Search Deals onSantiago Vacation Packages
Santiago Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá
Price was $1,225, price is now $976 per person
$976
per person
Nov 25 - Nov 30
found 19 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Megapolis Hotel Panamá
Price was $2,970, price is now $1,683 per person
$1,683
per person
Dec 29 - Jan 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
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Reviewed on Oct 10, 2026
Central Hotel Panama Casco Viejo
Save 100% on your flight
Price was $3,412, price is now $2,008 per person
$2,008
per person
Dec 29 - Jan 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Clementinas
Price was $1,486, price is now $1,102 per person
$1,102
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this aparthotel in Panama City. Enjoy free WiFi, parking (surcharge), and an airport shuttle (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Mallet by Wynwood House
Price was $1,946, price is now $1,505 per person
$1,505
per person
Nov 24 - Nov 29
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect.
The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us.
I would stay here again in a heart beat.
It’s a must stay!
Reviewed on Sep 16, 2026
Riande Aeropuerto Hotel & Casino
Price was $1,894, price is now $1,480 per person
$1,480
per person
Dec 29 - Jan 2
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Nice place for a 1 night stay. Nothing fancy. Rooms and hotel a little outdated but the breakfast was good. So a nice place for a 1 night stay during a layover.
Reviewed on Oct 10, 2026
Amarla Boutique Hotel Casco Viejo Adults Only
Price was $1,473, price is now $1,185 per person
$1,185
per person
Jan 5 - Jan 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
The hotel lives up to its boutique name and the vibe fits perfectly in the beautiful Casco Viejo neighborhood. My room was lavishly decorated. The included breakfasts are much elevated from a typical breakfast buffet offering. Each day’s meal consists of a fresh fruit bowl, a full entrée from the menu, juice and coffee.
The staff were all welcoming, attentive, and took so much pride in their work.
Reviewed on Oct 11, 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Price was $1,744, price is now $1,410 per person
$1,410
per person
Nov 23 - Nov 28
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. Popular attractions Multiplaza Pacific Mall and Avenida Balboa are located nearby.
Santiago Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santiago Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Wed, Oct 14 - Tue, Oct 27
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$257 Roundtrip, found 1 hour ago
$257
Roundtrip
found 1 hour ago
Sun, Oct 18 - Thu, Oct 22
MEX
Mexico City Intl.
PTY
Tocumen Intl.
$470 Roundtrip, just found
$470
Roundtrip
just found
Sat, Jan 30 - Wed, Feb 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$522 Roundtrip, found 7 hours ago
$522
Roundtrip
found 7 hours ago
Sun, Jan 24 - Fri, Jan 29
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$537 Roundtrip, just found
$537
Roundtrip
just found
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