Search Deals on
Santa Isabel Vacation Packages

Build your package with 2 more options

Leaving from

Going to

Departing

Returning

Travelers

Room 1

Adults

ChildrenAges 2 to 17

InfantsYounger than 2

Add specific hotel dates

Santa Isabel
Colón
Panama
Mexico and Central America
Hotwire.com

Santa Isabel Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.

Hotel Riu Plaza Panama

5 out of 5

Price was $890, price is now $647 per person

$647

per person

Mar 4 - Mar 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Mahogany Suites

2 out of 5

Price was $1,490, price is now $700 per person

$700

per person

Mar 29 - Apr 4

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this golf hotel in Arraijan. Enjoy free WiFi, a golf course, and an outdoor pool. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Central Hotel Panama Casco Viejo

4 out of 5

Save 100% on your flight

Price was $1,876, price is now $1,144 per person

$1,144

per person

Mar 19 - Mar 23

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

La Concordia Boutique Hotel

4 out of 5

Save 100% on your flight

Price was $2,002, price is now $1,430 per person

$1,430

per person

Mar 19 - Mar 23

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this family-friendly hotel in Panama City. Enjoy free WiFi, a rooftop terrace, and onsite spa services. Our guests praise the helpful staff and the property condition in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Megapolis Hotel Panamá

4.5 out of 5

Price was $1,256, price is now $906 per person

$906

per person

Mar 4 - Mar 8

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.

Playa Caracol Residences Vacation Rental

3.5 out of 5

Price was $1,021, price is now $752 per person

$752

per person

Mar 19 - Mar 23

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Stay at this apartment in Punta Chame. Enjoy free WiFi, free parking, and 2 outdoor pools. Popular attraction Playa Malibú is located nearby.

Dreams Playa Bonita Panama - All Inclusive

4 out of 5

Price was $1,679, price is now $1,264 per person

$1,264

per person

Mar 19 - Mar 23

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to Panama City (PTY)

Book a stay at this beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.

Villa Botero By Casa Mojito B&B

3 out of 5

Price was $1,092, price is now $824 per person

$824

per person

Feb 26 - Mar 2

found 18 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

Book a stay at this golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.