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Depew

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Depew Flights as Low as $98

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Frontier Airlines
Wed, Jul 15 - Thu, Aug 6
ATL
Hartsfield-Jackson Atlanta Intl.
BUF
Buffalo Niagara Intl.
$98 Roundtrip, found 1 day ago
$98
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Jul 15 from Hartsfield-Jackson Atlanta Intl. to Buffalo Niagara Intl., returning Thu, Aug 6, priced at $98 found 1 day ago
Frontier Airlines
Sun, Jul 5 - Thu, Jul 9
ATL
Hartsfield-Jackson Atlanta Intl.
BUF
Buffalo Niagara Intl.
$101 Roundtrip, found 3 days ago
$101
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Jul 5 from Hartsfield-Jackson Atlanta Intl. to Buffalo Niagara Intl., returning Thu, Jul 9, priced at $101 found 3 days ago
Delta
Wed, Jul 15 - Thu, Aug 6
ATL
Hartsfield-Jackson Atlanta Intl.
BUF
Buffalo Niagara Intl.
$139 Roundtrip, found 1 day ago
$139
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 15 from Hartsfield-Jackson Atlanta Intl. to Buffalo Niagara Intl., returning Thu, Aug 6, priced at $139 found 1 day ago
Frontier Airlines
Tue, Jul 21 - Wed, Aug 5
MCO
Orlando Intl.
BUF
Buffalo Niagara Intl.
$143 Roundtrip, found 15 hours ago
$143
Roundtrip
found 15 hours ago
Select Frontier Airlines flight, departing Tue, Jul 21 from Orlando Intl. to Buffalo Niagara Intl., returning Wed, Aug 5, priced at $143 found 15 hours ago
JetBlue Airways
Tue, Jul 14 - Wed, Jul 15
JFK
John F. Kennedy Intl.
BUF
Buffalo Niagara Intl.
$153 Roundtrip, found 15 hours ago
$153
Roundtrip
found 15 hours ago
Select JetBlue Airways flight, departing Tue, Jul 14 from John F. Kennedy Intl. to Buffalo Niagara Intl., returning Wed, Jul 15, priced at $153 found 15 hours ago
JetBlue Airways
Tue, Jun 30 - Wed, Jul 8
BOS
Logan Intl.
BUF
Buffalo Niagara Intl.
$217 Roundtrip, found 15 hours ago
$217
Roundtrip
found 15 hours ago
Select JetBlue Airways flight, departing Tue, Jun 30 from Logan Intl. to Buffalo Niagara Intl., returning Wed, Jul 8, priced at $217 found 15 hours ago
American Airlines
Tue, Jun 30 - Wed, Jul 8
BOS
Logan Intl.
BUF
Buffalo Niagara Intl.
$217 Roundtrip, found 15 hours ago
$217
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Tue, Jun 30 from Logan Intl. to Buffalo Niagara Intl., returning Wed, Jul 8, priced at $217 found 15 hours ago
JetBlue Airways
Wed, Jul 8 - Wed, Jul 15
ILM
Wilmington Intl.
BUF
Buffalo Niagara Intl.
$238 Roundtrip, found 18 hours ago
$238
Roundtrip
found 18 hours ago
Select JetBlue Airways flight, departing Wed, Jul 8 from Wilmington Intl. to Buffalo Niagara Intl., returning Wed, Jul 15, priced at $238 found 18 hours ago
Frontier Airlines
Wed, Jul 8 - Tue, Jul 21
BWI
Baltimore Washington Intl. Thurgood Marshall
BUF
Buffalo Niagara Intl.
$246 Roundtrip, found 5 days ago
$246
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, Jul 8 from Baltimore Washington Intl. Thurgood Marshall to Buffalo Niagara Intl., returning Tue, Jul 21, priced at $246 found 5 days ago
Frontier Airlines
Wed, Aug 5 - Tue, Aug 11
CLT
Charlotte-Douglas Intl.
BUF
Buffalo Niagara Intl.
$246 Roundtrip, found 6 days ago
$246
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Wed, Aug 5 from Charlotte-Douglas Intl. to Buffalo Niagara Intl., returning Tue, Aug 11, priced at $246 found 6 days ago
Bargain Flight
Wed, Sep 23 - Fri, Sep 25
MCO
Orlando Intl.
BUF
Buffalo Niagara Intl.
$251 Roundtrip, found 5 days ago
$251
Roundtrip
found 5 days ago
Select Bargain Flight flight, departing Wed, Sep 23 from Orlando Intl. to Buffalo Niagara Intl., returning Fri, Sep 25, priced at $251 found 5 days ago
Delta
Tue, Jul 14 - Mon, Jul 20
BGR
Bangor Intl.
BUF
Buffalo Niagara Intl.
$316 Roundtrip, found 1 day ago
$316
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jul 14 from Bangor Intl. to Buffalo Niagara Intl., returning Mon, Jul 20, priced at $316 found 1 day ago
Delta
Tue, Oct 27 - Tue, Nov 3
DAB
Daytona Beach Intl.
BUF
Buffalo Niagara Intl.
$327 Roundtrip, found 19 hours ago
$327
Roundtrip
found 19 hours ago
Select Delta flight, departing Tue, Oct 27 from Daytona Beach Intl. to Buffalo Niagara Intl., returning Tue, Nov 3, priced at $327 found 19 hours ago
Delta
Tue, Jun 30 - Sat, Jul 4
SEA
Seattle - Tacoma Intl.
BUF
Buffalo Niagara Intl.
$330 Roundtrip, found 1 day ago
$330
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Jun 30 from Seattle - Tacoma Intl. to Buffalo Niagara Intl., returning Sat, Jul 4, priced at $330 found 1 day ago
Alaska Airlines
Thu, Jul 2 - Fri, Jul 24
SEA
Seattle - Tacoma Intl.
BUF
Buffalo Niagara Intl.
$723 Roundtrip, found 1 day ago
$723
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Thu, Jul 2 from Seattle - Tacoma Intl. to Buffalo Niagara Intl., returning Fri, Jul 24, priced at $723 found 1 day ago
Sun Country Airlines
Thu, Jul 2 - Mon, Jul 6
SEA
Seattle - Tacoma Intl.
BUF
Buffalo Niagara Intl.
$873 Roundtrip, found 1 day ago
$873
Roundtrip
found 1 day ago
Select Sun Country Airlines flight, departing Thu, Jul 2 from Seattle - Tacoma Intl. to Buffalo Niagara Intl., returning Mon, Jul 6, priced at $873 found 1 day ago

