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Hotels in Santa Cruz

Senses Boutique Hotel
Senses Boutique Hotel
3.5 out of 5
Calle 24 de Septiembre, Esq. Sucre No 5, Plaza Principal, Santa Cruz
The price is $50 per night from Sep 19 to Sep 19
Located in the heart of Santa Cruz, this family-friendly hotel is steps from Franco Aleman Cultural Center and Plaza 24 de Septiembre. La Recova Artisan Walk ...
Senses Boutique Hotel
Los Tajibos Hotel And Convention Center
Los Tajibos Hotel And Convention Center
4.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is $125 per night from Oct 1 to Oct 1
Situated in a shopping district, this luxury hotel is 0.9 mi (1.4 km) from Ventura Mall and 2.1 mi (3.3 km) from Plaza 24 de Septiembre. Santa Cruz Zoo and Municipal ...
Los Tajibos Hotel And Convention Center
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is $93 per night from Oct 10 to Oct 10
Situated in the business district, this luxury hotel is 0.6 mi (0.9 km) from Ventura Mall and 2.5 mi (4 km) from Plaza 24 de Septiembre. Santa Cruz Zoo and Municipal ...
Marriott Santa Cruz de la Sierra Hotel
Camino Real Hotel
Camino Real Hotel
4 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is $122 per night from Oct 1 to Oct 1
This family-friendly Santa Cruz hotel is located near the airport, within 2 mi (3 km) of Ventura Mall and Santa Cruz Zoo. Municipal Library and Ethno-folkloric ...
Camino Real Hotel
Radisson Hotel Santa Cruz
Radisson Hotel Santa Cruz
5 out of 5
Avenida Segunda 4, Santa Cruz
The price is $91 per night from Oct 15 to Oct 15
Situated near the airport, this luxury hotel is 1.6 mi (2.5 km) from Ventura Mall and 2.9 mi (4.6 km) from Santa Cruz Zoo. Guembe Biocenter and Municipal Library ...
Radisson Hotel Santa Cruz
Sun Hotel
Sun Hotel
3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
The price is $111 per night from Sep 19 to Sep 19
Situated near the airport, this hotel is 2.1 mi (3.5 km) from AquaLand and within 9 mi (15 km) of Las Brisas Shopping Center and Santa Cruz Zoo. Ventura Mall ...
Sun Hotel
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
The price is $59 per night from Oct 2 to Oct 2
Situated in the entertainment district, this hotel is 1 mi (1.6 km) from Santa Cruz Zoo and 1.9 mi (3 km) from Plaza 24 de Septiembre. Ventura Mall and Municipal ...
TRYP by Wyndham Santa Cruz
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
4.5 out of 5
Canal Isuto, Los Pachio, Barrio 2 De Abril, Santa Cruz
The price is $95 per night from Oct 2 to Oct 2
Situated in Santa Cruz, this luxury hotel is within 2 mi (3 km) of Ventura Mall, Las Brisas Shopping Center, and Santa Cruz Zoo. Municipal Library and Arenal ...
Swissôtel Santa Cruz De La Sierra
Buganvillas Hotel Suites & Spa
Buganvillas Hotel Suites & Spa
4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
This family-friendly hotel is located in the city center, within 3 mi (5 km) of Guarani Nandereko Nomai Art and Culture Center and Plaza 24 de Septiembre. La ...
Buganvillas Hotel Suites & Spa
Hotel Rio Selva Resort Santa Cruz
Hotel Rio Selva Resort Santa Cruz
3 out of 5
Calle Azucenas #15, Barrio Sirari, Warnes, Santa Cruz
Set in Warnes, this family-friendly hotel is within 9 mi (15 km) of Warnes Plaza, AquaLand, and Palestina Church. Santa Cruz Zoo and Plaza 24 de Septiembre are ...
Hotel Rio Selva Resort Santa Cruz
Hotel LP Equipetrol
Hotel LP Equipetrol
3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
The price is $54 per night from Sep 19 to Sep 19
Situated in the entertainment district, this hotel is 0.8 mi (1.3 km) from Ventura Mall and 2.3 mi (3.7 km) from Plaza 24 de Septiembre. Santa Cruz Zoo and Municipal ...
Hotel LP Equipetrol
Hampton by Hilton Santa Cruz
Hampton by Hilton Santa Cruz
3.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
The price is $81 per night from Sep 21 to Sep 21
Situated in the business district, this hotel is within 2 mi (3 km) of Ventura Mall, Santa Cruz Zoo, and Municipal Library. Las Brisas Shopping Center and Ethno-folkloric ...
Hampton by Hilton Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Santa Cruz 

2021 is the year you’ve decided to satisfy that travel urge. This trip you plan to mix it up a bit. You want a great place to stay, but also plan to hit up the places most tourists don’t even know about. So, can you get a great hotel in Santa Cruz for a steal? No doubt, and you’ll have cash left over to do this trip up the way you want.

This must be the place

Just how you like to live life a little differently, we do hotel bookings against the grain. You won’t have to decide between staying at one of the best hotels in Santa Cruz or scoring reservations at one of the hippest restaurants in Santa Cruz. With Hotwire, you can have both, and then some. After booking your place, you’ll have extra cash to tack on last-minute concert tickets, check out those off-beat sites, and do a little souvenir shopping because you’re all about setting your social feeds on fire, without burning your bank account.

Let us help you deal

You’re someone that likes to game the system, so choose the Hotwire Hot Rate. You’ll get the Santa Cruz hotel you’ve been eyeing at a price that’ll make you check twice to see if it’s real. Yes, the price is right. We have several ways for you to pick your preferred pad, and no matter which way you go, you’ll snag a hotel that you’ll brag about. Filter by:

  • Hotwire Hot Rate: You get some of the best hotels in Santa Cruz at ridiculously cheap rates—you’ll find out the hotel name after you book. You might even score a 4-star hotel at a 2-star price.

  • Price: Have a tight budget this go around? No worries. We have hotels for all price ranges, with rooms starting at $50.

  • Amenities: Heated pool? Maybe a private balcony with a view? Find the hotel that your dreams are made of.

Make your best year yet, and snap up one of the 166 killer Santa Cruz hotel deals and be the person that travel bloggers come to for advice.