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Santa Cruz

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Santa Cruz Flights as Low as $187

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Aerolineas Argentinas
Tue, Nov 18 - Sat, Nov 22
EZE
Ministro Pistarini Intl.
SCL
Arturo Merino Benitez
$187 Roundtrip, found 17 hours ago
$187
Roundtrip
found 17 hours ago
Select Aerolineas Argentinas flight, departing Tue, Nov 18 from Ministro Pistarini Intl. to Arturo Merino Benitez, returning Sat, Nov 22, priced at $187 found 17 hours ago
Aerolineas Argentinas
Wed, Dec 10 - Mon, Dec 15
AEP
Aeroparque Jorge Newbery
SCL
Arturo Merino Benitez
$187 Roundtrip, found 14 hours ago
$187
Roundtrip
found 14 hours ago
Select Aerolineas Argentinas flight, departing Wed, Dec 10 from Aeroparque Jorge Newbery to Arturo Merino Benitez, returning Mon, Dec 15, priced at $187 found 14 hours ago
Aerolineas Argentinas
Thu, Dec 11 - Thu, Dec 18
AEP
Aeroparque Jorge Newbery
SCL
Arturo Merino Benitez
$209 Roundtrip, found 14 hours ago
$209
Roundtrip
found 14 hours ago
Select Aerolineas Argentinas flight, departing Thu, Dec 11 from Aeroparque Jorge Newbery to Arturo Merino Benitez, returning Thu, Dec 18, priced at $209 found 14 hours ago
Jetsmart SPA
Thu, Dec 11 - Thu, Dec 18
AEP
Aeroparque Jorge Newbery
SCL
Arturo Merino Benitez
$239 Roundtrip, found 14 hours ago
$239
Roundtrip
found 14 hours ago
Select Jetsmart SPA flight, departing Thu, Dec 11 from Aeroparque Jorge Newbery to Arturo Merino Benitez, returning Thu, Dec 18, priced at $239 found 14 hours ago
SKY AIRLINE
Wed, Nov 19 - Sat, Nov 22
EZE
Ministro Pistarini Intl.
SCL
Arturo Merino Benitez
$241 Roundtrip, found 17 hours ago
$241
Roundtrip
found 17 hours ago
Select SKY AIRLINE flight, departing Wed, Nov 19 from Ministro Pistarini Intl. to Arturo Merino Benitez, returning Sat, Nov 22, priced at $241 found 17 hours ago
KLM
Fri, Oct 24 - Sun, Oct 26
EZE
Ministro Pistarini Intl.
SCL
Arturo Merino Benitez
$243 Roundtrip, found 10 hours ago
$243
Roundtrip
found 10 hours ago
Select KLM flight, departing Fri, Oct 24 from Ministro Pistarini Intl. to Arturo Merino Benitez, returning Sun, Oct 26, priced at $243 found 10 hours ago
SKY AIRLINE
Sat, Oct 18 - Sun, Oct 19
MVD
Carrasco Intl.
SCL
Arturo Merino Benitez
$243 Roundtrip, found 1 day ago
$243
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Sat, Oct 18 from Carrasco Intl. to Arturo Merino Benitez, returning Sun, Oct 19, priced at $243 found 1 day ago
LATAM Airlines Group
Sat, May 16 - Sat, May 30
EZE
Ministro Pistarini Intl.
SCL
Arturo Merino Benitez
$252 Roundtrip, found 5 hours ago
$252
Roundtrip
found 5 hours ago
Select LATAM Airlines Group flight, departing Sat, May 16 from Ministro Pistarini Intl. to Arturo Merino Benitez, returning Sat, May 30, priced at $252 found 5 hours ago
Arajet
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$458 Roundtrip, found 3 hours ago
$458
Roundtrip
found 3 hours ago
Select Arajet flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $458 found 3 hours ago
American Airlines
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$472 Roundtrip, found 3 hours ago
$472
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $472 found 3 hours ago
United
Mon, Oct 27 - Sun, Nov 2
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$489 Roundtrip, found 11 hours ago
$489
Roundtrip
found 11 hours ago
Select United flight, departing Mon, Oct 27 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Sun, Nov 2, priced at $489 found 11 hours ago
Copa
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$490 Roundtrip, found 3 hours ago
$490
Roundtrip
found 3 hours ago
Select Copa flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $490 found 3 hours ago
United
Thu, Dec 11 - Sat, Dec 27
MCO
Orlando Intl.
SCL
Arturo Merino Benitez
$508 Roundtrip, found 1 day ago
$508
Roundtrip
found 1 day ago
Select United flight, departing Thu, Dec 11 from Orlando Intl. to Arturo Merino Benitez, returning Sat, Dec 27, priced at $508 found 1 day ago
Delta
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$577 Roundtrip, found 3 hours ago
$577
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $577 found 3 hours ago
avianca
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$636 Roundtrip, found 3 hours ago
$636
Roundtrip
found 3 hours ago
Select avianca flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $636 found 3 hours ago
Air Canada
Tue, Oct 28 - Tue, Nov 4
SJU
Luis Munoz Marin Intl.
SCL
Arturo Merino Benitez
$2,353 Roundtrip, found 3 hours ago
$2,353
Roundtrip
found 3 hours ago
Select Air Canada flight, departing Tue, Oct 28 from Luis Munoz Marin Intl. to Arturo Merino Benitez, returning Tue, Nov 4, priced at $2,353 found 3 hours ago

