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Santa Isabel Vacation Packages

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Santa Isabel
Colón
Panama
Mexico and Central America
Hotwire.com

Santa Isabel Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Villa Botero By Casa Mojito B&B

3 out of 5

Save 100% on your flight

Price was $1,165, price is now $666 per person

$666

per person

May 4 - May 11

found 2 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Save 100% on your flight

Price was $1,890, price is now $1,177 per person

$1,177

per person

May 3 - May 10

found 12 hours ago

Roundtrip non-stop flight included

Columbus (CMH) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Hotel Riu Plaza Panama

5 out of 5

Price was $1,312, price is now $846 per person

$846

per person

May 3 - May 10

found 12 hours ago

Roundtrip non-stop flight included

Columbus (CMH) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Casa Mallet by Wynwood House

4 out of 5

Save 100% on your flight

Price was $3,077, price is now $2,014 per person

$2,014

per person

Apr 2 - Apr 7

found 1 day ago

Roundtrip non-stop flight included

Miami (MIA) to Panama City (PTY)

Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,042, price is now $691 per person

$691

per person

Apr 23 - Apr 26

found 2 days ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Hyatt Regency Panama City

4.5 out of 5

Price was $1,387, price is now $984 per person

$984

per person

May 3 - May 10

found 12 hours ago

Roundtrip non-stop flight included

Columbus (CMH) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Playa Caracol

3.5 out of 5

Save 100% on your flight

Price was $1,300, price is now $946 per person

$946

per person

May 14 - May 20

found 9 hours ago

Roundtrip flight included

Miami (MIA) to Panama City (PTY)

Book a stay at this beach villa in Punta Chame. Enjoy free WiFi, free parking, and 3 outdoor pools. Popular attraction Playa Malibú is located nearby.

Dreams Playa Bonita Panama - All Inclusive

4 out of 5

Save 100% on your flight

Price was $2,157, price is now $1,580 per person

$1,580

per person

May 3 - May 10

found 12 hours ago

Roundtrip non-stop flight included

Columbus (CMH) to Panama City (PTY)

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.