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Santiago Vacation Packages

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UNESCO World Heritage Site Fort San Jeronimo located in Portobelo, Panama.

Santiago
Veraguas
Panama
Mexico and Central America
Hotwire.com

Santiago Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

2 out of 5

Price was $1,220, price is now $746 per person

$746

per person

Jun 28 - Jul 3

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and a garden. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Hilton Panama

5 out of 5

Save 100% on your flight

Price was $1,891, price is now $1,356 per person

$1,356

per person

Jun 12 - Jun 20

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy a full-service spa, 4 restaurants, and an attached winery. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Price was $1,395, price is now $1,015 per person

$1,015

per person

May 27 - May 30

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Waldorf Astoria Panama

5 out of 5

Save 100% on your flight

Price was $1,748, price is now $1,315 per person

$1,315

per person

Jun 12 - Jun 20

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions Via Espana and Avenida Balboa are located nearby.

Yoo by Wynwood House

4 out of 5

Price was $1,344, price is now $1,014 per person

$1,014

per person

May 27 - Jun 3

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Stay at this condo in Panama City. Enjoy free WiFi, a fitness center, and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Villa Caprichosa

3 out of 5

Price was $1,360, price is now $1,027 per person

$1,027

per person

May 27 - Jun 3

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to Panama City (PTY)

Book a stay at this beach hotel in Taboga. Enjoy free breakfast, free WiFi, and private pools. Popular attraction Taboga Beach is located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Price was $1,235, price is now $936 per person

$936

per person

May 27 - May 30

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Radisson Riviera Panama

4 out of 5

Price was $1,287, price is now $990 per person

$990

per person

Jun 27 - Jul 4

found 1 day ago

Roundtrip flight included

New York (JFK) to Panama City (PTY)

Book a stay at this spa hotel in Punta Chame. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Playa Malibú is located nearby.