Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Des Moines Vacations

Pack those stellar shades. We have Des Moines vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to Des Moines – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with Des Moines vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to Des Moines

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great Des Moines vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows Des Moines well.

Top Hotel Deals

See all 1,736 Hotels in New Mexico
Super 8 by Wyndham Albuquerque Airport

Super 8 by Wyndham Albuquerque Airport

2231 Yale Blvd SE, Albuquerque
    2.5 out of 5.0
     
     

    Situated near the airport, this hotel is 0.7 mi (1.1 km) from Puerto Del Sol Golf Course and 2.6 mi (4.2 km) from National Hispanic Cultural Center. Isotopes ...

    Super 8 by Wyndham Albuquerque Airport$55

    Super 8 by Wyndham Albuquerque Airport$55
    Nativo Lodge

    Nativo Lodge

    6000 Pan American Fwy NE, Albuquerque
      3.0 out of 5.0
       
       

      Located in the Balloon Fiesta Park district, Nativo Lodge is a 15-minute drive from Albuquerque International Sunport. Nativo Lodge is also only a 10 minutes ...

      Nativo Lodge$71

      Nativo Lodge$71
      MCM Elegante

      MCM Elegante

      2020 Menaul Blvd Ne, Albuquerque
        3.0 out of 5.0
         
         

        The midtown MCM Elegante is about 1 mile from University of New Mexico and 4 miles from Old Town Albuquerque's museums, galleries, and shops. Albuquerque airport ...

        MCM Elegante$88

        MCM Elegante$88
        Hyatt Place Albuquerque Airport

        Hyatt Place Albuquerque Airport

        1400 Sunport Place SE, Albuquerque
          3.0 out of 5.0
           
           

          Hyatt Place Albuquerque Airport is a 2-minute drive from the terminals and 10 minutes from the historic city center. Within 25 minutes, guests can be driving ...

          Hyatt Place Albuquerque Airport$77

          Hyatt Place Albuquerque Airport$77
          Ramada by Wyndham Albuquerque Airport

          Ramada by Wyndham Albuquerque Airport

          2300 Yale Blvd Se, Albuquerque
            2.0 out of 5.0
             
             

            Located in the heart of Albuquerque, this hotel is 0.7 mi (1.2 km) from Puerto Del Sol Golf Course and 2.7 mi (4.3 km) from National Hispanic Cultural Center. ...

            Ramada by Wyndham Albuquerque Airport$59

            Ramada by Wyndham Albuquerque Airport$59
            Best Western Plus Rio Grande Inn

            Best Western Plus Rio Grande Inn

            1015 Rio Grande Blvd Nw, Albuquerque
              3.0 out of 5.0
               
               

              Situated in the historical district, this hotel is within a 15-minute walk of Albuquerque Museum and Old Town Plaza. New Mexico Museum of Natural History and ...

              Best Western Plus Rio Grande Inn$97

              Best Western Plus Rio Grande Inn$97
              Days Inn by Wyndham Midtown ABQ

              Days Inn by Wyndham Midtown ABQ

              2120 Menaul Blvd Ne, Albuquerque
                2.0 out of 5.0
                 
                 

                Located in Downtown Albuquerque, this hotel is 1.4 mi (2.3 km) from Maxwell Museum of Anthropology and 2.2 mi (3.6 km) from Indian Pueblo Cultural Center. Tricklock ...

                Days Inn by Wyndham Midtown ABQ$33

                Days Inn by Wyndham Midtown ABQ$33
                Hotel Albuquerque at Old Town

                Hotel Albuquerque at Old Town

                800 Rio Grande Blvd Nw, Albuquerque
                  3.5 out of 5.0
                   
                   

                  Situated in the historical district, this hotel is within a 10-minute walk of Albuquerque Museum and Old Town Plaza. New Mexico Museum of Natural History and ...

                  Hotel Albuquerque at Old Town$97

                  Hotel Albuquerque at Old Town$97
                  Wyndham Albuquerque Hotel & Conference Center

                  Wyndham Albuquerque Hotel & Conference Center

                  2500 Carlisle Blvd Ne, Albuquerque
                    3.5 out of 5.0
                     
                     

                    Located in the Midtown business district, this Albuquerque hotel is conveniently accessible to I-40 and I-25. The University of New Mexico and Albuquerque International ...

                    Wyndham Albuquerque Hotel & Conference Center$69

                    Wyndham Albuquerque Hotel & Conference Center$69
                    Sheraton Albuquerque Airport Hotel

                    Sheraton Albuquerque Airport Hotel

                    2910 Yale Blvd Se, Albuquerque
                      3.5 out of 5.0
                       
                       

                      Situated in the business district, this hotel is close to UNM, KAFB, Sandia National Labs, Mesa Del Sol and all local attractions to include University Stadium ...

                      Sheraton Albuquerque Airport Hotel$80

                      Sheraton Albuquerque Airport Hotel$80