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Santa Cruz Vacation Packages

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Santa Cruz Flight + Hotel Packages

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Sep 11 - Sep 15
found 4 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Stay at this 3-star golf B&B in Rio Hato. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Playa Blanca and Farallón Beach are located nearby.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
per person
Jul 18 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 4-star spa hotel in Panama City. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. Popular attractions Albrook Shopping Mall and Via Espana are located nearby.
Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
per person
Aug 11 - Aug 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Panama City (PTY)
Stay at this 3.5-star beach lodge in Bocas del Toro. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions La Gruta Cave and Institute for Tropical Ecology & Conservation - Bocas del Toro Biological Station are located nearby.
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
per person
Aug 24 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)
Stay at this 4-star spa hotel in Isla Frangipani. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews.
Hotel Plaza Herrera

Hotel Plaza Herrera

3 out of 5
per person
Sep 1 - Sep 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this 3-star hotel in Panama City. Enjoy free breakfast, free WiFi, and valet parking (surcharge). Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.
Coral Bay Bungalows

Coral Bay Bungalows

3 out of 5
per person
Aug 11 - Aug 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Panama City (PTY)
Stay at this 3-star resort in Bastimentos. Enjoy free breakfast, free WiFi, and free airport pick-up. Popular attractions Hospital Point and Bastimento-Bocas del Toro Ferry Terminal are located nearby.
The Sands by Wynwood House

The Sands by Wynwood House

2 out of 5
per person
Jul 24 - Jul 27
found 2 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
Stay at this apartment in Panama City. Enjoy free WiFi and an outdoor pool. Popular attractions Albrook Shopping Mall and Cinta Costera are located nearby.

Santa Cruz Vacation Packages 3-4 Night Stays

Price found within the past 48 hours. Click for updated prices.
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Sep 11 - Sep 15
found 4 hours ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Residencia Natural

Residencia Natural

3 out of 5
Save 100% on your flight
per person
Jul 23 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
per person
Jul 18 - Jul 21
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
NAYARA Bocas del Toro

NAYARA Bocas del Toro

4 out of 5
Save 100% on your flight
per person
Aug 24 - Aug 27
found 19 hours ago
Roundtrip non-stop flight included
Charlotte (CLT) to Panama City (PTY)

Santa Cruz Vacation Packages 5-7 Night Stays

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Aug 29 - Sep 3
found 19 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Panama City (PTY)
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5 out of 5
Bella Vista
Save 100% on your flight
per person
Jul 18 - Jul 25
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)

Top Flight Deals

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Copa
Mon, Oct 6 - Tue, Oct 7
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$286 Roundtrip, found 11 hours ago
$286
Roundtrip
found 11 hours ago
Select Copa flight, departing Mon, Oct 6 from Miami Intl. to Enrique Malek Intl., returning Tue, Oct 7, priced at $286 found 11 hours ago
Copa
Fri, Oct 17 - Sun, Oct 26
JFK
John F. Kennedy Intl.
DAV
Enrique Malek Intl.
$819 Roundtrip, found 1 day ago
$819
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Oct 17 from John F. Kennedy Intl. to Enrique Malek Intl., returning Sun, Oct 26, priced at $819 found 1 day ago
United
Sun, Oct 5 - Thu, Oct 9
MIA
Miami Intl.
DAV
Enrique Malek Intl.
$1,008 Roundtrip, found 11 hours ago
$1,008
Roundtrip
found 11 hours ago
Select United flight, departing Sun, Oct 5 from Miami Intl. to Enrique Malek Intl., returning Thu, Oct 9, priced at $1,008 found 11 hours ago
United
Fri, Oct 17 - Sun, Oct 26
EWR
Newark Liberty Intl. Airport
DAV
Enrique Malek Intl.
$1,014 Roundtrip, found 1 day ago
$1,014
Roundtrip
found 1 day ago
Select United flight, departing Fri, Oct 17 from Newark Liberty Intl. Airport to Enrique Malek Intl., returning Sun, Oct 26, priced at $1,014 found 1 day ago