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Hotels in Santa Isabel

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Choose from 272 Santa Isabel Hotel Deals

Hotel Las Vegas

Hotel Las Vegas

3 out of 5
PR 153, Km 2.9, Santa Isabel
  • 4 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3-star motel in Santa Isabel. Enjoy 24-hour room service, a 24-hour front desk, and daily housekeeping. Our guests praise the helpful staff and ...
7.8/10 Good! (289 reviews)
"Easy access"

Reviewed on Jul 28, 2025

Hotel Las Vegas
Hacienda del Sur

Hacienda del Sur

2 out of 5
Carr 545 KM 1.5, Sector Gabia, Santa Isabel
  • 26 min walk from Carribbean Cinemas Santa Isabel
Stay at this hotel in Santa Isabel. Enjoy free WiFi, free parking, and cable TV channels. Popular attractions Carribbean Cinemas Santa Isabel and Coamo Springs ...
9.4/10 Exceptional! (16 reviews)
"Is a beautiful place and the staff Rosie is a plus."

Reviewed on Jul 12, 2025

Hacienda del Sur
Hilton Ponce Golf & Casino Resort

Hilton Ponce Golf & Casino Resort

4.5 out of 5
1150 Caribe Avenue, Ponce
  • 25 min drive from Carribbean Cinemas Santa Isabel
Stay at this 4.5-star luxury resort in Ponce. Enjoy free WiFi, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff and the clean rooms in ...
8.6/10 Excellent! (1,001 reviews)
"I love it"

Reviewed on Jul 14, 2025

Hilton Ponce Golf & Casino Resort
Caribe Hotel Ponce

Caribe Hotel Ponce

3.5 out of 5
103 Turpo Industrial Park, Ponce
  • 22 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.4/10 Very Good! (1,565 reviews)
"The staff at this hotel was excellent! They went above and beyond to help me and my teen with needs and accommodations after having a horrible time at the airport."

Reviewed on Jul 28, 2025

Caribe Hotel Ponce
Ponce Plaza Hotel & Casino

Ponce Plaza Hotel & Casino

3.5 out of 5
Reina Street, Ponce
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star historic hotel in Ponce. Enjoy free WiFi, a casino, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (1,002 reviews)
"Easy checkin. I saw reviews about parking, but they give a great explanation where the lots were located and how to validate. Beds were comfy and the room was clean. Located in the central area, walkable to plenty of restaurants, shops and bars."

Reviewed on Jul 31, 2025

Ponce Plaza Hotel & Casino
Aloft Ponce Hotel & Casino

Aloft Ponce Hotel & Casino

3.5 out of 5
Street No 2 KM 228.9, Ponce
  • 25 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy free parking, 2 outdoor pools, and 4 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,000 reviews)
"👍"

Reviewed on Jul 31, 2025

Aloft Ponce Hotel & Casino
Holiday Inn Ponce & Tropical Casino by IHG

Holiday Inn Ponce & Tropical Casino by IHG

3.5 out of 5
3315 Ponce By Pass, Ponce
  • 32 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy free WiFi, free parking, and a casino. Our guests praise the helpful staff in our reviews. Popular attractions Carribbean ...
8.6/10 Excellent! (1,006 reviews)
"Bien familiar y cerca de todo...espectacular!"

Reviewed on Jul 31, 2025

Holiday Inn Ponce & Tropical Casino by IHG
The Fox Hotel

The Fox Hotel

3.5 out of 5
6963 Calle Isabel Munoz Rivera, Ponce, Puerto Rico
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star hotel in Ponce. Enjoy 4 restaurants, 3 bars/lounges, and a 24-hour front desk. Popular attractions Plaza of Delights and Parque de Bombas ...
7.2/10 Good! (849 reviews)
"Great place to visit."

Reviewed on Jul 31, 2025

The Fox Hotel
Meliá Century Hotel Ponce

Meliá Century Hotel Ponce

3.5 out of 5
#75 Calle Cristina, Ponce
  • 26 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star business-friendly hotel in Ponce. Enjoy room service, parking (surcharge), and a 24-hour front desk. Popular attractions Parque de Bombas ...
6.4/10 (1,001 reviews)
"No complaint, i love thra hotel!"

Reviewed on Jul 22, 2025

Meliá Century Hotel Ponce
Hotel Nuevo Mejico

Hotel Nuevo Mejico

3.5 out of 5
PR-501, Km 1.4, Ponce, Ponce
  • 31 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3.5-star motel in Ponce. Enjoy free WiFi, free parking, and 24-hour room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.8/10 Good! (636 reviews)
"👍"

Reviewed on Jul 30, 2025

Hotel Nuevo Mejico
Solace by the Sea

Solace by the Sea

3 out of 5
Highway 2 at km 220.1, Ponce
  • 33 min drive from Carribbean Cinemas Santa Isabel
Stay at this 3-star family-friendly hotel in Ponce. Enjoy parking (surcharge), a 24-hour front desk, and daily housekeeping. Popular attractions Playa Cayo Cardona ...
6.2/10 (1,001 reviews)
"Sin microondas ni nevera Sin puerto para calgar electrónicos."

Reviewed on Jul 24, 2025

Solace by the Sea
The Place at the Sea

The Place at the Sea

2 out of 5
3499 Av. Los Meros, Ponce, Ponce
  • 28 min drive from Carribbean Cinemas Santa Isabel
Stay at this aparthotel in Ponce. Enjoy free WiFi, free parking, and a garden. Popular attractions Carribbean Cinemas Ponce Towne and Vicens Coliseum are located ...
9/10 Wonderful! (153 reviews)
"This RV is a greate unit, the only recommendation is the bed is too hard for me but my wife loved."

Reviewed on Jul 30, 2025

The Place at the Sea
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santa Isabel

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $100. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Isabel hotel deals at the last minute.

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Frequently Asked Questions About Santa Isabel hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santa Isabel?

With over 272 hotels in Santa Isabel, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $100.

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Finding a cheap car rental deal in Santa Isabel is as easy as scoring cheap hotels in Santa Isabel. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.