
$379 Roundtrip, found 2 hours ago
$379
Roundtrip
found 2 hours ago
Select Delta flight, departing Fri, Jul 3 from Hartsfield-Jackson Atlanta Intl. to Mobile Regional, returning Tue, Jul 7, priced at $379 found 2 hours ago
Delta
Tue, Jun 16 - Tue, Jun 23
TYS
McGhee Tyson
MOB
Mobile Regional
$476 Roundtrip, found 2 hours ago
$476
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Jun 16 from McGhee Tyson to Mobile Regional, returning Tue, Jun 23, priced at $476 found 2 hours ago

Cheap Flights to Semmes

Fall in love at first flight with your vacation to Semmes by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Semmes on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Semmes, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Semmes

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Semmes with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MOB airport.

What is the cheapest month to fly to Semmes?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Semmes are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Semmes?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Semmes.

What airport is best to fly into Semmes?

When you’re planning your trip to Semmes, convenience is the name of the game. Luckily, Semmes Mobile Regional Airport is nearby so you can deplane and get going on checking off everything on your Semmes must-do list.

How much are flights to Semmes?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Semmes on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $249, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Semmes?

The trick to saving a stack of cash on your flight to Semmes? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $249 right now, why wait?

Semmes Flight Information
Destination airport
Mobile Regional
Destination airport IATA code
MOB
Roundtrip price
$249

Last Minute Hotel Deals in Semmes

The Admiral, Downtown Historic District

The Admiral, Downtown Historic District

4 out of 5
251 Government Street Mobile AL
Stay at this hotel in Mobile. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in ...
9.4/10 Exceptional! (1,192 reviews)
"Overall, great fr9nt desk customer service. Good courtesy lemon water and apples. Ice machines were broken on 3 floors, office table in room had coffee stains, and hair on bathroom floor. No free parking or hotel discount for parking, not worth paying more for valet. Nice to offer champagne but maybe ..."

Reviewed on Jun 14, 2026

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The Admiral, Downtown Historic District
Quality Inn & Suites at Airport Blvd I-65

Quality Inn & Suites at Airport Blvd I-65

2.5 out of 5
150 W I-65 Service Road Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Dauphin Street and Mobile Cruise ...
7.8/10 Good! (399 reviews)
"The outside in the lobby of the hotel looked very rundown. The halls and floors and halls were all pretty dirty. It smelled in the hallways. The room was very clean and everything in the room looked like it was in pretty good repair, but the building in the parking lot itself looked pretty old and ..."

Reviewed on Jun 13, 2026

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Quality Inn & Suites at Airport Blvd I-65
La Quinta Inn & Suites by Wyndham Mobile

La Quinta Inn & Suites by Wyndham Mobile

3 out of 5
3650 Airport Blvd Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the helpful staff and the clean ...
8/10 Very Good! (1,003 reviews)
"Clean and great staff"

Reviewed on Jun 11, 2026

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La Quinta Inn & Suites by Wyndham Mobile
Stay Express Inn & Suites - Mobile AL

Stay Express Inn & Suites - Mobile AL

2.5 out of 5
5170 Motel Ct Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Westgate Plaza and Boykin Park ...
7.8/10 Good! (419 reviews)
"Enjoyed everything about my stay!"

Reviewed on Jun 13, 2026

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Stay Express Inn & Suites - Mobile AL
Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore

3 out of 5
12000 Cypress Way Spanish Fort AL
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,021 reviews)
"Breakfast was Good but eggs were cold. Overall not a bad stay."

Reviewed on Jun 14, 2026

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Fairfield Inn & Suites by Marriott Mobile Daphne/ E Shore
Renaissance Mobile Riverview Plaza Hotel

Renaissance Mobile Riverview Plaza Hotel

3.5 out of 5
64 S Water St Mobile AL
Book a stay at this business-friendly hotel in Mobile. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,013 reviews)
"Staff was attentive and property was well maintained, excellent location and amenities."

Reviewed on Jun 11, 2026

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Renaissance Mobile Riverview Plaza Hotel
Courtyard by Marriott Mobile Daphne/Eastern Shore

Courtyard by Marriott Mobile Daphne/Eastern Shore

3 out of 5
13000 Cypress Way Spanish Fort AL
Book a stay at this business-friendly hotel in Spanish Fort. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in ...
9/10 Wonderful! (1,018 reviews)
"Overall experience was great. The hot tub was warm, but the jets didn't work. The front staff were really helpful and did a fantastic job especially on night shift. The bar lady was nice, but not helpful at the bar."

Reviewed on Jun 7, 2026

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Courtyard by Marriott Mobile Daphne/Eastern Shore
Hilton Garden Inn Mobile East Bay / Daphne

Hilton Garden Inn Mobile East Bay / Daphne

3 out of 5
29546 N Main St Daphne AL
Stay at this hotel in Daphne. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. ...
9/10 Wonderful! (1,002 reviews)
"A+ nd would recommend to stay"

Reviewed on Jun 14, 2026

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Hilton Garden Inn Mobile East Bay / Daphne
See all 483 properties in Semmes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.