Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Edwardsville Vacations

Pack those stellar shades. We have Edwardsville vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Edwardsville – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Edwardsville vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Edwardsville

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Edwardsville vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Edwardsville well.

Edwardsville Flight + Hotel packages

Top Hotel Deals

See all 221 Hotels in Edwardsville
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

5224 Commerce Parkway, Edwardsville
    2.5 out of 5.0
     
     

    Situated in Edwardsville, this hotel is within 9 mi (15 km) of Lewis and Clark Interpretive Center, Lewis and Clark Confluence Tower, and Gateway Fun Park. Splash ...

    Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City$104

    Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City$104
    Comfort Inn Edwardsville

    Comfort Inn Edwardsville

    3080 S State Route 157, Edwardsville
      2.5 out of 5.0
       
       

      Situated in Edwardsville, this hotel is 2.7 mi (4.4 km) from Edwardsville Arts Center and within 6 mi (10 km) of The Gardens at SIUE and St. Andrew's Episcopal ...

      Comfort Inn Edwardsville$89

      Comfort Inn Edwardsville$89
      Holiday Inn Express & Suites Edwardsville

      Holiday Inn Express & Suites Edwardsville

      1000 Plummer Drive, Edwardsville
        2.5 out of 5.0
         
         

        Located in the heart of Edwardsville, this hotel is 0.4 mi (0.6 km) from Edwardsville Arts Center and within 3 mi (5 km) of The Gardens at SIUE and St. Andrew's ...

        Holiday Inn Express & Suites Edwardsville$117

        Holiday Inn Express & Suites Edwardsville$117
        Country Hearth Inn & Suites

        Country Hearth Inn & Suites

        1013 Plummer Drive, Edwardsville
          2.5 out of 5.0
           
           

          Situated in Edwardsville, this hotel is 0.4 mi (0.7 km) from Edwardsville Arts Center and within 3 mi (5 km) of The Gardens at SIUE and St. Andrew's Episcopal ...

          City Place St. Louis - Downtown Hotel

          City Place St. Louis - Downtown Hotel

          200 North 4th Street, St. Louis
            3.5 out of 5.0
             
             

            This 29-story St. Louis hotel is 4 blocks from Busch Stadium, 6 blocks from the Edward Jones Dome and the Lumiere Place Casino, and less than 1 mile from Scottrade ...

            City Place St. Louis - Downtown Hotel$91

            City Place St. Louis - Downtown Hotel$91
            Drury Plaza Hotel St. Louis at the Arch

            Drury Plaza Hotel St. Louis at the Arch

            2 South 4th Street, St. Louis
              3.0 out of 5.0
               
               

              Located in Downtown St. Louis, this hotel is within a 10-minute walk of Old Courthouse and Busch Stadium. Gateway Arch and Dome at America’s Center are also ...

              Red Lion Hotel St Louis City Center

              Red Lion Hotel St Louis City Center

              400 S 14th St, St. Louis
                3.5 out of 5.0
                 
                 

                This historic 13-story St. Louis hotel is 1 block from Scottrade/Peabody Opera House Complex, 3 blocks from Union Station, and 5 blocks from Busch Stadium. The ...

                Red Lion Hotel St Louis City Center$97

                Red Lion Hotel St Louis City Center$97
                Clayton Plaza Hotel

                Clayton Plaza Hotel

                7750 Carondelet Avenue, St. Louis
                  3.5 out of 5.0
                   
                   

                  Surrounded by businesses, restaurants, and residences, the Clayton Plaza Hotel is 4 miles from Forest Park and the acclaimed St. Louis Zoo. Downtown St. Louis ...

                  Clayton Plaza Hotel$100

                  Clayton Plaza Hotel$100
                  The Parkway Hotel

                  The Parkway Hotel

                  4550 Forest Park Ave, St. Louis
                    3.0 out of 5.0
                     
                     

                    Located in Central West End, this hotel is within a 15-minute walk of Barnes Jewish Hospital, World Chess Hall of Fame, and Cathedral Basilica of St. Louis. ...

                    The Parkway Hotel$107

                    The Parkway Hotel$107
                    Motel 6 Hazelwood

                    Motel 6 Hazelwood

                    5781 Campus Ct, Hazelwood
                      2.0 out of 5.0
                       
                       

                      Situated near the airport, this motel is within 6 mi (10 km) of St. Louis Mills Mall, James S. McDonnell Prologue Room, and Payne-Gentry Historical House. Westport ...

                      Motel 6 Hazelwood$36

                      Motel 6 Hazelwood$36

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.