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Santa Cruz

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Santa Cruz Flights as Low as $210

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

LATAM Airlines Group
Aerolineas Argentinas
Copa
Copa
LATAM Airlines Group
Copa
Avianca
Avianca
Avianca
Avianca
Avianca
Alaska Airlines
JetBlue Airways
JetBlue Airways
JetBlue Airways
Alaska Airlines

Cheap Flights to Santa Cruz

Fall in love at first flight with your vacation to Santa Cruz by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Santa Cruz on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Santa Cruz, the good times start rolling. So buckle up, you’re in for a fun ride.

Just the right flight

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Santa Cruz with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the SCL airport.

Frequently Asked Questions About flights to Santa Cruz

What is the cheapest month to fly to Santa Cruz?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Santa Cruz are in March, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Santa Cruz?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Santa Cruz.

What airport is best to fly into Santa Cruz?

When you’re planning your trip to Santa Cruz, convenience is the name of the game. Luckily, Santa Cruz Arturo Merino Benitez Airport is nearby so you can deplane and get going on checking off everything on your Santa Cruz must-do list.

How much are flights to Santa Cruz?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Santa Cruz on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $210, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Santa Cruz?

The trick to saving a stack of cash on your flight to Santa Cruz? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $210 right now, why wait?

Can I fly to Santa Cruz right now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to  right now?” When it’s time to book your flight, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

Last Minute Hotel Deals in Santa Cruz

Hostal del Mimbre
Hostal del Mimbre
2.5 out of 5
Las Loicas 382, Santa Cruz, O'Higgins Region, Santa Cruz
The price is $36 per night from Dec 4 to Dec 4
Situated in Santa Cruz, this hostal is within a 10-minute walk of Museo de Colchagua and Plaza de Armas. Casino Colchagua is 1.2 mi (2 km) away.
Hostal del Mimbre
Santa Cruz Plaza
Santa Cruz Plaza
4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
The price is $169 per night from Dec 16 to Dec 16
This family-friendly Santa Cruz hotel is located in the historical district, just steps from Plaza de Armas and Museo de Colchagua. Casino Colchagua is 1.4 mi ...
Santa Cruz Plaza
TerraViña
TerraViña
3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
The price is $126 per night from Dec 5 to Dec 5
Situated in Santa Cruz, this hotel is within 3 mi (5 km) of Plaza de Armas, Museo de Colchagua, and Casino Colchagua. MontGras Winery and Hacienda El Huique ...
TerraViña
Hotel Cava Colchagua
Hotel Cava Colchagua
2.5 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
The price is $146 per night from Dec 13 to Dec 13
Located in the heart of Santa Cruz, this spa hotel is within 3 mi (5 km) of Plaza de Armas, Museo de Colchagua, and Casino Colchagua. MontGras Winery and Hacienda ...
Hotel Cava Colchagua
Hotel Vendimia Parador
Hotel Vendimia Parador
3 out of 5
Camino Los Boldos SN, Santa Cruz, O'Higgins
The price is $120 per night from Dec 5 to Dec 5
This family-friendly Santa Cruz hotel is located in the suburbs, within 2 mi (3 km) of Plaza de Armas and Museo de Colchagua. Casino Colchagua is 2.4 mi (3.9 ...
Hotel Vendimia Parador
La Perla Hotel
La Perla Hotel
3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
The price is $179 per night from Dec 5 to Dec 5
Situated in the suburbs, this hotel is within 2 mi (3 km) of Museo de Colchagua, Plaza de Armas, and Casino Colchagua. MontGras Winery and Hacienda El Huique ...
La Perla Hotel
Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Boutique Solaz Bella Vista de Colchagua
3 out of 5
San Pedro de Callihue Lote 5 J, Santa Cruz, O'Higgins
The price is $111 per night from Dec 23 to Dec 23
Situated in the mountains, this spa hotel is within 9 mi (15 km) of Plaza de Armas, Museo de Colchagua, and Casino Colchagua. MontGras Winery is 12 mi (19.3 ...
Hotel Boutique Solaz Bella Vista de Colchagua
Casa Calfu Hostal B&B
Casa Calfu Hostal B&B
3 out of 5
21 de Mayo 552, Santa Cruz, OHiggins
The price is $99 per night from Dec 29 to Dec 29
Situated in Santa Cruz, this bed & breakfast is within a 15-minute walk of Plaza de Armas and Museo de Colchagua. Casino Colchagua is 1.8 mi (2.9 km) away.
Casa Calfu Hostal B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.