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Hotels in Southeastern Indiana

Choose from 1165 Southeastern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
  • 5 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (2,868 reviews)
Super friendly staff, pool was a little cloudy, the rooms were a little dusty, but other than that really good, would book here again

Reviewed on Mar 25, 2026

Radisson Hotel Louisville North
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
  • 5 min drive from KFC Yum Center
Stay at this hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Louisville Slugger Museum and KFC Yum Center are located ...
5/10 (9 reviews)
Have someone on staff at hotel for assistance clean rooms better

Reviewed on Mar 20, 2026

Derby Hotel & Suites
Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

3.5 out of 5
700 West Riverside Drive Jeffersonville IN
  • 18 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,000 reviews)
Hotel staff was great, in my opinion, the hotel is a little dated, given the condition of the bathroom, but the rooms were clean. I would stay again!

Reviewed on Mar 9, 2026

Sheraton Louisville Riverside by Marriott
Motel 6 Jeffersonville, In - Louisville

Motel 6 Jeffersonville, In - Louisville

2 out of 5
2012 Hospitality Way Clarksville IN
  • 7 min drive from KFC Yum Center
Stay at this motel in Clarksville. Enjoy free parking, a 24-hour front desk, and daily housekeeping. Our guests praise the clean rooms in our reviews. Popular ...
6.2/10 (412 reviews)
Stole my cleaning fee, regardless of leaving room in the same state I found it. Entire motel reaked of mold and weed. Beds are absolutely garbage. Staff gave us attitude when we asked for more towels, because the two tiny ones they provided weren't enough for two grown men. Seriously, I've no problem ...

Reviewed on Mar 24, 2026

Motel 6 Jeffersonville, In - Louisville
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Book a stay at this family-friendly resort in French Lick. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions French Lick Scenic Railway and ...
7.6/10 Good! (190 reviews)
The staff was wonderful but the rooms are outdated there was rust everywhere. The water was so cold u could only be in it for an hour. It was definitely much smaller then expected and the rooms dont come with the water park access u have to buy thise separately. The food was all microwave food except ...

Reviewed on Mar 18, 2026

Big Splash Adventure Indoor Water Park & Resort
Candlewood Suites Louisville North by IHG

Candlewood Suites Louisville North by IHG

2.5 out of 5
1419 Bales Lane Clarksville IN
  • 12 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the helpful staff ...
8.4/10 Very Good! (426 reviews)
The room was very clean when we got in and well stocked with the dishes needed for us. The night shift clerk was friendly and we got into our room quickly and smoothly. Highly recommend this hotel!

Reviewed on Mar 24, 2026

Candlewood Suites Louisville North by IHG
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
  • 11 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,010 reviews)
Didn’t stay. just was charged as if I did.

Reviewed on Mar 24, 2026

Comfort Inn & Suites Clarksville - Louisville North
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
  • 16 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.6/10 Exceptional! (456 reviews)
Enjoyed the stay,

Reviewed on Mar 22, 2026

Hilton Garden Inn Jeffersonville Louisville North
Best Western Plus French Lick

Best Western Plus French Lick

2.5 out of 5
613 S Arnold F Habig Boulevard French Lick IN
  • 2 hours drive from KFC Yum Center
Stay at this hotel in French Lick. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9/10 Wonderful! (1,000 reviews)
Bot enough places to eat dinner

Reviewed on Mar 23, 2026

Best Western Plus French Lick
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

2.5 out of 5
360 Triangle Dr Sellersburg IN
  • 23 min drive from KFC Yum Center
Book a stay at this business-friendly hotel in Sellersburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,003 reviews)
Very nice pool

Reviewed on Mar 23, 2026

Ramada by Wyndham Sellersburg/Louisville North
The Villas at French Lick Springs

The Villas at French Lick Springs

3 out of 5
8718 W State Road 56 French Lick IN
  • 2 hours drive from KFC Yum Center
Stay at this condo in French Lick. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (295 reviews)
The beds were uncomfortable...slept in chair,tv in bedroom was smaller than my laptop screen...had to clean spider webs from hot tub before use..turned on jets and 2 multi-leg critters blew out of the jets into the tub with me...ended up leaving early

Reviewed on Mar 24, 2026

The Villas at French Lick Springs
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
  • 23 min walk from KFC Yum Center
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free breakfast, free parking, and a fitness center. Our guests praise the breakfast and ...
9.2/10 Wonderful! (666 reviews)
Everything was wonderful . The location is perfect . Staff was over the top helpful and friendly . The room , lobby , pool , whirlpool , laundry etc all was like family and friends . Best place I have stayed in my travels . I didn’t want to leave . I’m Buddist , but a church choir played a concert ...

Reviewed on Mar 24, 2026

TownePlace Suites by Marriott Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Southeastern Indiana

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $53. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Southeastern Indiana hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Southeastern Indiana. No matter your reason for visiting Southeastern Indiana, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Southeastern Indiana hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Southeastern Indiana?

With over 1,165 hotels in Southeastern Indiana, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $53.

How to find cheap car rentals in Southeastern Indiana?

Finding a cheap car rental deal in Southeastern Indiana is as easy as scoring cheap hotels in Southeastern Indiana. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.