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Hotels in Santa Maria

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Historic Santa Maria Inn

Historic Santa Maria Inn

3.5 out of 5
801 S Broadway Santa Maria CA
  • 4 min drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Santa Maria. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful ...
8.4/10 Very Good! (1,891 reviews)
Nice people...friendly...attentive.

Reviewed on Jan 12, 2026

Historic Santa Maria Inn
Hampton Inn & Suites Santa Maria

Hampton Inn & Suites Santa Maria

2.5 out of 5
2190 Preisker Lane Santa Maria CA
  • 6 min drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Santa Maria. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.2/10 Wonderful! (1,003 reviews)
The rooms, beds, and bathrooms were super clean, the breakfast was excellent, and the staff were very attentive. My family and I had a wonderful stay. If I had to travel to Santa Maria again, I would choose the same hotel.

Reviewed on Jan 12, 2026

Hampton Inn & Suites Santa Maria
Motel 6 Santa Maria, CA - North

Motel 6 Santa Maria, CA - North

2 out of 5
2040 North Preisker Lane Santa Maria CA
  • 6 min drive from Marian Regional Medical Center
Stay at this motel in Santa Maria. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.6/10 Good! (1,049 reviews)
The staff is nice and gronds are clean

Reviewed on Jan 14, 2026

Motel 6 Santa Maria, CA - North
Radisson Hotel Santa Maria

Radisson Hotel Santa Maria

3.5 out of 5
3455 Skyway Dr Santa Maria CA
  • 10 min drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Santa Maria. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
7.4/10 Good! (1,323 reviews)
Room was great, front desk receptionist were helpful and friendly

Reviewed on Jan 5, 2026

Radisson Hotel Santa Maria
Homewood Suites by Hilton Santa Maria

Homewood Suites by Hilton Santa Maria

3 out of 5
2100 N Broadway Santa Maria CA
  • 6 min drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Santa Maria. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (52 reviews)
Yes

Reviewed on Jan 13, 2026

Homewood Suites by Hilton Santa Maria
Hotel Avanti

Hotel Avanti

2 out of 5
1107 N Broadway Santa Maria CA
  • 4 min drive from Marian Regional Medical Center
Stay at this hotel in Santa Maria. Enjoy free WiFi, parking (surcharge), and Netflix. Popular attractions Rancho Bowl and Santa Maria Civic Theatre are located ...
9/10 Wonderful! (294 reviews)
Very clean room with renovated features - including recessed lighting and modern bathroom fixtures

Reviewed on Jan 3, 2026

Hotel Avanti
Best Western Plus Big America

Best Western Plus Big America

2.5 out of 5
1725 N Broadway Santa Maria CA
  • 5 min drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Santa Maria. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,003 reviews)
Great room and excellent service and breakfast.

Reviewed on Jan 4, 2026

Best Western Plus Big America
Cottage Inn By The Sea

Cottage Inn By The Sea

3 out of 5
2351 Price St Pismo Beach CA
  • 48 min drive from Marian Regional Medical Center
Book a stay at this beach hotel in Pismo Beach. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,184 reviews)
Cute little stay with my partner. Would happily return again for the ocean view and that exceptionally cozy fireplace!

Reviewed on Jan 14, 2026

Cottage Inn By The Sea
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

3.5 out of 5
2241 Price Street Pismo Beach CA
  • 48 min drive from Marian Regional Medical Center
Book a stay at this beach hotel in Pismo Beach. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,601 reviews)
Great stay. Easy access to the beach. Clean rooms

Reviewed on Jan 12, 2026

SeaCrest OceanFront Hotel
Sideways Inn

Sideways Inn

3 out of 5
114 E Highway 246 Buellton CA
  • 1 hour drive from Marian Regional Medical Center
Book a stay at this business-friendly hotel in Buellton. Enjoy free WiFi, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the ...
8.8/10 Excellent! (1,549 reviews)
Only complaint was that although I asked for cleaning service it was not done.

Reviewed on Jan 15, 2026

Sideways Inn
Wine Valley Inn

Wine Valley Inn

3 out of 5
1564 Copenhagen Dr Solvang CA
  • 1 hour drive from Marian Regional Medical Center
Book a stay at this spa hotel in Solvang. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
9/10 Wonderful! (2,315 reviews)
Clean room, central location to all the town has to offer... and when we left sunglasses in our room upon checking out, the staff notified us right away with a friendly phone call!

Reviewed on Jan 16, 2026

Wine Valley Inn
Chumash Casino Resort

Chumash Casino Resort

4 out of 5
3400 East Highway 246 Santa Ynez CA
  • 1 hour drive from Marian Regional Medical Center
Book a stay at this spa resort in Santa Ynez. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
9.2/10 Wonderful! (1,968 reviews)
Overall this place is a 5star everything is awesome and clean

Reviewed on Jan 15, 2026

Chumash Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find cheap hotels in Santa Maria

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For you, intrepid voyager, Hotwire has a large selection of the best hotels in Santa Maria.

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If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $56. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get great Santa Maria hotel deals at the last minute.

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Frequently Asked Questions About Santa Maria hotels

Where can I find the best last-minute travel deals?

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How many hotels are there in Santa Maria?

With over 1,351 hotels in Santa Maria, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $56.

How to find cheap car rentals in Santa Maria?

Finding a cheap car rental deal in Santa Maria is as easy as scoring cheap hotels in Santa Maria. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can unlock great car rental deals if you book a Hotwire Hot Rate at the last minute.