Search Deals onSanta Isabel Vacation Packages
Santa Isabel Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Las Americas Golden Tower Panama
Price was $1,153, price is now $878 per person
$878
per person
Nov 23 - Nov 27
found 18 hours ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
The breakfast was great and the rooms were comfortable
Reviewed on Sep 3, 2026
Megapolis Hotel Panamá
Save 100% on your flight
Price was $1,907, price is now $1,004 per person
$1,004
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
I thoroughly enjoyed my stay with a fantastic view from both bedrooms. The staff were extremely pleasant and helpful. My Spanish is very limited and almost everyone was able to communicate with me using English. I looked forward to breakfast every morning as they had a wide variety of dishes to choose from.
I most definitely will be back!
Reviewed on Sep 5, 2026
Central Hotel Panama Casco Viejo
Save 100% on your flight
Price was $1,612, price is now $960 per person
$960
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco.
The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.
Reviewed on Sep 2, 2026
Casa Mallet by Wynwood House
Price was $1,375, price is now $913 per person
$913
per person
Oct 19 - Oct 23
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Nice apartment ! Clean and great location
Reviewed on Aug 13, 2026
Decapolis Hotel Panama City
Price was $1,231, price is now $891 per person
$891
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free breakfast, free WiFi, and free valet parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Riande Aeropuerto Hotel & Casino
Price was $1,248, price is now $911 per person
$911
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Hyatt Regency Panama City
Price was $1,388, price is now $1,038 per person
$1,038
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Hotel Riu Plaza Panama
Price was $1,256, price is now $962 per person
$962
per person
Oct 11 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
El staff son muy atentos
Reviewed on Sep 5, 2026
Santa Isabel Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santa Isabel Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 2 hours ago
$264
Roundtrip
found 2 hours ago
Mon, Sep 7 - Mon, Sep 28
MIA
Miami Intl.
PTY
Tocumen Intl.
$392 Roundtrip, found 4 hours ago
$392
Roundtrip
found 4 hours ago
Mon, Mar 1 - Wed, Mar 17
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$517 Roundtrip, found 1 hour ago
$517
Roundtrip
found 1 hour ago
Fri, Oct 16 - Thu, Oct 22
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$540 Roundtrip, found 12 hours ago
$540
Roundtrip
found 12 hours ago
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