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Top Trending Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455 Santa Cruz

Book a stay at this spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

9/10 Wonderful! (422 reviews)

"The staff were very pleasant and helpful in all areas. Our room was dated and not very well maintained. The furniture was mismatched. Done in two completely different styles that didn’t work together. There was a balcony but there was no furniture on it. A door in the bathroom that separated the ..."

Reviewed on Oct 31, 2026

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Ibis Santa Cruz DE LA Sierra

AVENIDA CRISTOBAL DE MENDOZA Santa Cruz

Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...

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Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz

Book a stay at this luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.