Search Deals onSanta Isabel Vacation Packages
Santa Isabel Flight + Hotel Packages
Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Price was $1,285, price is now $864 per person
$864
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this family-friendly resort in Tocumen. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions Metromall Panama and Los Pueblos Commercial Center are located nearby.
si tienes que hacer escala en panama. este lugar es perfecto. super cerca. te da transporte de aeropuerto hotel y viceversa. Y me toco comer ahi y todo rico. Dormi bien y volveria para ir de compras a panama
Reviewed on Jul 19, 2026
Central Hotel Panama Casco Viejo
Save 100% on your flight
Price was $1,851, price is now $937 per person
$937
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
I really enjoyed my stay at Casco Viejo. I recommend purchasing the breakfast plan. The food was great. I enjoyed the area for walking. Not too far from Panama City.
Reviewed on Jul 13, 2026
Megapolis Hotel Panamá
Price was $1,500, price is now $925 per person
$925
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Nice hotel clean and large room very good breakfast I loved the pool and the polite staff
Reviewed on Jul 19, 2026
Hotel Riu Plaza Panama
Price was $1,248, price is now $878 per person
$878
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
I don’t know where to start! This hotel was amazing! Nice clean rooms, pool nice and clean, breakfast amazing, and drinks were strong. The area is in prime area and I can’t wait to come
Back!
Reviewed on Jul 19, 2026
80m² Luxury Ocean View Apartment PH The Sands, Next to Hilton
Price was $1,743, price is now $1,299 per person
$1,299
per person
Aug 19 - Aug 25
found 23 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy a fitness center, parking (surcharge), and an outdoor pool. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hyatt Regency Panama City
Price was $1,271, price is now $953 per person
$953
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this luxury hotel in Panama City. Enjoy free WiFi, free valet parking, and 2 restaurants. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Absolutely amazing!!! Loved every aspect of it. 10/10 stay and WILL be coming back. The staff were helpful and efficient. The food at breakfast was incredibly fresh and so delicious. The room was perfect and clean.
Reviewed on Jul 18, 2026
Casa Lefevre By Wynwood House
Price was $1,343, price is now $1,020 per person
$1,020
per person
Aug 19 - Aug 25
found 23 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi, cable TV channels, and premium bedding. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Las Americas Golden Tower Panama
Price was $1,182, price is now $899 per person
$899
per person
Oct 8 - Oct 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Book a stay at this spa hotel in Panama City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Albrook Shopping Mall and Avenida Balboa are located nearby.
Clean room
Reviewed on Jul 14, 2026
Santa Isabel Vacation Packages 3-4 Night Stays
Price found within the past 48 hours. Click for updated prices.
Santa Isabel Vacation Packages 5-7 Night Stays
Price found within the past 48 hours. Click for updated prices.
Top Flight Deals
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Tue, Oct 20 - Sun, Oct 25
SJO
Juan Santamaría Intl.
PTY
Tocumen Intl.
$264 Roundtrip, found 4 hours ago
$264
Roundtrip
found 4 hours ago
Wed, Nov 4 - Wed, Nov 11
MIA
Miami Intl.
PTY
Tocumen Intl.
$412 Roundtrip, found 12 hours ago
$412
Roundtrip
found 12 hours ago
Sun, Sep 6 - Thu, Sep 10
FLL
Fort Lauderdale - Hollywood Intl.
PTY
Tocumen Intl.
$477 Roundtrip, found 17 hours ago
$477
Roundtrip
found 17 hours ago
Tue, Nov 17 - Tue, Nov 24
ATL
Hartsfield-Jackson Atlanta Intl.
PTY
Tocumen Intl.
$616 Roundtrip, found 4 days ago
$616
Roundtrip
found 4 days ago
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