Search Deals onSanta Isabel Vacation Packages
Santa Isabel Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel
Price was $1,019, price is now $793 per person
$793
per person
Jan 14 - Jan 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Amador Causeway are located nearby.
Good
Reviewed on Oct 10, 2026
Megapolis Hotel Panamá
Save 100% on your flight
Price was $1,942, price is now $1,093 per person
$1,093
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Very nice, clean, would recommend to anyone
Reviewed on Oct 25, 2026
Central Hotel Panama Casco Viejo
Price was $1,871, price is now $1,159 per person
$1,159
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Casa Mallet by Wynwood House
Save 100% on your flight
Price was $2,462, price is now $1,760 per person
$1,760
per person
Jan 14 - Jan 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, parking (surcharge), and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect.
The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us.
I would stay here again in a heart beat.
It’s a must stay!
Reviewed on Sep 16, 2026
Riande Aeropuerto Hotel & Casino
Price was $1,197, price is now $924 per person
$924
per person
Dec 4 - Dec 7
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
Villa Marina Hotel
Price was $1,765, price is now $1,390 per person
$1,390
per person
Nov 25 - Dec 3
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this family-friendly hotel in Las Escobas del Venado. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attraction Venao Beach is located nearby.
SAND DIAMOND HOTEL
Price was $1,401, price is now $1,108 per person
$1,108
per person
Nov 25 - Dec 3
found 9 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
Book a stay at this business-friendly hotel in Colon. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Colon 2000 and Colon Free Zone are located nearby.
Wanders Panama by Boutique Apartments
Price was $1,699, price is now $1,345 per person
$1,345
per person
Dec 31 - Jan 4
found 9 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
Book a stay at this spa apartment in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Todo excelente muy lindo
Reviewed on Sep 29, 2026
Santa Isabel Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santa Isabel Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Fri, Nov 6 - Wed, Nov 11
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, just found
$264
Roundtrip
just found
Sat, Jan 30 - Wed, Feb 3
MIA
Miami Intl.
PTY
Tocumen Intl.
$540 Roundtrip, found 2 hours ago
$540
Roundtrip
found 2 hours ago
Sat, Jan 30 - Wed, Feb 3
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$582 Roundtrip, found 3 hours ago
$582
Roundtrip
found 3 hours ago
Mon, Mar 8 - Mon, Mar 15
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$610 Roundtrip, just found
$610
Roundtrip
just found
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