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San Marco Vacations

Pack those stellar shades. We have San Marco vacation deals for you!

If there’s one thing you should spend in this busy world, it’s your vacation days. We know it’s easy to hang onto them, but Hotwire votes for putting them to use. It’s time to let an adventure lead you away from the daily grind. Stock up on what really matters on your trip to San Marco – great memories and a tall tale or two.

Hotwire can help you find your travel bliss with San Marco vacation packages. Bundling your hotel, car and flight means more unexpected fun with the money you saved. We’ll cover the bases; now it’s time for you to get up and go!

Pack everything you want – then take half of it out

We mean it. It’s far too easy to over-pack. We recommend picking your essentials and washing them along the way. Then you’ll have room for that goofy souvenir you know you want – or for some new outfits from that cute boutique you discover.

Bring comfortable walking shoes on your trip to San Marco

No one should have to endure walking tours in dress shoes or high heels. No one.

Bring photocopies of your passport or license

You flew home from a great San Marco vacation but your most important documents stayed behind. We’ve heard that story before and recommend keeping an extra copy on hand – just in case. Hey, at least it wasn’t a family member.

Don’t underestimate the power of earplugs

Among crying babies, rowdy crowds and honking horns, take our word for it. One pair can save you from the zombie-like state of a sleepless night.

Always carry some cash

You’ll be ready for anything from an evil ATM to lost credit cards. Holding a little extra cash in your wallet and carry-on means you can breathe easy if anything unexpected pops up.

Explore like a local

Guidebooks and maps are great for getting an overview of the place, but to really dig in, go where the locals go. Pick up a newspaper or city magazine to see what restaurants and neighborhoods are hot. Check events listings and go see a band or attend a street festival. Or ask your friends for recommendations. You’d be surprised who in your circle knows San Marco well.

San Marco Flight + Hotel packages

Top Hotel Deals

See all 202 Properties in San Marco
Hilton Garden Inn Jacksonville Downtown Southbank

Hilton Garden Inn Jacksonville Downtown Southbank

1201 Kings Avenue, Jacksonville
    3.0 out of 5.0
     
     

    Located in San Marco, this hotel is within 1 mi (2 km) of Jacksonville Historical Center, Museum of Science and History, and Jacksonville Landing. Jacksonville ...

    Hilton Garden Inn Jacksonville Downtown Southbank$81

    Hilton Garden Inn Jacksonville Downtown Southbank$81
    Magnuson Hotel Jacksonville Downtown

    Magnuson Hotel Jacksonville Downtown

    2228 Phillips Highway, Jacksonville
      2.0 out of 5.0
       
       

      Located in San Marco, this motel is within 2 mi (3 km) of Theatre Jacksonville, Museum of Science and History, and Jacksonville Landing. Jacksonville Museum ...

      Magnuson Hotel Jacksonville Downtown$54

      Magnuson Hotel Jacksonville Downtown$54
      Homewood Suites by Hilton Jacksonville Downtown-Southbank

      Homewood Suites by Hilton Jacksonville Downtown-Southbank

      1201 Kings Avenue, Jacksonville
        3.0 out of 5.0
         
         

        Located in San Marco, this hotel is within 1 mi (2 km) of Jacksonville Historical Center, Museum of Science and History, and Jacksonville Landing. Jacksonville ...

        Homewood Suites by Hilton Jacksonville Downtown-Southbank$121

        Homewood Suites by Hilton Jacksonville Downtown-Southbank$121
        Scottish Inn Jacksonville Downtown

        Scottish Inn Jacksonville Downtown

        2300 Phillips Hwy, Jacksonville
          1.5 out of 5.0
           
           

          Located in San Marco, this motel is 0.8 mi (1.3 km) from Theatre Jacksonville and within 3 mi (5 km) of Jacksonville Museum of Modern Art and Museum of Science ...

          Scottish Inn Jacksonville Downtown$50

          Scottish Inn Jacksonville Downtown$50
          Omni Jacksonville Hotel

          Omni Jacksonville Hotel

          245 Water St, Jacksonville
            4.0 out of 5.0
             
             

            The Omni Jacksonville Hotel is downtown, in the cultural and business districts. The hotel is opposite the Times-Union Center for the Performing Arts, one block ...

            Omni Jacksonville Hotel$79

            Omni Jacksonville Hotel$79
            Motel 6 Jacksonville FL Airport Area - South

            Motel 6 Jacksonville FL Airport Area - South

            812 Dunn Ave, Jacksonville
              2.5 out of 5.0
               
               

              Situated near the airport, this hotel is 0.6 mi (1 km) from Anheuser-Busch Brewery and within 6 mi (10 km) of Jacksonville Zoo and Gardens and Oceanway Community ...

              Motel 6 Jacksonville FL Airport Area - South$31

              Motel 6 Jacksonville FL Airport Area - South$31
              Hyatt Regency Jacksonville

              Hyatt Regency Jacksonville

              225 E Coastline Dr, Jacksonville
                4.0 out of 5.0
                 
                 

                This downtown riverfront hotel is in the city's business and retail district next to Jacksonville shopping, dining, and entertainment venues.

                Hyatt Regency Jacksonville$109

                Hyatt Regency Jacksonville$109
                Best Western Southside Hotel & Suites

                Best Western Southside Hotel & Suites

                4580 Collins Rd, Orange Park
                  2.5 out of 5.0
                   
                   

                  Situated in the business district, this hotel is 1.2 mi (1.9 km) from bestbet Orange Park and 2.4 mi (3.8 km) from Jacksonville Naval Air Station. Westside Regional ...

                  Best Western Southside Hotel & Suites$71

                  Best Western Southside Hotel & Suites$71
                  One Ocean Resort & Spa

                  One Ocean Resort & Spa

                  1 Ocean Blvd, Atlantic Beach
                    4.5 out of 5.0
                     
                     

                    One Ocean Resort & Spa is 33 miles from St. Augustine, 16 miles from downtown Jacksonville, and 9 miles from TPC Sawgrass.

                    One Ocean Resort & Spa$210

                    One Ocean Resort & Spa$210
                    Lexington Hotel & Conference Center - Jacksonville Riverwalk

                    Lexington Hotel & Conference Center - Jacksonville Riverwalk

                    1515 Prudential Dr, Jacksonville
                      3.5 out of 5.0
                       
                       

                      The Lexington Hotel & Conference Center – Jacksonville Riverwalk is located across from Jacksonville Landing, on the south bank of the river, 1 mile (1.6 kilometers) ...

                      Top Flight Deals

                      Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.