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A coastal archaeological site with ruins and boats on the water.

Santiago
Veraguas
Panama
Mexico and Central America
Hotwire.com

Santiago Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Riande Aeropuerto Hotel & Casino

4 out of 5

Price was $1,247, price is now $849 per person

$849

per person

Jan 5 - Jan 9

found 2 days ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.

Muy buena la atención al cliente y lo recomiendo.

Reviewed on Oct 11, 2026

Megapolis Hotel Panamá

4.5 out of 5

Price was $2,000, price is now $1,000 per person

$1,000

per person

Jan 5 - Jan 9

found 2 days ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

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Reviewed on Oct 10, 2026

Central Hotel Panama Casco Viejo

4 out of 5

Price was $1,853, price is now $1,198 per person

$1,198

per person

Jan 5 - Jan 9

found 2 days ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

I loved my stay here I’d come back here in a heart beat the next time I’m in Panama. The staff, customer service, amenities, suites, pool, and everything above. I felt so safe and cared for here thank you so much.

Reviewed on Oct 11, 2026

Las Clementinas

3.5 out of 5

Price was $1,566, price is now $1,118 per person

$1,118

per person

Dec 4 - Dec 11

found 1 day ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,211, price is now $892 per person

$892

per person

Jan 5 - Jan 9

found 2 days ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Casa Lefevre By Wynwood House

3 out of 5

Price was $1,603, price is now $1,182 per person

$1,182

per person

Nov 29 - Dec 6

found 6 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Villa Caprichosa

2.5 out of 5

Price was $1,173, price is now $866 per person

$866

per person

Nov 13 - Nov 16

found 6 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this beach hotel in Taboga. Enjoy free breakfast, free WiFi, and a free ferry terminal shuttle. Popular attraction Taboga Beach is located nearby.

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5 out of 5

Price was $1,683, price is now $1,256 per person

$1,256

per person

Jan 5 - Jan 9

found 2 days ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.