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Santa Cruz

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in November, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $187, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $187 right now, why wait?

Santa Cruz Flight Information
Destination airport
Arturo Merino Benitez
Destination airport IATA code
SCL
Roundtrip price
$187

Last Minute Hotel Deals in Santa Cruz

Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (326 reviews)
"No table in room, only one chair in room. Not able to sit with my wife to order a drink from the bar since we had no place to sit or place our bar food (no table)"

Reviewed on Sep 25, 2025

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Santa Cruz Plaza
Hotel Cava Colchagua

Hotel Cava Colchagua

4 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
Stay at this 4-star spa hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and an attached winery. Popular attractions Laura Hartwig Winery and Casino ...
8.8/10 Excellent! (166 reviews)
"Very interesting barrel rooms. Clever. Steep steps to get to the bathroom which isn’t ideal when tired but it’s a novelty hotel so it was fun."

Reviewed on Aug 27, 2025

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Hotel Cava Colchagua
TerraViña

TerraViña

3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Laura Hartwig Winery and Plaza ...
9.2/10 Wonderful! (200 reviews)
"Beautiful setting next to a vineyard, with a pool. Restaurant on-site. Well maintained grass. Clean room with nice bedsheets and a good A/C. Good breakfast in a beautiful setting. Very nice views to the vineyard from the room and the restaurant. The explanation given about charging IVA to Chileans ..."

Reviewed on Sep 20, 2025

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TerraViña
La Perla Hotel

La Perla Hotel

3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza ...
9/10 Wonderful! (97 reviews)
"Nice stay"

Reviewed on Apr 13, 2025

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La Perla Hotel
Hotel Vendimia Parador

Hotel Vendimia Parador

3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
Stay at this 3-star hotel in Santa Cruz. Enjoy free WiFi, free parking, and free grocery shopping service. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (76 reviews)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service."

Reviewed on Mar 24, 2025

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Hotel Vendimia Parador
Colchagua Tiny Lodge

Colchagua Tiny Lodge

3 out of 5
I-350 kilometro 4,5, Santa Cruz, O'Higgins
Stay at this 3-star cabin in Santa Cruz. Enjoy free WiFi, free parking, and private hot tubs. Popular attractions Lapostolle Clos Apalta Winery and Bodega Viña ...
10/10 Exceptional! (3 reviews)
"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10."

Reviewed on Oct 2, 2025

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Colchagua Tiny Lodge
Casa Calfu

Casa Calfu

3 out of 5
21 de Mayo 552, Santa Cruz, OHiggins
Stay at this 3-star B&B in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Plaza de Armas and Museo de Colchagua are located ...
9.6/10 Exceptional! (61 reviews)
"This is a really charming bed and breakfast. It is in a secure area and behind a locked gate. They have many amenities that I did not make use of such as a a pool and hot tub. The breakfast was excellent. My room had a very small private terrace with seats for two. There was also a larger terrace ..."

Reviewed on Mar 24, 2025

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Casa Calfu
Hotel Boutique Grand Cru

Hotel Boutique Grand Cru

3 out of 5
Chomedahue, cruce El Guindo, 13, Santa Cruz, O'Higgins
Stay at this 3-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Museo de Colchagua and Plaza de Armas are located ...
10/10 Exceptional! (5 reviews)
"We had such a wonderful stay! The staff was so attentive and the room was impeccable! I highly recommend this hotel."

Reviewed on Apr 14, 2025

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Hotel Boutique Grand Cru
See all 56 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.