Cheap Flights to Depew

Fall in love at first flight with your vacation to Depew by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Depew on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Depew, the good times start rolling. So buckle up, you’re in for a fun ride.

Frequently Asked Questions About flights to Depew

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Depew with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the BUF airport.

What is the cheapest month to fly to Depew?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Depew are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Depew?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 15 to choose from for your flight to Depew.

What airport is best to fly into Depew?

When you’re planning your trip to Depew, convenience is the name of the game. Luckily, Depew Buffalo Niagara Intl. Airport is nearby so you can deplane and get going on checking off everything on your Depew must-do list.

How much are flights to Depew?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Depew on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $98, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Depew?

The trick to saving a stack of cash on your flight to Depew? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $98 right now, why wait?

Depew Flight Information
Destination airport
Buffalo Niagara Intl.
Destination airport IATA code
BUF
Roundtrip price
$98

Last Minute Hotel Deals in Depew

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in ...
7.4/10 Good! (2,771 reviews)
"Atleast a water bottle have been provided in room. Rest is awesome"

Reviewed on Jun 12, 2026

Get rates
M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the helpful ...
8/10 Very Good! (3,083 reviews)
"Spacious and clean rooms- several people could do yoga in the room! Perfect to stretch before or after a very long flight. Comfortable beds, friendly staff."

Reviewed on Jun 13, 2026

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Buffalo Airport Hotel
Garden Place Hotel

Garden Place Hotel

3.5 out of 5
6615 Transit Road Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free parking, and a free airport shuttle. Our guests praise the helpful staff and ...
7.6/10 Good! (2,412 reviews)
"It appears the facility may be restoring the building. But there were gross stains on the “couch” in our room. The walls were all banged up and looked gross and I was afraid of what might get on me in the bed. We were in the 3rd floor and maybe they haven’t worked on that floor yet. The floorboards ..."

Reviewed on Jun 13, 2026

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Garden Place Hotel
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 out of 5
100 Holtz Dr Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (2,173 reviews)
"good"

Reviewed on Jun 14, 2026

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Sleep Inn & Suites Buffalo Airport
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 out of 5
2761 Long Road Grand Island NY
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,877 reviews)
"The hotel is very nice. We had a very quiet, clean room. The breakfast food was very good and they kept bringing out fresh. The front desk clerk was very nice. The bed was comfortable"

Reviewed on Jun 14, 2026

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Holiday Inn Express Grand Island - Niagara Falls by IHG
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3 out of 5
125 High St Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,848 reviews)
"The hotel was clean, the staff was very polite, courteous and helpful. The only thing I can see needs help is the valet service. We were in the city for a concert along with other guest who were also using the valet service and there was only one person parking and retrieving vehicles. Since there ..."

Reviewed on Jun 14, 2026

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Wyndham Garden Buffalo Downtown
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3 out of 5
145 Innkeepers Lane Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,097 reviews)
"Room was clean and helpful staff. Breakfast was also ok."

Reviewed on Jun 13, 2026

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La Quinta Inn & Suites by Wyndham Buffalo Amherst
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza Buffalo NY
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
8.2/10 Very Good! (1,797 reviews)
"Desk manager was very hands on and helpful locating my towed car. Much appreciated. The breakfast was awful and overpriced."

Reviewed on Jun 13, 2026

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Hyatt Regency Buffalo / Hotel and Conference Center
See all 894 properties in Depew
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.