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Cheap round-trip flights to South America

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

About South America

Hotwire offers flights to South America to meet every traveler's needs. Whatever your flight need - Hotwire has the flight for you. So choose from flights to South America or destinations around the world and discover how easy it is to make your flight reservations on Hotwire.

Last Minute Hotel Deals in South America

See all 36,878 Properties in South America
Rochester Classic

Rochester Classic

Esmeralda 542, Buenos Aires
    3.5 out of 5.0
     
     

    Located in the heart of Buenos Aires, this elegant hotel is 2 blocks from Florida Street shopping, dining, and entertainment.

    Rochester Classic$59

    Rochester Classic$59
    Regal Pacific Buenos Aires

    Regal Pacific Buenos Aires

    25 De Mayo, 764, Buenos Aires
      4.5 out of 5.0
       
       

      Regal Pacific Buenos Aires is a 5-minute walk from the gleaming high-rises and posh steakhouses lining the Puerto Madero waterfront. Guests can shop for tango ...

      Regal Pacific Buenos Aires$119

      Regal Pacific Buenos Aires$119
      Hotel Concorde

      Hotel Concorde

      25 De Mayo 630, Buenos Aires
        3.0 out of 5.0
         
         

        Located in El Centro, this hotel is within a 15-minute walk of Luna Park, Plaza de Mayo, and Casa Rosada. Plaza San Martin and Buenos Aires Metropolitan Cathedral ...

        Hotel ConcordeGet Rates

        Galerías Hotel

        Galerías Hotel

        San Antonio 65, Santiago
          4.0 out of 5.0
           
           

          Located in Santiago Center, this hotel is within a 10-minute walk of San Francisco Church, Palacio de la Moneda, and Plaza de la Constitucion. Santiago Town ...

          Galerías Hotel$89

          Galerías Hotel$89