Search Cheap Flights to
Muscatine

Photo by Bill Eaker

Search 400 airlines and 321,000 hotels worldwide.

Stop Planning & Start Exploring

FREE 24 hour cancellation on most flights

Muscatine Flights as Low as $226

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Delta
Delta
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
American Airlines
Delta
American Airlines
United
American Airlines
American Airlines
American Airlines
United
American Airlines

Cheap Flights to Muscatine

Fall in love at first flight with your vacation to Muscatine by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to Muscatine on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in Muscatine, the good times start rolling. So buckle up, you’re in for a fun ride.

Just the right flight

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to Muscatine with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the MLI airport.

Frequently Asked Questions About flights to Muscatine

What is the cheapest month to fly to Muscatine?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to Muscatine are in July, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to Muscatine?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to Muscatine.

What airport is best to fly into Muscatine?

When you’re planning your trip to Muscatine, convenience is the name of the game. Luckily, Muscatine Quad City Intl. Airport is nearby so you can deplane and get going on checking off everything on your Muscatine must-do list.

How much are flights to Muscatine?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to Muscatine on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $226, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to Muscatine?

The trick to saving a stack of cash on your flight to Muscatine? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $226 right now, why wait?

Can I fly to Muscatine right now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to  right now?” When it’s time to book your flight, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

Muscatine Flight Information
Destination airport
Quad City Intl.
Destination airport IATA code
MLI
Roundtrip price
$225

Last Minute Hotel Deals in Muscatine

The Sage Hotel
The Sage Hotel
2 out of 5
2402 Park Ave, Muscatine, IA
The price is $66 per night from May 9 to May 10
$66
per night
May 9 - May 10
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
6.8/10 (14 reviews)
"I didn’t like that the advertised 6am included breakfast was completely unavailable, including no personnel on station at all at 6am. Absolutely no options, signs, communication etc."

Reviewed on Mar 13, 2024

The Sage Hotel
Best Western Muscatine / Pearl City Hotel
Best Western Muscatine / Pearl City Hotel
2.5 out of 5
305 Cleveland St, Muscatine, IA
The price is $92 per night from May 13 to May 14
$92
per night
May 13 - May 14
Stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (378 reviews)
"Property was very affordable and accommodating"

Reviewed on Apr 29, 2024

Best Western Muscatine / Pearl City Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4 out of 5
119 Mississippi Drive West, Muscatine, IA
The price is $167 per night from May 31 to Jun 1
$167
per night
May 31 - Jun 1
Stay at this 4-star business-friendly hotel in Muscatine. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Riverside Park ...
9.6/10 Exceptional! (217 reviews)
"Nice treat for myself."

Reviewed on May 4, 2024

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
AmericInn by Wyndham Muscatine
AmericInn by Wyndham Muscatine
2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
The price is $81 per night from May 13 to May 14
$81
per night
May 13 - May 14
Book a stay at this business-friendly hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and ...
7.4/10 Good! (310 reviews)
"The staff was very helpful, a good place to stay and a convenient location"

Reviewed on Apr 9, 2024

AmericInn by Wyndham Muscatine
Hampton Inn Muscatine
Hampton Inn Muscatine
2.5 out of 5
3303 N Port Drive, Muscatine, IA
The price is $120 per night from Jun 2 to Jun 3
$120
per night
Jun 2 - Jun 3
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast in our reviews. Popular attractions Muscatine ...
8.4/10 Very Good! (369 reviews)
Amazing Staff and Clean Overall.
"Staff is amazing and room was ok overall. Staff alone wanted me to give it a 5 out of 5, but I have to ding them on the room. It was clean and comfortable overall, but the furniture is dated and the couch in our suite is old and had what appeared to be grease stains from someone’s head. We are not ..."

Reviewed on May 6, 2024

Hampton Inn Muscatine
Comfort Inn Muscatine near Hwy 61
Comfort Inn Muscatine near Hwy 61
2.5 out of 5
115 Cleveland St, Muscatine, IA
The price is $84 per night from May 26 to May 27
$84
per night
May 26 - May 27
Stay at this hotel in Muscatine. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Muscatine Aquatic Center and Geneva Golf and Country ...
7.6/10 Good! (152 reviews)
"Reñiability"

Reviewed on May 5, 2024

Comfort Inn Muscatine near Hwy 61
Wyndham Moline on John Deere Commons
Wyndham Moline on John Deere Commons
3.5 out of 5
1415 River Dr, Moline, IL
The price is $101 per night from May 20 to May 21
$101
per night
May 20 - May 21
Book a stay at this eco-certified hotel in Moline. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (1,004 reviews)
"This hotel was in a nice area within walking distance to many restaurants and sights on the Mississippi River."

Reviewed on May 5, 2024

Wyndham Moline on John Deere Commons
Stoney Creek Hotel Quad Cities - Moline
Stoney Creek Hotel Quad Cities - Moline
2.5 out of 5
101 18th St, Moline, IL
The price is $113 per night from May 12 to May 13
$113
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Moline. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.2/10 Very Good! (1,000 reviews)
"Very clean and comfortable"

Reviewed on May 5, 2024

Stoney Creek Hotel Quad Cities - Moline
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.