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UNESCO World Heritage Site Fort San Jeronimo located in Portobelo, Panama.

Santiago
Veraguas
Panama
Mexico and Central America
Hotwire.com

Santiago Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

2 out of 5

Price was $807, price is now $518 per person

$518

per person

Jun 11 - Jun 14

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and a garden. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Price was $1,987, price is now $1,352 per person

$1,352

per person

May 24 - May 30

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Price was $1,474, price is now $1,091 per person

$1,091

per person

Jun 7 - Jun 12

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Villa Caprichosa

3 out of 5

Price was $1,360, price is now $1,027 per person

$1,027

per person

May 27 - Jun 3

found 7 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this beach hotel in Taboga. Enjoy free breakfast, free WiFi, and private pools. Popular attraction Taboga Beach is located nearby.

W Panama

5 out of 5

Price was $1,791, price is now $1,394 per person

$1,394

per person

Jun 18 - Jun 25

found 8 hours ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy 2 restaurants, 3 hot tubs, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions Via Espana and Avenida Balboa are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,271, price is now $994 per person

$994

per person

Jun 7 - Jun 12

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.

Pink Palace Panama

3 out of 5

Price was $1,559, price is now $1,219 per person

$1,219

per person

May 27 - Jun 3

found 7 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Stay at this B&B in Punta Chame. Enjoy free WiFi, free parking, and room service.

The Westin Panama

4 out of 5

Price was $1,634, price is now $1,285 per person

$1,285

per person

Jun 18 - Jun 25

found 8 hours ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy a full-service spa, breakfast (surcharge), and 24-hour room service. Popular attractions Albrook Shopping Mall and Multiplaza Pacific Mall are located nearby.